Publications by authors named "Defu Zeng"

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New approach targets key traffickers in the fibrosis network.
Defu Zeng

Blood· December 2025

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Intestinal epithelial Ceacam1 deficiency prevents steroid-refractory acute gut graft-versus-host disease.
Qingxiao Song, Moqian Zheng, Qinjian Li, Xiwei Wu, Boxi Lin, Defu Zeng

JCI Insight· September 2025

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The opposite impact of Janus kinase inhibitor Ruxolitinib on the function of bone marrow mesenchymal stem cells and immune cells in acute GVHD recipients.
Defu Zeng

Blood Sci· October 2023

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Chronic GvHD NIH Consensus Project Biology Task Force: evolving path to personalized treatment of chronic GvHD.
Nataliya P Buxbaum, Gerard Socié, Geoffrey R Hill, Kelli P A MacDonald, Victor Tkachev, Defu Zeng

Blood Adv· September 2023

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Donor programmed cell death 1 ligand 1 is required for organ transplant tolerance in major histocompatibility complex-mismatched mixed chimeras although programmed cell death 1 ligand 1 and major histocompatibility complex class II are not required for inducing chimerism.
Yaxun Huang, Xiwei Wu, Shanshan Tang, Huiqing Wu, Ubaydah Nasri, Defu Zeng

Am J Transplant· August 2023

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Donor T cell STAT3 deficiency enables tissue PD-L1-dependent prevention of graft-versus-host disease while preserving graft-versus-leukemia activity.
Qinjian Li, Xiaoqi Wang, Qingxiao Song, Shijie Yang, Xiwei Wu, Defu Zeng

J Clin Invest· August 2023

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Engineering CpG island DNA methylation in pluripotent cells through synthetic CpG-free ssDNA insertion.
Joshua Tompkins, Elizabeth Lizhar, Alireza Shokrani, Xiwei Wu, Jordan Berley, Defu Zeng

Cell Rep Methods· May 2023

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Blockade of trans PD-L1 interaction with CD80 augments antitumor immunity.
Yuankun Zhang, Qingxiao Song, Kaniel Cassady, Michael Lee, Haidong Tang, Defu Zeng

Proc Natl Acad Sci U S A· April 2023

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Th17 Cell-Derived Amphiregulin Promotes Colitis-Associated Intestinal Fibrosis Through Activation of mTOR and MEK in Intestinal Myofibroblasts.
Xiaojing Zhao, Wenjing Yang, Tianming Yu, Yu Yu, Xiufang Cui, Defu Zeng

Gastroenterology· January 2023

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Trafficking between clonally related peripheral T-helper cells and tissue-resident T-helper cells in chronic GVHD.
Xiaohui Kong, Xiwei Wu, Bixin Wang, Deye Zeng, Kaniel Cassady, Defu Zeng

Blood· December 2022

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MOF-Derived CoO Nanoparticles Catalyzing Hydrothermal Deoxygenation of Fatty Acids for Alkane Production.
Defu Zeng, Yalin Li, Tao Xia, Fuyi Cui, Jing Zhang

ACS Omega· September 2022

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The Investigation on Nosocomial Infection of Acinetobacter baumannii and the Clinical Analysis of Sequential Therapy of Cefoperazone/Sulbactam Sodium for Intracranial Infection.
Zezhong Xiong, Defu Zeng, Shilong Shen, Zhibang Han

Comput Math Methods Med· August 2022

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Retention of Donor T Cells in Lymphohematopoietic Tissue and Augmentation of Tissue PD-L1 Protection for Prevention of GVHD While Preserving GVL Activity.
Qingxiao Song, Ubaydah Nasri, Ryotaro Nakamura, Paul J Martin, Defu Zeng

Front Immunol· June 2022

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Steroid-Refractory Gut Graft-Versus-Host Disease: What We Have Learned From Basic Immunology and Experimental Mouse Model.
Qingxiao Song, Ubaydah Nasri, Defu Zeng

Front Immunol· May 2022

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microRNA-142 guards against autoimmunity by controlling Treg cell homeostasis and function.
Wei-Le Wang, Ching Ouyang, Natalie M Graham, Yuankun Zhang, Kaniel Cassady, Defu Zeng

PLoS Biol· February 2022

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Murine Models Provide New Insights Into Pathogenesis of Chronic Graft--Host Disease in Humans.
Qingxiao Song, Xiaohui Kong, Paul J Martin, Defu Zeng

Front Immunol· December 2021

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Syntaxin 4 Enrichment in β-Cells Prevents Conversion to Autoimmune Diabetes in Non-Obese Diabetic (NOD) Mice.
Eunjin Oh, Erika M McCown, Miwon Ahn, Pablo A Garcia, Sergio Branciamore, De-Fu Zeng

Diabetes· December 2021

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Tolerogenic anti-IL-2 mAb prevents graft-versus-host disease while preserving strong graft-versus-leukemia activity.
Qingxiao Song, Xiaoning Wang, Xiwei Wu, Hanjun Qin, Yingfei Li, Defu Zeng

Blood· April 2021

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IL-22-dependent dysbiosis and mononuclear phagocyte depletion contribute to steroid-resistant gut graft-versus-host disease in mice.
Qingxiao Song, Xiaoning Wang, Xiwei Wu, Tae Hyuk Kang, Hanjun Qin, Defu Zeng

Nat Commun· February 2021

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Tissue-resident PSGL1loCD4+ T cells promote B cell differentiation and chronic graft-versus-host disease-associated autoimmunity.
Xiaohui Kong, Deye Zeng, Xiwei Wu, Bixin Wang, Shijie Yang, Defu Zeng

J Clin Invest· January 2021

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Haploidentical mixed chimerism cures autoimmunity in established type 1 diabetic mice.
Yuqing Liu, Xiaoqi Wang, Yongping Zhu, Mingfeng Zhang, Ubaydah Nasri, Defu Zeng

J Clin Invest· December 2020

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Reversal of autoimmunity by mixed chimerism enables reactivation of β cells and transdifferentiation of α cells in diabetic NOD mice.
Shanshan Tang, Mingfeng Zhang, Samuel Zeng, Yaxun Huang, Melissa Qin, Defu Zeng

Proc Natl Acad Sci U S A· December 2020

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Mouse models usher in precision medicine.
Defu Zeng

Blood· June 2020

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Regulation of GVHD and GVL Activity via PD-L1 Interaction With PD-1 and CD80.
Kaniel Cassady, Paul J Martin, Defu Zeng

Front Immunol· October 2019

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Ethanol production from mixtures of sugarcane bagasse and Dioscorea composita extracted residue with high solid loading.
Guangying Ye, Defu Zeng, Shuaishuai Zhang, Meishan Fan, Hongdan Zhang

Bioresour Technol· June 2018

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