Publications by authors named "David Sprinzak"

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Neuralized-like proteins differentially activate Notch ligands.
Alina Airich, Oren Gozlan, Ekaterina Seib, Gittel Leah Shaingarten, Lena-Sophie Wilschrey, David Sprinzak

EMBO Rep· December 2025

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HLA export by melanoma cells decoys cytotoxic T cells to promote immune evasion.
Yoav Chemla, Orit Itzhaki, Stav Melamed, Chen Weller, Yuval Sade, David Sprinzak

Cell· December 2025

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A model of transcriptional bursting dynamics based on coupling between chromatin and enhancer states.
Ofri Axelrod, Udi Binshtok, Brian Gebelein, Hernan Garcia, David Sprinzak

bioRxiv· December 2025

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From genes to patterns: five key dynamical systems concepts to decode developmental regulatory mechanisms.
Usha Kadiyala, David Sprinzak, Nicholas A M Monk, Shannon E Taylor, Berta Verd

Development· July 2025

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Fat4 intracellular domain controls internalization of Fat4/Dchs1 planar polarity membrane complexes.
Yathreb Easa, Olga Loza, Roie Cohen, David Sprinzak

Biophys J· March 2025

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Interplay between Notch signaling and mechanical forces during developmental patterning processes.
Shahar Kasirer, David Sprinzak

Curr Opin Cell Biol· December 2024

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Structural requirements for activity of Mind bomb1 in Notch signaling.
Ruili Cao, Oren Gozlan, Alina Airich, Lena Tveriakhina, Haixia Zhou, David Sprinzak

Structure· October 2024

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Structural Requirements for Activity of Mind bomb1 in Notch Signaling.
Ruili Cao, Oren Gozlan, Lena Tveriakhina, Haixia Zhou, Hanjie Jiang, David Sprinzak

bioRxiv· March 2024

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Local cellular interactions: From signaling to mechanics across development, evolution, and disease.
Anna Bigas, David Sprinzak

Curr Opin Cell Biol· February 2024

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Endothelial Notch1 signaling in white adipose tissue promotes cancer cachexia.
Jacqueline Taylor, Leonie Uhl, Iris Moll, Sana Safatul Hasan, Lena Wiedmann, David Sprinzak

Nat Cancer· November 2023

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Novel Association of the NOTCH Pathway Regulator MIB1 Gene With the Development of Bicuspid Aortic Valve.
Idit Tessler, Juliette Albuisson, Rebeca Piñeiro-Sabarís, Aline Verstraeten, Hatem Elif Kamber Kaya, David Sprinzak

JAMA Cardiol· August 2023

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Cis-inhibition suppresses basal Notch signaling during sensory organ precursor selection.
Tobias Troost, Udi Binshtok, David Sprinzak, Thomas Klein

Proc Natl Acad Sci U S A· June 2023

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Therapeutic gene silencing of leads to lethality in genetically unstable cancer cells.
Sushmita Chatterjee, Gonna Somu Naidu, Inbal Hazan-Halevy, Hanna Grobe, Assaf Ezra, David Sprinzak

Sci Adv· April 2023

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Notch signaling in development and homeostasis.
Oren Gozlan, David Sprinzak

Development· February 2023

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Structure of the planar cell polarity cadherins Fat4 and Dachsous1.
Elliot Medina, Yathreb Easa, Daniel K Lester, Eric K Lau, David Sprinzak

Nat Commun· February 2023

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Precise alternating cellular pattern in the inner ear by coordinated hopping intercalations and delaminations.
Roie Cohen, Shahar Taiber, Olga Loza, Shahar Kasirer, Shiran Woland, David Sprinzak

Sci Adv· February 2023

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Matrix stiffness regulates Notch signaling activity in endothelial cells.
Maibritt Kretschmer, Rose Mamistvalov, David Sprinzak, Angelika M Vollmar, Stefan Zahler

J Cell Sci· January 2023

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Functional Comparison between Endogenous and Synthetic Notch Systems.
Bassma Khamaisi, Vincent C Luca, Stephen C Blacklow, David Sprinzak

ACS Synth Biol· October 2022

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A Nesprin-4/kinesin-1 cargo model for nuclear positioning in cochlear outer hair cells.
Shahar Taiber, Oren Gozlan, Roie Cohen, Leonardo R Andrade, Ellen F Gregory, David Sprinzak

Front Cell Dev Biol· September 2022

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Mechanical forces shaping the development of the inner ear.
Roie Cohen, David Sprinzak

Biophys J· October 2021

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Enhancers with cooperative Notch binding sites are more resistant to regulation by the Hairless co-repressor.
Yi Kuang, Anna Pyo, Natanel Eafergan, Brittany Cain, Lisa M Gutzwiller, David Sprinzak

PLoS Genet· September 2021

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Dynamic spatiotemporal coordination of neural stem cell fate decisions occurs through local feedback in the adult vertebrate brain.
Nicolas Dray, Laure Mancini, Udi Binshtok, Felix Cheysson, Willy Supatto, David Sprinzak

Cell Stem Cell· August 2021

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Biophysics of Notch Signaling.
David Sprinzak, Stephen C Blacklow

Annu Rev Biophys· May 2021

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Roadmap for the multiscale coupling of biochemical and mechanical signals during development.
Pierre-François Lenne, Edwin Munro, Idse Heemskerk, Aryeh Warmflash, Laura Bocanegra-Moreno, David Sprinzak

Phys Biol· April 2021

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Neonatal AAV gene therapy rescues hearing in a mouse model of SYNE4 deafness.
Shahar Taiber, Roie Cohen, Ofer Yizhar-Barnea, David Sprinzak, Jeffrey R Holt

EMBO Mol Med· February 2021

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