Publications by authors named "Deepa Murugesh"

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Regional and Sexual Dimorphism in Murine Skeletal Responses to Osteocytic HIF Pathway Modulation.
Sarah V Mendoza, Deepa K Murugesh, Benjamin Osipov, Blaine A Christiansen, Gabriela G Loots

J Orthop Res· January 2026

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Early immune response to is characterized by robust neutrophil and fibrotic macrophage recruitment and differentiation.
Nadia Miranda, Oscar A Davalos, Aimy Sebastian, Margarita V Rangel, Nicole F Leon, Deepa K Murugesh

Microbiol Spectr· September 2025

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Spatiotemporal analysis of lung immune dynamics in lethal infection.
Oscar A Davalos, Aimy Sebastian, Nicole F Leon, Margarita V Rangel, Nadia Miranda, Deepa K Murugesh

mBio· May 2025

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Osteocytic oxygen sensing: Distinct impacts of VHL and HIF-2alpha on bone integrity.
Sarah V Mendoza, Kristina V Wells, Deepa K Murugesh, Nicholas R Hum, Aimy Sebastian

Bone· March 2025

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Improved Zika virus plaque assay using Vero/TMPRSS2 cell line.
Olukunle O Oluwasemowo, Monica E Graham, Deepa K Murugesh, Monica K Borucki

Microbiol Spectr· January 2025

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CD206+ Trem2+ macrophage accumulation in the murine knee joint after injury is associated with protection against post-traumatic osteoarthritis in MRL/MpJ mice.
Jillian L McCool, Aimy Sebastian, Nicholas R Hum, Stephen P Wilson, Oscar A Davalos, Deepa K Murugesh

PLoS One· January 2025

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Altered post-fracture systemic bone loss in a mouse model of osteocyte dysfunction.
Benjamin Osipov, Armaun J Emami, Hailey C Cunningham, Sophie Orr, Yu-Yang Lin, Deepa K Murugesh

JBMR Plus· December 2024

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Mef2c regulates bone mass through Sost-dependent and -independent mechanisms.
Cesar Morfin, Aimy Sebastian, Stephen P Wilson, Beheshta Amiri, Deepa K Murugesh

Bone· February 2024

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Antibiotic Treatment Prior to Injury Abrogates the Detrimental Effects of LPS in Mice Susceptible to Osteoarthritis Development.
Melanie E Mendez, Deepa K Murugesh, Blaine A Christiansen, Gabriela G Loots

JBMR Plus· August 2023

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Degradation-Resistant Hypoxia Inducible Factor-2α in Murine Osteocytes Promotes a High Bone Mass Phenotype.
Sarah V Mendoza, Deepa K Murugesh, Blaine A Christiansen, Zoe O Genetos, Gabriela G Loots

JBMR Plus· April 2023

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Differential bone adaptation to mechanical unloading and reloading in young, old, and osteocyte deficient mice.
Hailey C Cunningham, Sophie Orr, Deepa K Murugesh, Allison W Hsia, Benjamin Osipov

Bone· February 2023

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Single-cell RNA-Seq reveals changes in immune landscape in post-traumatic osteoarthritis.
Aimy Sebastian, Nicholas R Hum, Jillian L McCool, Stephen P Wilson, Deepa K Murugesh

Front Immunol· August 2022

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Preexisting Type 1 Diabetes Mellitus Blunts the Development of Posttraumatic Osteoarthritis.
Naiomy D Rios-Arce, Deepa K Murugesh, Nicholas R Hum, Aimy Sebastian, Elias H Jbeily

JBMR Plus· May 2022

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Sclerostin Depletion Induces Inflammation in the Bone Marrow of Mice.
Cristine Donham, Betsabel Chicana, Alexander G Robling, Asmaa Mohamed, Sonny Elizaldi, Deepa K Murugesh

Int J Mol Sci· August 2021

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Discovery of Small-Molecule Inhibitors of SARS-CoV-2 Proteins Using a Computational and Experimental Pipeline.
Edmond Y Lau, Oscar A Negrete, W F Drew Bennett, Brian J Bennion, Monica Borucki, Deepa K Murugesh

Front Mol Biosci· July 2021

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Single-Cell RNA-Seq Reveals Transcriptomic Heterogeneity and Post-Traumatic Osteoarthritis-Associated Early Molecular Changes in Mouse Articular Chondrocytes.
Aimy Sebastian, Jillian L McCool, Nicholas R Hum, Deepa K Murugesh, Stephen P Wilson

Cells· June 2021

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LPS-Induced Inflammation Prior to Injury Exacerbates the Development of Post-Traumatic Osteoarthritis in Mice.
Melanie E Mendez, Aimy Sebastian, Deepa K Murugesh, Nicholas R Hum, Jillian L McCool

J Bone Miner Res· November 2020

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Antibiotic Treatment Prior to Injury Improves Post-Traumatic Osteoarthritis Outcomes in Mice.
Melanie E Mendez, Deepa K Murugesh, Aimy Sebastian, Nicholas R Hum, Summer A McCloy

Int J Mol Sci· September 2020

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Manipulation of the Gut Microbiome Alters Acetaminophen Biodisposition in Mice.
Michael A Malfatti, Edward A Kuhn, Deepa K Murugesh, Melanie E Mendez, Nicholas Hum

Sci Rep· March 2020

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Global Gene Expression Analysis Identifies Age-Related Differences in Knee Joint Transcriptome during the Development of Post-Traumatic Osteoarthritis in Mice.
Aimy Sebastian, Deepa K Murugesh, Melanie E Mendez, Nicholas R Hum, Naiomy D Rios-Arce

Int J Mol Sci· January 2020

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Sostdc1 Regulates NK Cell Maturation and Cytotoxicity.
Alberto J Millan, Sonny R Elizaldi, Eric M Lee, Jeffrey O Aceves, Deepa Murugesh

J Immunol· April 2019

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Vhl deficiency in osteocytes produces high bone mass and hematopoietic defects.
Gabriela G Loots, Alexander G Robling, Jiun C Chang, Deepa K Murugesh, Jamila Bajwa

Bone· November 2018

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Conditional Deletion of Sost in MSC-Derived Lineages Identifies Specific Cell-Type Contributions to Bone Mass and B-Cell Development.
Cristal S Yee, Jennifer O Manilay, Jiun C Chang, Nicholas R Hum, Deepa K Murugesh

J Bone Miner Res· October 2018

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Global gene expression analysis identifies Mef2c as a potential player in Wnt16-mediated transcriptional regulation.
Aimy Sebastian, Nicholas R Hum, Cesar Morfin, Deepa K Murugesh, Gabriela G Loots

Gene· October 2018

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Comparative Transcriptomics Identifies Novel Genes and Pathways Involved in Post-Traumatic Osteoarthritis Development and Progression.
Aimy Sebastian, Jiun C Chang, Melanie E Mendez, Deepa K Murugesh, Sarah Hatsell

Int J Mol Sci· September 2018

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