Publications by authors named "David Will"

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Building an eDNA surveillance toolkit for invasive rodents on islands: can we detect wild-type and gene drive Mus musculus?
Antoinette J Piaggio, Luke Gierus, Daniel R Taylor, Nick D Holmes, David J Will

BMC Biol· November 2024

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Probing Factor Xa Protein-Ligand Interactions: Accurate Free Energy Calculations and Experimental Validations of Two Series of High-Affinity Ligands.
María Isabel Fernández-Bachiller, Songhwan Hwang, María Elena Schembri, Peter Lindemann, Mónica Guberman, David W Will

J Med Chem· October 2022

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The global contribution of invasive vertebrate eradication as a key island restoration tool.
Dena R Spatz, Nick D Holmes, David J Will, Stella Hein, Zachary T Carter

Sci Rep· August 2022

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Small Molecule Inhibitor Targeting CDT1/Geminin Protein Complex Promotes DNA Damage and Cell Death in Cancer Cells.
Nikolaos Karantzelis, Michalis Petropoulos, Valeria De Marco, David A Egan, Alexander Fish, David W Will

Front Pharmacol· April 2022

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Synthesis and Evaluation of Novel Ring-Strained Noncanonical Amino Acids for Residue-Specific Bioorthogonal Reactions in Living Cells.
Christopher D Reinkemeier, Christine Koehler, Paul F Sauter, Nataliia V Shymanska, Cecile Echalier, David W Will

Chemistry· April 2021

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Globally important islands where eradicating invasive mammals will benefit highly threatened vertebrates.
Nick D Holmes, Dena R Spatz, Steffen Oppel, Bernie Tershy, Donald A Croll, David J Will

PLoS One· January 2020

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A time-resolved live cell imaging assay to identify small molecule inhibitors of FGF2 signaling.
Mennatallah Ahmed, Cyril Legrand, Ana Yagüe Relimpio, Carlo A Beretta, Alina Muschko, David W Will

FEBS Lett· August 2019

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Risk assessment of dietary lead exposure among First Nations people living on-reserve in Ontario, Canada using a total diet study and a probabilistic approach.
Amanda K Juric, Malek Batal, Will David, Donald Sharp, Harold Schwartz

J Hazard Mater· February 2018

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A total diet study and probabilistic assessment risk assessment of dietary mercury exposure among First Nations living on-reserve in Ontario, Canada.
Amanda K Juric, Malek Batal, Will David, Donald Sharp, Harold Schwartz

Environ Res· October 2017

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Small Molecule Inhibitors Targeting Tec Kinase Block Unconventional Secretion of Fibroblast Growth Factor 2.
Giuseppe La Venuta, Sabine Wegehingel, Peter Sehr, Hans-Michael Müller, Eleni Dimou, David W Will

J Biol Chem· August 2016

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Spatially defined InsP3-mediated signaling in embryonic stem cell-derived cardiomyocytes.
Nidhi Kapoor, Joshua T Maxwell, Gregory A Mignery, David Will, Lothar A Blatter

PLoS One· September 2014

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Fragment deconstruction of small, potent factor Xa inhibitors: exploring the superadditivity energetics of fragment linking in protein-ligand complexes.
Marc Nazaré, Hans Matter, David W Will, Michael Wagner, Matthias Urmann

Angew Chem Int Ed Engl· January 2012

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Elevated extracellular K+ inhibits apoptosis of corneal epithelial cells exposed to UV-B radiation.
Katherine R Singleton, David S Will, Mark P Schotanus, Loren D Haarsma, Leah R Koetje

Exp Eye Res· August 2009

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Evidence for C-Cl/C-Br...pi interactions as an important contribution to protein-ligand binding affinity.
Hans Matter, Marc Nazaré, Stefan Güssregen, David W Will, Herman Schreuder

Angew Chem Int Ed Engl· June 2009

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Radial pulse character relationships to systolic blood pressure and trauma outcomes.
John McManus, Andrey L Yershov, David Ludwig, John B Holcomb, Jose Salinas, Will David

Prehosp Emerg Care· January 2006

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Probing the subpockets of factor Xa reveals two binding modes for inhibitors based on a 2-carboxyindole scaffold: a study combining structure-activity relationship and X-ray crystallography.
Marc Nazaré, David W Will, Hans Matter, Herman Schreuder, Kurt Ritter

J Med Chem· July 2005

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Structural requirements for factor Xa inhibition by 3-oxybenzamides with neutral P1 substituents: combining X-ray crystallography, 3D-QSAR, and tailored scoring functions.
Hans Matter, David W Will, Marc Nazaré, Herman Schreuder, Volker Laux

J Med Chem· May 2005

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Custom chemical microarray production and affinity fingerprinting for the S1 pocket of factor VIIa.
Stefan Dickopf, Michael Frank, Hans-Dieter Junker, Sabine Maier, Günther Metz, David W Will

Anal Biochem· December 2004

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Factor Xa inhibitors based on a 2-carboxyindole scaffold: SAR of neutral P1 substituents.
Marc Nazaré, Melanie Essrich, David W Will, Hans Matter, Kurt Ritter

Bioorg Med Chem Lett· August 2004

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Novel factor Xa inhibitors based on a 2-carboxyindole scaffold: SAR of P4 substituents in combination with a neutral P1 ligand.
Marc Nazaré, Melanie Essrich, David W Will, Hans Matter, Kurt Ritter

Bioorg Med Chem Lett· August 2004

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A flexible, palladium-catalyzed indole and azaindole synthesis by direct annulation of chloroanilines and chloroaminopyridines with ketones.
Marc Nazaré, Claudia Schneider, Andreas Lindenschmidt, David William Will

Angew Chem Int Ed Engl· August 2004

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Novel factor Xa inhibitors based on a benzoic acid scaffold and incorporating a neutral P1 ligand.
Marc Nazaré, Hans Matter, Otmar Klingler, Fahad Al-Obeidi, Herman Schreuder, David W Will

Bioorg Med Chem Lett· June 2004

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PNA: Synthetic Polyamide Nucleic Acids with Unusual Binding Properties.
Eugen Uhlmann, Anusch Peyman, Gerhard Breipohl, David W Will

Angew Chem Int Ed Engl· November 1998

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