Publications by authors named "Dooseop Kim"

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Discovery of a peripheral 5HT antagonist as a clinical candidate for metabolic dysfunction-associated steatohepatitis.
Haushabhau S Pagire, Suvarna H Pagire, Byung-Kwan Jeong, Won-Il Choi, Chang Joo Oh, Minhee Kim, Seong Soon Kim, Dooseop Kim, Hail Kim

Nat Commun· January 2024

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Design, Synthesis, and Biological Evaluation of New Peripheral 5HT Antagonists for Nonalcoholic Fatty Liver Disease.
Minhee Kim, Inseon Hwang, Haushabhau S Pagire, Suvarna H Pagire, Wonsuk Choi, Mi-Jin Kim, Dooseop Kim, Hail Kim

J Med Chem· April 2020

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NMR uncovers direct interaction between human NEDD4-1 and p34.
Pravesh Shrestha, Ji-Hye Yun, Yoon-Joo Ko, Kyu Jeong Yeon, Dooseop Kim

Biochem Biophys Res Commun· August 2017

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Discovery and optimization of adamantane carboxylic acid derivatives as potent diacylglycerol acyltransferase 1 inhibitors for the potential treatment of obesity and diabetes.
Suvarna H Pagire, Haushabhau S Pagire, Gwi Bin Lee, Seo-Jung Han, Hyun Jung Kwak, Ji Young Kim, Ki Young Kim, Dooseop Kim

Eur J Med Chem· August 2015

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2-Arylbenzoxazoles as CETP inhibitors: raising HDL-C in cynoCETP transgenic mice.
Florida Kallashi, Dooseop Kim, Jennifer Kowalchick, You Jung Park, Julianne A Hunt

Bioorg Med Chem Lett· January 2011

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Discovery of potent and selective dipeptidyl peptidase IV inhibitors derived from beta-aminoamides bearing subsituted triazolopiperazines.
Dooseop Kim, Jennifer E Kowalchick, Linda L Brockunier, Emma R Parmee, George J Eiermann

J Med Chem· February 2008

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Design, synthesis, and biological evaluation of triazolopiperazine-based beta-amino amides as potent, orally active dipeptidyl peptidase IV (DPP-4) inhibitors.
Jennifer E Kowalchick, Barbara Leiting, KellyAnn D Pryor, Frank Marsilio, Joseph K Wu, Dooseop Kim

Bioorg Med Chem Lett· November 2007

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Triazolopiperazine-amides as dipeptidyl peptidase IV inhibitors: close analogs of JANUVIA (sitagliptin phosphate).
Dooseop Kim, Jennifer E Kowalchick, Scott D Edmondson, Anthony Mastracchio, Jinyou Xu

Bioorg Med Chem Lett· June 2007

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Characterization of two cyclic metabolites of sitagliptin.
David Q Liu, Byron H Arison, Ralph A Stearns, Dooseop Kim, Stella H Vincent

Drug Metab Dispos· April 2007

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Dipeptidyl peptidase IV inhibition for the treatment of type 2 diabetes: potential importance of selectivity over dipeptidyl peptidases 8 and 9.
George R Lankas, Barbara Leiting, Ranabir Sinha Roy, George J Eiermann, Maria G Beconi, Dooseop Kim

Diabetes· October 2005

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Potent 1,3,4-trisubstituted pyrrolidine CCR5 receptor antagonists: effects of fused heterocycles on antiviral activity and pharmacokinetic properties.
Dooseop Kim, Liping Wang, Jeffrey J Hale, Christopher L Lynch, Richard J Budhu

Bioorg Med Chem Lett· April 2005

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(2R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine: a potent, orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.
Dooseop Kim, Liping Wang, Maria Beconi, George J Eiermann, Michael H Fisher

J Med Chem· January 2005

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