Publications by authors named "Denise Milot"

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Enhancing Studies of Pharmacodynamic Mechanisms via Measurements of Metabolic Flux: Fundamental Concepts and Guiding Principles for Using Stable Isotope Tracers.
Natalie A Daurio, Sheng-Ping Wang, Ying Chen, Haihong Zhou, David G McLaren, Denise Milot

J Pharmacol Exp Ther· October 2017

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SAR studies on the central phenyl ring of substituted biphenyl oxazolidinone-potent CETP inhibitors.
Zhijian Lu, Yi-Heng Chen, Joann B Napolitano, Gayle Taylor, Amjad Ali, Denise P Milot

Bioorg Med Chem Lett· January 2012

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Biphenyl-substituted oxazolidinones as cholesteryl ester transfer protein inhibitors: modifications of the oxazolidinone ring leading to the discovery of anacetrapib.
Cameron J Smith, Amjad Ali, Milton L Hammond, Hong Li, Zhijian Lu, Denise P Milot

J Med Chem· July 2011

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Discovery of substituted biphenyl oxazolidinone inhibitors of cholesteryl ester transfer protein.
Christopher F Thompson, Amjad Ali, Nazia Quraishi, Zhijian Lu, Milton L Hammond, Denise P Milot

ACS Med Chem Lett· June 2011

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2-(4-Carbonylphenyl)benzoxazole inhibitors of CETP: attenuation of hERG binding and improved HDLc-raising efficacy.
Ramzi F Sweis, Julianne A Hunt, Peter J Sinclair, Ying Chen, Suzanne S Eveland, Denise P Milot

Bioorg Med Chem Lett· May 2011

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2-(4-carbonylphenyl)benzoxazole inhibitors of CETP: scaffold design and advancement in HDLc-raising efficacy.
Ramzi F Sweis, Julianne A Hunt, Florida Kallashi, Milton L Hammond, Ying Chen, Denise P Milot

Bioorg Med Chem Lett· March 2011

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2-Arylbenzoxazoles as CETP inhibitors: raising HDL-C in cynoCETP transgenic mice.
Florida Kallashi, Dooseop Kim, Jennifer Kowalchick, You Jung Park, Julianne A Hunt, Denise P Milot

Bioorg Med Chem Lett· January 2011

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Design of a novel class of biphenyl CETP inhibitors.
Zhijian Lu, Joann B Napolitano, Ashleigh Theberge, Amjad Ali, Milton L Hammond, Denise P Milot

Bioorg Med Chem Lett· December 2010

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Biochemical characterization of cholesteryl ester transfer protein inhibitors.
Mollie Ranalletta, Kathleen K Bierilo, Ying Chen, Denise Milot, Qing Chen

J Lipid Res· September 2010

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2-Arylbenzoxazoles as CETP inhibitors: substitution and modification of the alpha-alkoxyamide moiety.
Julianne A Hunt, Silvia Gonzalez, Florida Kallashi, Milton L Hammond, James V Pivnichny, Denise P Milot

Bioorg Med Chem Lett· February 2010

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2-Arylbenzoxazoles as CETP inhibitors: Substitution of the benzoxazole moiety.
Cameron J Smith, Amjad Ali, Liya Chen, Milton L Hammond, Matt S Anderson, Denise P Milot

Bioorg Med Chem Lett· January 2010

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A high-precision fluorogenic cholesteryl ester transfer protein assay compatible with animal serum and 3456-well assay technology.
Suzanne S Eveland, Denise P Milot, Qiu Guo, Ying Chen, Sheryl A Hyland

Anal Biochem· September 2007

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Different roles of liver X receptor alpha and beta in lipid metabolism: effects of an alpha-selective and a dual agonist in mice deficient in each subtype.
Erik G Lund, Laurence B Peterson, Alan D Adams, My-Hanh N Lam, Charlotte A Burton, Denise P Milot

Biochem Pharmacol· February 2006

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A novel peroxisome proliferator-activated receptor alpha/gamma dual agonist demonstrates favorable effects on lipid homeostasis.
Qiu Guo, Soumya P Sahoo, Pei-Ran Wang, Denise P Milot, Marc C Ippolito

Endocrinology· April 2004

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Protein-disulfide isomerase is a component of an NBD-cholesterol monomerizing protein complex from hamster small intestine.
Tian-Quan Cai, Qiu Guo, Birming Wong, Denise Milot, Liwen Zhang

Biochim Biophys Acta· April 2002

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