Publications by authors named "Srikumar Chellappan"

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TBK1 Reprograms Metabolism in Breast Cancer: An Integrated Omics Approach.
Meenu Maan, Neha Jaiswal, Min Liu, Harold I Saavedra, Srikumar P Chellappan

J Proteome Res· January 2025

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CDK7 and CDK9 inhibition interferes with transcription, translation, and stemness, and induces cytotoxicity in GBM irrespective of temozolomide sensitivity.
Isha Bhutada, Fatema Khambati, Shi-Yuan Cheng, Deanna M Tiek, Derek Duckett, Srikumar P Chellappan

Neuro Oncol· January 2024

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HDAC11 activity contributes to MEK inhibitor escape in uveal melanoma.
Sathya Neelature Sriramareddy, Fernanda Faião-Flores, Michael F Emmons, Biswarup Saha, Srikumar Chellappan

Cancer Gene Ther· December 2022

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Ethnic and racial-specific differences in levels of centrosome-associated mitotic kinases, proliferative and epithelial-to-mesenchymal markers in breast cancers.
Yainyrette Rivera-Rivera, Geraldine Vargas, Neha Jaiswal, Angel Núñez-Marrero, Jiannong Li, Srikumar P Chellappan

Cell Div· December 2022

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Smoking Cessation after Cancer Diagnosis and Enhanced Therapy Response: Mechanisms and Significance.
Srikumar Chellappan

Curr Oncol· December 2022

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A Novel PHD2/VHL-mediated Regulation of YAP1 Contributes to VEGF Expression and Angiogenesis.
Namrata Bora-Singhal, Biswarup Saha, Durairaj Mohankumar, Jaya Padmanabhan, Domenico Coppola, Srikumar Chellappan

Cancer Res Commun· July 2022

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Lifetime ovulatory years and ovarian cancer gene expression profiles.
Naoko Sasamoto, Paul A Stewart, Tianyi Wang, Sean J Yoder, Srikumar Chellappan

J Ovarian Res· May 2022

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Inhibitors Targeting CDK9 Show High Efficacy against Osimertinib and AMG510 Resistant Lung Adenocarcinoma Cells.
Jaya Padmanabhan, Biswarup Saha, Chase Powell, Qianxing Mo, Bradford A Perez, Srikumar Chellappan

Cancers (Basel)· August 2021

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The Nek2 centrosome-mitotic kinase contributes to the mesenchymal state, cell invasion, and migration of triple-negative breast cancer cells.
Yainyrette Rivera-Rivera, Mihaela Marina, Shirley Jusino, Miyoung Lee, Jaleisha Vélez Velázquez, Srikumar P Chellappan

Sci Rep· April 2021

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Tank Binding Kinase 1 modulates spindle assembly checkpoint components to regulate mitosis in breast and lung cancer cells.
Meenu Maan, Neha Jaiswal Agrawal, Jaya Padmanabhan, Christelle Colin Leitzinger, Yainyrette Rivera-Rivera, Srikumar P Chellappan

Biochim Biophys Acta Mol Cell Res· March 2021

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Novel HDAC11 inhibitors suppress lung adenocarcinoma stem cell self-renewal and overcome drug resistance by suppressing Sox2.
Namrata Bora-Singhal, Durairaj Mohankumar, Biswarup Saha, Christelle M Colin, Jennifer Y Lee, Srikumar Chellappan

Sci Rep· March 2020

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Chromatin protein PC4 is downregulated in breast cancer to promote disease progression: Implications of miR-29a.
Sweta Sikder, Sujata Kumari, Manoj Kumar, Shrinka Sen, Namrata Bora Singhal, Srikumar Chellappan

Oncotarget· December 2019

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HDAC Inhibition Enhances the Efficacy of MEK Inhibitor Therapy in Uveal Melanoma.
Fernanda Faião-Flores, Michael F Emmons, Michael A Durante, Fumi Kinose, Biswarup Saha, Srikumar P Chellappan

Clin Cancer Res· September 2019

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Fascin Controls Metastatic Colonization and Mitochondrial Oxidative Phosphorylation by Remodeling Mitochondrial Actin Filaments.
Shengchen Lin, Chongbiao Huang, Venugopal Gunda, Jianwei Sun, Srikumar P Chellappan

Cell Rep· September 2019

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Cationic lipoplexes for treatment of cancer stem cell-derived murine lung tumors.
Terrick Andey, Namrata Bora-Singhal, Srikumar P Chellappan, Mandip Singh

Nanomedicine· June 2019

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Fendiline Enhances the Cytotoxic Effects of Therapeutic Agents on PDAC Cells by Inhibiting Tumor-Promoting Signaling Events: A Potential Strategy to Combat PDAC.
Marwa Alhothali, Mevin Mathew, Geeta Iyer, Harshani R Lawrence, Shengyu Yang, Srikumar Chellappan

Int J Mol Sci· May 2019

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Regulation of Sox2 and stemness by nicotine and electronic-cigarettes in non-small cell lung cancer.
Courtney M Schaal, Namrata Bora-Singhal, Durairaj Mohan Kumar, Srikumar P Chellappan

Mol Cancer· October 2018

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Nicotine-Mediated Regulation of Nicotinic Acetylcholine Receptors in Non-Small Cell Lung Adenocarcinoma by E2F1 and STAT1 Transcription Factors.
Courtney Schaal, Srikumar Chellappan

PLoS One· July 2017

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In vitro replication assay with mammalian cell extracts.
Wasia Rizwani, Srikumar P Chellappan

Methods Mol Biol· December 2015

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Chromatin immunoprecipitation assays: analyzing transcription factor binding and histone modifications in vivo.
Smitha Pillai, Piyali Dasgupta, Srikumar P Chellappan

Methods Mol Biol· December 2015

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ChIP on chip and ChIP-Seq assays: genome-wide analysis of transcription factor binding and histone modifications.
Smitha Pillai, Srikumar P Chellappan

Methods Mol Biol· December 2015

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Tank binding kinase 1 is a centrosome-associated kinase necessary for microtubule dynamics and mitosis.
Smitha Pillai, Jonathan Nguyen, Joseph Johnson, Eric Haura, Domenico Coppola, Srikumar Chellappan

Nat Commun· December 2015

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Fendiline inhibits proliferation and invasion of pancreatic cancer cells by interfering with ADAM10 activation and β-catenin signaling.
Neha Woods, Jose Trevino, Domenico Coppola, Srikumar Chellappan, Shengyu Yang

Oncotarget· November 2015

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The Role of nAChR and Calcium Signaling in Pancreatic Cancer Initiation and Progression.
Courtney Schaal, Jaya Padmanabhan, Srikumar Chellappan

Cancers (Basel)· July 2015

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Gli1-Mediated Regulation of Sox2 Facilitates Self-Renewal of Stem-Like Cells and Confers Resistance to EGFR Inhibitors in Non-Small Cell Lung Cancer.
Namrata Bora-Singhal, Deepak Perumal, Jonathan Nguyen, Srikumar Chellappan

Neoplasia· July 2015

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