Publications by authors named "David Selwood"

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Quinoline-Based Neuropilin‑1 Antagonists Exhibit a Pure Antagonist Profile and Block Vascular Endothelial Growth Factor-Induced Pain.
Sara Hestehave, Silvia Dragoni, Philip Fallon, Filipa Mota, Aida Calderon-Rivera, David L Selwood

ACS Pharmacol Transl Sci· November 2025

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The case for targeting latent and lytic Epstein-Barr virus infection in multiple sclerosis.
Gavin Giovannoni, Louisa James, Adekunle A Adeniran, Julian Gold, Lawrence S Young, David L Selwood

Brain· September 2025

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Macrocycle-based PROTACs selectively degrade cyclophilin A and inhibit HIV-1 and HCV.
Lydia S Newton, Clara Gathmann, Sophie Ridewood, Robert J Smith, Andre J Wijaya, David L Selwood

Nat Commun· February 2025

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Delocalized quinolinium-macrocyclic peptides, an atypical chemotype for CNS penetration.
Valeria Pingitore, Jessica Pancholi, Thomas W Hornsby, Justin Warne, Gareth Pryce, David L Selwood

Sci Adv· July 2024

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Neuroprotection in an Experimental Model of Multiple Sclerosis via Opening of Big Conductance, Calcium-Activated Potassium Channels.
Gareth Pryce, Sofia Sisay, Gavin Giovannoni, David L Selwood, David Baker

Pharmaceuticals (Basel)· July 2023

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Therapeutic Validation of GEF-H1 Using a De Novo Designed Inhibitor in Models of Retinal Disease.
Clare Mills, Sandra A Hemkemeyer, Zerin Alimajstorovic, Chantelle Bowers, Malihe Eskandarpour, David L Selwood

Cells· May 2022

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A Series of Substituted Bis-Aminotriazines Are Activators of the Natriuretic Peptide Receptor C.
Robert J Smith, Cristina Perez-Ternero, Daniel Conole, Capucine Martin, Samuel H Myers, David L Selwood

J Med Chem· April 2022

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Reversal of behavioural phenotype by the cannabinoid-like compound VSN16R in fragile X syndrome mice.
Michael J Hurley, Robert M J Deacon, A W Edith Chan, David Baker, David L Selwood

Brain· March 2022

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VEGFA, B, C: Implications of the C-Terminal Sequence Variations for the Interaction with Neuropilins.
Charles Eldrid, Mire Zloh, Constantina Fotinou, Tamas Yelland, Lefan Yu, David L Selwood

Biomolecules· February 2022

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Peptides Derived from Vascular Endothelial Growth Factor B Show Potent Binding to Neuropilin-1.
Filipa Mota, Tamas Yelland, Jennie A Hutton, Jennifer Parker, Anastasia Patsiarika, David L Selwood

Chembiochem· January 2022

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Cannabidiol activates PINK1-Parkin-dependent mitophagy and mitochondrial-derived vesicles.
Adrian Ramirez, William Old, David L Selwood, Xuedong Liu

Eur J Cell Biol· January 2022

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Oligodendrocytes, BK channels and the preservation of myelin.
Maddalena Rupnik, David Baker, David L Selwood

F1000Res· January 2022

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Emerging small-molecule treatments for multiple sclerosis: focus on B cells.
Aaron Gregson, Kaitlyn Thompson, Stella E Tsirka, David L Selwood

F1000Res· June 2020

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Discovery of a novel fluorescent chemical probe suitable for evaluation of neuropilin-1 binding of small molecules.
Daniel Conole, Yi-Tai Chou, Anastasia Patsiarika, Valery Nwabo, Eleni Dimitriou, David L Selwood

Drug Dev Res· June 2020

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Hepatitis C virus exploits cyclophilin A to evade PKR.
Che C Colpitts, Sophie Ridewood, Bethany Schneiderman, Justin Warne, Keisuke Tabata, David L Selwood

Elife· June 2020

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The β4-Subunit of the Large-Conductance Potassium Ion Channel KCa1.1 Regulates Outflow Facility in Mice.
Jacques A Bertrand, Martin Schicht, W Daniel Stamer, David Baker, Joseph M Sherwood, David L Selwood

Invest Ophthalmol Vis Sci· March 2020

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A new patient-derived iPSC model for dystroglycanopathies validates a compound that increases glycosylation of α-dystroglycan.
Jihee Kim, Beatrice Lana, Silvia Torelli, David Ryan, Francesco Catapano, David L Selwood

EMBO Rep· November 2019

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Critical Care Network in the State of Qatar.
Majed Hijjeh, Loua Al Shaikh, Guillaume Alinier, David Selwood, Faisal Malmstrom

Qatar Med J· November 2019

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N -carbonyl-substituted phenothiazines inhibiting lipid peroxidation and associated nitric oxide consumption powerfully protect brain tissue against oxidative stress.
Robert G Keynes, Anastasia Karchevskaya, Dieter Riddall, Charmaine H Griffiths, Tomas C Bellamy, David L Selwood

Chem Biol Drug Des· September 2019

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The Cannabinoid-Like Compound, VSN16R, Acts on Large Conductance, Ca-Activated K Channels to Modulate Hippocampal CA1 Pyramidal Neuron Firing.
Setareh Tabatabaee, David Baker, David L Selwood, Benjamin J Whalley, Gary J Stephens

Pharmaceuticals (Basel)· July 2019

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Biophysical screening methods for extracellular domain peptide receptors, application to natriuretic peptide receptor C ligands.
Daniel Conole, Samuel H Myers, Filipa Mota, Adrian J Hobbs, David L Selwood

Chem Biol Drug Des· June 2019

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Commentary: Reproducible science, why protocols matter.
David L Selwood

Chem Biol Drug Des· June 2019

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Mitochondrial Permeability Transition: A Molecular Lesion with Multiple Drug Targets.
Thomas Briston, David L Selwood, Gyorgy Szabadkai, Michael R Duchen

Trends Pharmacol Sci· January 2019

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Identification of Kinases and Phosphatases That Regulate ATG4B Activity by siRNA and Small Molecule Screening in Cells.
Niccolo Pengo, Krisna Prak, Joana R Costa, Christin Luft, Alexander Agrotis, David L Selwood

Front Cell Dev Biol· November 2018

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Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations.
Eyram Adjogatse, Peter Erskine, Stephen A Wells, John M Kelly, Jonathan D Wilden, David Selwood

Acta Crystallogr D Struct Biol· September 2018

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