Publications by authors named "Deepak Perumal"

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Pharmacokinetics and safety of subcutaneous nivolumab: results from the phase I/II CheckMate 8KX study.
Sara Lonardi, Iwona Ługowska, Anne O'Donnell, Christopher Jackson, Loes Maria Latten-Jansen, Deepak Perumal

J Immunother Cancer· October 2025

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Nivolumab, Pomalidomide, and Elotuzumab Combination Regimens for Treatment of Relapsed and Refractory Multiple Myeloma: Results from the Phase 3 CheckMate 602 Study.
Albert Oriol, Roman Hájek, Ivan Spicka, Irwindeep Sandhu, Yael C Cohen, Deepak Perumal

Clin Lymphoma Myeloma Leuk· October 2024

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High Dimensional Immune Profiling of Smoldering Multiple Myeloma Distinguishes Distinct Tumor Microenvironments.
Nicolas Fernandez, Deepak Perumal, Adeeb Rahman, Seunghee Kim-Schulze, Jen Yesil

Clin Lymphoma Myeloma Leuk· November 2022

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Subtype-specific and co-occurring genetic alterations in B-cell non-Hodgkin lymphoma.
Man Chun John Ma, Saber Tadros, Alyssa Bouska, Tayla Heavican, Haopeng Yang, Deepak Perumal

Haematologica· March 2022

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MAGE-A inhibit apoptosis and promote proliferation in multiple myeloma through regulation of BIM and p21.
Anna Huo-Chang Mei, Kaity Tung, Jessie Han, Deepak Perumal, Alessandro Laganà

Oncotarget· February 2020

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Mutation-derived Neoantigen-specific T-cell Responses in Multiple Myeloma.
Deepak Perumal, Naoko Imai, Alessandro Laganà, John Finnigan, David Melnekoff

Clin Cancer Res· January 2020

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Precision Medicine for Relapsed Multiple Myeloma on the Basis of an Integrative Multiomics Approach.
Alessandro Laganà, Itai Beno, David Melnekoff, Violetta Leshchenko, Deepu Madduri, Deepak Perumal

JCO Precis Oncol· August 2018

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SOX11 augments BCR signaling to drive MCL-like tumor development.
Pei-Yu Kuo, Shashidhar S Jatiani, Adeeb H Rahman, Donna Edwards, Zewei Jiang, Deepak Perumal

Blood· May 2018

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A phase 2 study of panobinostat with lenalidomide and weekly dexamethasone in myeloma.
Ajai Chari, Hearn J Cho, Amishi Dhadwal, Gillian Morgan, Lisa La, Deepak Perumal

Blood Adv· August 2017

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Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia.
Andriana G Kotini, Chan-Jung Chang, Arthur Chow, Han Yuan, Tzu-Chieh Ho, Deepak Perumal

Cell Stem Cell· March 2017

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Dual Targeting of CDK4 and ARK5 Using a Novel Kinase Inhibitor ON123300 Exerts Potent Anticancer Activity against Multiple Myeloma.
Deepak Perumal, Pei-Yu Kuo, Violetta V Leshchenko, Zewei Jiang, Sai Krishna Athaluri Divakar

Cancer Res· March 2016

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Gli1-Mediated Regulation of Sox2 Facilitates Self-Renewal of Stem-Like Cells and Confers Resistance to EGFR Inhibitors in Non-Small Cell Lung Cancer.
Namrata Bora-Singhal, Deepak Perumal, Jonathan Nguyen, Srikumar Chellappan

Neoplasia· July 2015

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YAP1 Regulates OCT4 Activity and SOX2 Expression to Facilitate Self-Renewal and Vascular Mimicry of Stem-Like Cells.
Namrata Bora-Singhal, Jonathan Nguyen, Courtney Schaal, Deepak Perumal, Sandeep Singh

Stem Cells· June 2015

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Nicotinic acetylcholine receptors induce c-Kit ligand/Stem Cell Factor and promote stemness in an ARRB1/ β-arrestin-1 dependent manner in NSCLC.
Deepak Perumal, Smitha Pillai, Jonathan Nguyen, Courtney Schaal, Domenico Coppola

Oncotarget· November 2014

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Nicotine-mediated invasion and migration of non-small cell lung carcinoma cells by modulating STMN3 and GSPT1 genes in an ID1-dependent manner.
Sajitha Nair, Namrata Bora-Singhal, Deepak Perumal, Srikumar Chellappan

Mol Cancer· July 2014

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A novel five gene signature derived from stem-like side population cells predicts overall and recurrence-free survival in NSCLC.
Deepak Perumal, Sandeep Singh, Sean J Yoder, Gregory C Bloom, Srikumar P Chellappan

PLoS One· February 2013

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Cloning and targeted disruption of two lipopolysaccharide biosynthesis genes, kdsA and waaG, of Pseudomonas aeruginosa PAO1 by site-directed mutagenesis.
Deepak Perumal, Kishore R Sakharkar, Thean Hock Tang, Vincent T K Chow, Chu Sing Lim

J Mol Microbiol Biotechnol· June 2011

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Targeting multiple targets in Pseudomonas aeruginosa PAO1 using flux balance analysis of a reconstructed genome-scale metabolic network.
Deepak Perumal, Areejit Samal, Kishore R Sakharkar, Meena K Sakharkar

J Drug Target· January 2011

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A Comparative Study of Metabolic Network Topology between a Pathogenic and a Non-Pathogenic Bacterium for Potential Drug Target Identification.
Deepak Perumal, Chu Sing Lim, Meena K Sakharkar

Summit Transl Bioinform· March 2009

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A combined computational-experimental analyses of selected metabolic enzymes in Pseudomonas species.
Deepak Perumal, Chu Sing Lim, Vincent T K Chow, Kishore R Sakharkar, Meena K Sakharkar

Int J Biol Sci· September 2008

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Differential genome analyses of metabolic enzymes in Pseudomonas aeruginosa for drug target identification.
Deepak Perumal, Chu Sing Lim, Kishore R Sakharkar, Meena K Sakharkar

In Silico Biol· April 2008

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