Publications by authors named "David Sharples"

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Short-chain diamines are the physiological substrates of PACE family efflux pumps.
Karl A Hassan, Varsha Naidu, Jacob R Edgerton, Karla A Mettrick, Qi Liu, David Sharples

Proc Natl Acad Sci U S A· September 2019

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Pacing across the membrane: the novel PACE family of efflux pumps is widespread in Gram-negative pathogens.
Karl A Hassan, Qi Liu, Liam D H Elbourne, Irshad Ahmad, David Sharples

Res Microbiol· November 2018

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Screening of candidate substrates and coupling ions of transporters by thermostability shift assays.
Homa Majd, Martin S King, Shane M Palmer, Anthony C Smith, Liam Dh Elbourne, David Sharples

Elife· October 2018

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Microbial expression systems for membrane proteins.
Marvin V Dilworth, Mathilde S Piel, Kim E Bettaney, Pikyee Ma, Ji Luo, David Sharples

Methods· September 2018

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Topological Dissection of the Membrane Transport Protein Mhp1 Derived from Cysteine Accessibility and Mass Spectrometry.
Antonio N Calabrese, Scott M Jackson, Lynsey N Jones, Oliver Beckstein, Florian Heinkel, David Sharples

Anal Chem· September 2017

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Characterisation of the DAACS Family Escherichia coli Glutamate/Aspartate-Proton Symporter GltP Using Computational, Chemical, Biochemical and Biophysical Methods.
Moazur Rahman, Fouzia Ismat, Li Jiao, Jocelyn M Baldwin, David J Sharples

J Membr Biol· April 2017

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A Novel and Fast Purification Method for Nucleoside Transporters.
Zhenyu Hao, Maren Thomsen, Vincent L G Postis, Amelia Lesiuk, David Sharples

Front Mol Biosci· July 2016

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Allantoin transport protein, PucI, from Bacillus subtilis: evolutionary relationships, amplified expression, activity and specificity.
Pikyee Ma, Simon G Patching, Ekaterina Ivanova, Jocelyn M Baldwin, David Sharples

Microbiology (Reading)· May 2016

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An ace up their sleeve: a transcriptomic approach exposes the AceI efflux protein of Acinetobacter baumannii and reveals the drug efflux potential hidden in many microbial pathogens.
Karl A Hassan, Liam D H Elbourne, Liping Li, Hasinika K A H Gamage, Qi Liu, David Sharples

Front Microbiol· May 2015

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Molecular mechanism of ligand recognition by membrane transport protein, Mhp1.
Katie J Simmons, Scott M Jackson, Florian Brueckner, Simon G Patching, Oliver Beckstein, David J Sharples

EMBO J· August 2014

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Probing the contacts of a low-affinity substrate with a membrane-embedded transport protein using 1H-13C cross-polarisation magic-angle spinning solid-state NMR.
Simon G Patching, Peter J F Henderson, David J Sharples, David A Middleton

Mol Membr Biol· March 2013

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Molecular basis of alternating access membrane transport by the sodium-hydantoin transporter Mhp1.
Tatsuro Shimamura, Simone Weyand, Oliver Beckstein, Nicholas G Rutherford, Jonathan M Hadden, David Sharples

Science· April 2010

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