Publications by authors named "Dax Fu"

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Cell-Surface ZnT8 Antibody Prevents and Reverses Autoimmune Diabetes in Mice.
Devi Kasinathan, Zheng Guo, Dylan C Sarver, G William Wong, Shumei Yun, Dax Fu

Diabetes· May 2024

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Cell-Surface Autoantibody Targets Zinc Transporter-8 (ZnT8) for In Vivo β-Cell Imaging and Islet-Specific Therapies.
Zheng Guo, Devi Kasinathan, Chengfeng Merriman, Maki Nakayama, Hua Li, Dax Fu

Diabetes· February 2023

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Novel autoantibodies to the β-cell surface epitopes of ZnT8 in patients progressing to type-1 diabetes.
Yong Gu, Chengfeng Merriman, Zheng Guo, Xiaofan Jia, Janet Wenzlau, Dax Fu

J Autoimmun· August 2021

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Zinc transporters and their functional integration in mammalian cells.
Taiho Kambe, Kathryn M Taylor, Dax Fu

J Biol Chem· July 2021

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Down-regulation of the islet-specific zinc transporter-8 (ZnT8) protects human insulinoma cells against inflammatory stress.
Chengfeng Merriman, Dax Fu

J Biol Chem· November 2019

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Water molecules mediate zinc mobility in the bacterial zinc diffusion channel ZIPB.
Sayan Gupta, Chengfeng Merriman, Christopher J Petzold, Corie Y Ralston, Dax Fu

J Biol Chem· September 2019

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Induction of the metal transporter ZIP8 by interferon gamma in intestinal epithelial cells: Potential role of metal dyshomeostasis in Crohn's disease.
Joanna M P Melia, Ruxian Lin, Ramnik J Xavier, Richard B Thompson, Dax Fu

Biochem Biophys Res Commun· July 2019

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Highly specific monoclonal antibodies for allosteric inhibition and immunodetection of the human pancreatic zinc transporter ZnT8.
Chengfeng Merriman, Hua Li, Huilin Li, Dax Fu

J Biol Chem· October 2018

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A subclass of serum anti-ZnT8 antibodies directed to the surface of live pancreatic β-cells.
Chengfeng Merriman, Qiong Huang, Wei Gu, Liping Yu, Dax Fu

J Biol Chem· January 2018

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Proteoliposome-based full-length ZnT8 self-antigen for type 1 diabetes diagnosis on a plasmonic platform.
Hao Wan, Chengfeng Merriman, Mark A Atkinson, Clive H Wasserfall, Kieran M Mcgrail, Dax Fu

Proc Natl Acad Sci U S A· September 2017

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Coupling of Insulin Secretion and Display of a Granule-resident Zinc Transporter ZnT8 on the Surface of Pancreatic Beta Cells.
Qiong Huang, Chengfeng Merriman, Hao Zhang, Dax Fu

J Biol Chem· March 2017

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Lipid-tuned Zinc Transport Activity of Human ZnT8 Protein Correlates with Risk for Type-2 Diabetes.
Chengfeng Merriman, Qiong Huang, Guy A Rutter, Dax Fu

J Biol Chem· December 2016

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The PP-motif in luminal loop 2 of ZnT transporters plays a pivotal role in TNAP activation.
Shigeyuki Fujimoto, Tokuji Tsuji, Takashi Fujiwara, Taka-Aki Takeda, Chengfeng Merriman, Ayako Fukunaka, Dax Fu, Kazuhisa Fukue

Biochem J· September 2016

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Visualizing the kinetic power stroke that drives proton-coupled zinc(II) transport.
Sayan Gupta, Jin Chai, Jie Cheng, Rhijuta D'Mello, Mark R Chance, Dax Fu

Nature· August 2014

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Intact functional fourteen-subunit respiratory membrane-bound [NiFe]-hydrogenase complex of the hyperthermophilic archaeon Pyrococcus furiosus.
Patrick M McTernan, Sanjeev K Chandrayan, Chang-Hao Wu, Brian J Vaccaro, W Andrew Lancaster, Dax Fu

J Biol Chem· July 2014

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Metalloproteomics: challenges and prospective for clinical research applications.
Dax Fu, Lydia Finney

Expert Rev Proteomics· February 2014

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Histidine pairing at the metal transport site of mammalian ZnT transporters controls Zn2+ over Cd2+ selectivity.
Eitan Hoch, Wei Lin, Jin Chai, Michal Hershfinkel, Dax Fu

Proc Natl Acad Sci U S A· May 2012

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Selective electrodiffusion of zinc ions in a Zrt-, Irt-like protein, ZIPB.
Wei Lin, Jin Chai, James Love, Dax Fu

J Biol Chem· December 2010

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Structural basis for autoregulation of the zinc transporter YiiP.
Min Lu, Jin Chai, Dax Fu

Nat Struct Mol Biol· October 2009

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The structural basis of water permeation and proton exclusion in aquaporins.
Dax Fu, Min Lu

Mol Membr Biol· November 2007

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Structure of the zinc transporter YiiP.
Min Lu, Dax Fu

Science· September 2007

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Binding and transport of metal ions at the dimer interface of the Escherichia coli metal transporter YiiP.
Yinan Wei, Dax Fu

J Biol Chem· August 2006

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Crystal structure of AqpZ tetramer reveals two distinct Arg-189 conformations associated with water permeation through the narrowest constriction of the water-conducting channel.
Jiansheng Jiang, Brenda V Daniels, Dax Fu

J Biol Chem· January 2006

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Selective metal binding to a membrane-embedded aspartate in the Escherichia coli metal transporter YiiP (FieF).
Yinan Wei, Dax Fu

J Biol Chem· October 2005

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Oligomeric state of the Escherichia coli metal transporter YiiP.
Yinan Wei, Huilin Li, Dax Fu

J Biol Chem· September 2004

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