Publications by authors named "Deborah Smithen"

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Toward the Scale-Up of a Bicyclic Homopiperazine via Schmidt Rearrangement and Photochemical Oxaziridine Rearrangement in Continuous-Flow.
Michael Brown, Mohammed Aljarah, Hannah Asiki, Leo M H Leung, Deborah A Smithen

Org Process Res Dev· January 2021

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Bis[pyrrolyl Ru(ii)] triads: a new class of photosensitizers for metal-organic photodynamic therapy.
Deborah A Smithen, Susan Monro, Mitch Pinto, John Roque, Roberto M Diaz-Rodriguez

Chem Sci· November 2020

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2-Aminomethylene-5-sulfonylthiazole Inhibitors of Lysyl Oxidase (LOX) and LOXL2 Show Significant Efficacy in Delaying Tumor Growth.
Deborah A Smithen, Leo M H Leung, Mairi Challinor, Rae Lawrence, HaoRan Tang

J Med Chem· March 2020

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Anti-metastatic Inhibitors of Lysyl Oxidase (LOX): Design and Structure-Activity Relationships.
Leo Leung, Dan Niculescu-Duvaz, Deborah Smithen, Filipa Lopes, Cedric Callens

J Med Chem· June 2019

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Synthesis and Photobiological Activity of Ru(II) Dyads Derived from Pyrrole-2-carboxylate Thionoesters.
Deborah A Smithen, Huimin Yin, Michael H R Beh, Marc Hetu, T Stanley Cameron

Inorg Chem· April 2017

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Probing the hydrolytic reactivity of 2-difluoromethyl pyrroles.
Jennifer A Melanson, Carlotta Figliola, Deborah A Smithen, Aleksandra K Kajetanowicz, Alison Thompson

Org Biomol Chem· December 2016

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Mechanistic evaluation of a nucleoside tetraphosphate with a thymidylyltransferase.
Stephanie M Forget, Deborah A Smithen, Alison Jee, David L Jakeman

Biochemistry· March 2015

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Polyphosphate-containing bisubstrate analogues as inhibitors of a bacterial cell wall thymidylyltransferase.
Deborah A Smithen, Stephanie M Forget, Nicole E McCormick, Raymond T Syvitski, David L Jakeman

Org Biomol Chem· March 2015

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Eight-membered ring-containing jadomycins: implications for non-enzymatic natural products biosynthesis.
Andrew W Robertson, Camilo F Martinez-Farina, Deborah A Smithen, Huimin Yin, Susan Monro

J Am Chem Soc· March 2015

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Synthesis and antimalarial activity of prodigiosenes.
Estelle Marchal, Deborah A Smithen, Md Imam Uddin, Andrew W Robertson, David L Jakeman

Org Biomol Chem· June 2014

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Investigations regarding the utility of prodigiosenes to treat leukemia.
Deborah A Smithen, A Michael Forrester, Dale P Corkery, Graham Dellaire, Julie Colpitts

Org Biomol Chem· January 2013

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Asymmetric α-oxyacylation of cyclic ketones.
Deborah A Smithen, Christopher J Mathews, Nicholas C O Tomkinson

Org Biomol Chem· May 2012

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Use of F-BODIPYs as a protection strategy for dipyrrins: optimization of BF(2) removal.
Deborah A Smithen, Alexander E G Baker, Matthew Offman, Sarah M Crawford, T Stanley Cameron

J Org Chem· April 2012

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An improved method for the synthesis of F-BODIPYs from dipyrrins and bis(dipyrrin)s.
Travis Lundrigan, Alexander E G Baker, Lauren E Longobardi, Tabitha E Wood, Deborah A Smithen

Org Lett· April 2012

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One-pot synthesis of asymmetric annulated bis(pyrrole)s.
Deborah A Smithen, T Stanley Cameron, Alison Thompson

Org Lett· November 2011

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