Publications by authors named "Deepthi Ashok"

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Innate immune activation and mitochondrial ROS induce acute and persistent cardiac conduction system dysfunction after COVID-19.
Deepthi Ashok, Ting Liu, Misato Nakanishi-Koakutsu, Joseph Criscione, Meghana Prakash

JCI Insight· December 2025

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Loss of O-GlcNAcylation in cardiac myocytes triggers the integrated stress response, contributing to heart failure.
Kyriakos N Papanicolaou, Wenxi Zhang, Aidan J Dunphy, Justin C Zhong, Clara Y Cho, Deepthi Ashok

J Biol Chem· October 2025

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Mitochondrial Membrane Potential and Lactate Dehydrogenase Activity in a Model of Acute In Vitro Ischemia/Reperfusion Injury.
Deepthi Ashok, Haley Garbus, Obialunanma V Ebenebe

Methods Mol Biol· December 2024

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Innate Immune Activation and Mitochondrial ROS Invoke Persistent Cardiac Conduction System Dysfunction after COVID-19.
Deepthi Ashok, Ting Liu, Joseph Criscione, Meghana Prakash, Byunggik Kim

bioRxiv· January 2024

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Mitochondrial membrane potential instability on reperfusion after ischemia does not depend on mitochondrial Ca uptake.
Deepthi Ashok, Kyriakos Papanicolaou, Agnieszka Sidor, Michelle Wang, Soroosh Solhjoo

J Biol Chem· June 2023

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Inhibiting O-GlcNAcylation impacts p38 and Erk1/2 signaling and perturbs cardiomyocyte hypertrophy.
Kyriakos N Papanicolaou, Jessica Jung, Deepthi Ashok, Wenxi Zhang, Amir Modaressanavi

J Biol Chem· March 2023

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Inhibition of phosphodiesterase type 9 reduces obesity and cardiometabolic syndrome in mice.
Sumita Mishra, Nandhini Sadagopan, Brittany Dunkerly-Eyring, Susana Rodriguez, Dylan C Sarver, Deepthi Ashok

J Clin Invest· November 2021

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MitoWave: Spatiotemporal analysis of mitochondrial membrane potential fluctuations during I/R.
Deepthi Ashok, Brian O'Rourke

Biophys J· August 2021

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Mitochondrial Ca in heart failure: Not enough or too much?
Brian O'Rourke, Deepthi Ashok, Ting Liu

J Mol Cell Cardiol· February 2021

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Nuclear-mitochondrial communication involving miR-181c plays an important role in cardiac dysfunction during obesity.
Barbara Roman, Pawandeep Kaur, Deepthi Ashok, Mark Kohr, Roopa Biswas

J Mol Cell Cardiol· July 2020

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Global knockout of ROMK potassium channel worsens cardiac ischemia-reperfusion injury but cardiomyocyte-specific knockout does not: Implications for the identity of mitoKATP.
Kyriakos N Papanicolaou, Deepthi Ashok, Ting Liu, Tyler M Bauer, Junhui Sun

J Mol Cell Cardiol· February 2020

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Reactive oxygen species production and mitochondrial dysfunction in white blood cells are not valid biomarkers of ageing in the very old.
Laura Wiley, Deepthi Ashok, Carmen Martin-Ruiz, Duncan C S Talbot, Joanna Collerton

PLoS One· March 2016

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Novel inhibitors of mitochondrial sn-glycerol 3-phosphate dehydrogenase.
Adam L Orr, Deepthi Ashok, Melissa R Sarantos, Ryan Ng, Tong Shi

PLoS One· January 2015

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Frailty and mortality are not influenced by mitochondrial DNA haplotypes in the very old.
Joanna Collerton, Deepthi Ashok, Carmen Martin-Ruiz, Angela Pyle, Gavin Hudson

Neurobiol Aging· December 2013

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Inhibitors of ROS production by the ubiquinone-binding site of mitochondrial complex I identified by chemical screening.
Adam L Orr, Deepthi Ashok, Melissa R Sarantos, Tong Shi, Robert E Hughes

Free Radic Biol Med· December 2013

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High throughput microplate respiratory measurements using minimal quantities of isolated mitochondria.
George W Rogers, Martin D Brand, Susanna Petrosyan, Deepthi Ashok, Alvaro A Elorza

PLoS One· December 2011

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