Publications by authors named "David Y Thomas"

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Tankyrase-1 regulates RBP-mediated mRNA turnover to promote muscle fiber formation.
Souad Mubaid, Brenda Janice Sanchez, Rinad A Algehani, Viktoriia Skopenkova, Pauline Adjibade, David Y Thomas

Nucleic Acids Res· April 2024

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Ionocyte-Specific Regulation of Cystic Fibrosis Transmembrane Conductance Regulator.
Yukiko Sato, Dusik Kim, Mark J Turner, Yishan Luo, Syeda Sadaf Zehra Zaidi, David Y Thomas

Am J Respir Cell Mol Biol· September 2023

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N-glycosylation mediated folding and quality control in serine proteases of the hepsin family.
John J M Bergeron, David Y Thomas

FEBS J· August 2023

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Chronic obstructive pulmonary disease and the modulation of CFTR by acute exposure to cigarette smoke.
John W Hanrahan, Asmahan Abu-Arish, Francis H Wong, Mark J Turner, Graeme W Carlile, David Y Thomas

Am J Physiol Cell Physiol· November 2022

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Macrocycle-stabilization of its interaction with 14-3-3 increases plasma membrane localization and activity of CFTR.
Loes M Stevers, Madita Wolter, Graeme W Carlile, Dwight Macdonald, Luc Richard, David Y Thomas, Helmut Thomas

Nat Commun· June 2022

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The NSAID glafenine rescues class 2 CFTR mutants via cyclooxygenase 2 inhibition of the arachidonic acid pathway.
Graeme W Carlile, Qi Yang, Elizabeth Matthes, Jie Liao, Véronique Birault, David Y Thomas

Sci Rep· March 2022

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Rescue of Mutant CFTR Trafficking Defect by the Investigational Compound MCG1516A.
Miquéias Lopes-Pacheco, Mafalda Bacalhau, Sofia S Ramalho, Iris A L Silva, Filipa C Ferreira, David Y Thomas

Cells· January 2022

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Nonspecific binding of common anti-CFTR antibodies in ciliated cells of human airway epithelium.
Yukiko Sato, Kamila R Mustafina, Yishan Luo, Carolina Martini, David Y Thomas

Sci Rep· December 2021

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Phosphodiesterase 8A Regulates CFTR Activity in Airway Epithelial Cells.
Mark J Turner, Yukiko Sato, David Y Thomas, Kathy Abbott-Banner, John W Hanrahan

Cell Physiol Biochem· December 2021

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Cyclic nucleotide phosphodiesterase inhibitors as therapeutic interventions for cystic fibrosis.
Mark J Turner, Kathy Abbott-Banner, David Y Thomas, John W Hanrahan

Pharmacol Ther· August 2021

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Characterization of the mechanism of action of RDR01752, a novel corrector of F508del-CFTR.
Miquéias Lopes-Pacheco, Iris A L Silva, Mark J Turner, Graeme W Carlile, Elvira Sondo, David Y Thomas

Biochem Pharmacol· October 2020

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Combination of Selective PARP3 and PARP16 Inhibitory Analogues of Latonduine A Corrects F508del-CFTR Trafficking.
Ryan M Centko, Graeme W Carlile, Isabel Barne, Brian O Patrick, Polina Blagojevic, David Y Thomas

ACS Omega· October 2020

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Alternative Splicing of a Receptor Intracellular Domain Yields Different Ectodomain Conformations, Enabling Isoform-Selective Functional Ligands.
Fouad Brahimi, Alba Galan, Sean Jmaeff, Pablo F Barcelona, Nicolas De Jay, David Y Thomas

iScience· September 2020

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The dual phosphodiesterase 3/4 inhibitor RPL554 stimulates rare class III and IV CFTR mutants.
Mark J Turner, Yishan Luo, David Y Thomas, John W Hanrahan

Am J Physiol Lung Cell Mol Physiol· May 2020

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The anion transporter SLC26A9 localizes to tight junctions and is degraded by the proteasome when co-expressed with F508del-CFTR.
Yukiko Sato, David Y Thomas, John W Hanrahan

J Biol Chem· November 2019

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Cystic Fibrosis: Proteostatic correctors of CFTR trafficking and alternative therapeutic targets.
John W Hanrahan, Yukiko Sato, Graeme W Carlile, Gregor Jansen, Jason C Young, David Y Thomas

Expert Opin Ther Targets· August 2019

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Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation.
Marion Maurel, Joanna Obacz, Tony Avril, Yong-Ping Ding, Olga Papadodima, David Y Thomas

EMBO Mol Med· June 2019

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Variable Responses to CFTR Correctors : Estimating the Design Effect in Precision Medicine.
Elizabeth Matthes, Julie Goepp, Carolina Martini, Jiajie Shan, Jie Liao, David Y Thomas

Front Pharmacol· December 2018

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A novel triple combination of pharmacological chaperones improves F508del-CFTR correction.
Graeme W Carlile, Qi Yang, Elizabeth Matthes, Jie Liao, Stevo Radinovic, David Y Thomas

Sci Rep· July 2018

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Cigarette smoke activates CFTR through ROS-stimulated cAMP signaling in human bronchial epithelial cells.
Francis H Wong, Asmahan AbuArish, Elizabeth Matthes, Mark J Turner, Lana E Greene, David Y Thomas

Am J Physiol Cell Physiol· January 2018

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Proteomics Identifies Golgi phosphoprotein 3 (GOLPH3) with A Link Between Golgi Structure, Cancer, DNA Damage and Protection from Cell Death.
John J M Bergeron, Catherine E Au, David Y Thomas, Louis Hermo

Mol Cell Proteomics· December 2017

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An Official American Thoracic Society Workshop Report: Translational Research in Rare Respiratory Diseases.
Arnold S Kristof, Basil J Petrof, Qutayba Hamid, Martin Kolb, Jennifer S Landry, David Y Thomas

Ann Am Thorac Soc· August 2017

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Editorial.
David Y Thomas

J Taibah Univ Med Sci· June 2017

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Corrector combination therapies for F508del-CFTR.
John W Hanrahan, Elizabeth Matthes, Graeme Carlile, David Y Thomas

Curr Opin Pharmacol· June 2017

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Latonduine Analogs Restore F508del-Cystic Fibrosis Transmembrane Conductance Regulator Trafficking through the Modulation of Poly-ADP Ribose Polymerase 3 and Poly-ADP Ribose Polymerase 16 Activity.
Graeme W Carlile, Renaud Robert, Elizabeth Matthes, Qi Yang, Roberto Solari, David Y Thomas

Mol Pharmacol· August 2016

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