Publications by authors named "Derek A Persons"

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Lentiviral Transfer of γ-Globin with Fusion Gene NUP98-HOXA10HD Expands Hematopoietic Stem Cells and Ameliorates Murine β-Thalassemia.
Hui Fen Zhao, Allistair Abraham, Yoon-Sang Kim, Yong-Dong Wang, Tamara Pestina, Derek A Persons

Mol Ther· March 2017

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Increased Engraftment of Human Short Term Repopulating Hematopoietic Cells in NOD/SCID/IL2rγnull Mice by Lentiviral Expression of NUP98-HOXA10HD.
Allistair Abraham, Yoon-Sang Kim, Huifen Zhao, Keith Humphries, Derek A Persons

PLoS One· July 2016

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Data in support of transcriptional regulation and function of Fas-antisense long noncoding RNA during human erythropoiesis.
Olga Villamizar, Christopher B Chambers, Yin-Yuan Mo, Donald S Torry, Reese Hofstrand, Derek A Persons

Data Brief· June 2016

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Fas-antisense long noncoding RNA is differentially expressed during maturation of human erythrocytes and confers resistance to Fas-mediated cell death.
Olga Villamizar, Christopher B Chambers, Yin-Yuan Mo, Donald S Torry, Reese Hofstrand, Derek A Persons

Blood Cells Mol Dis· May 2016

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Long noncoding RNA Saf and splicing factor 45 increase soluble Fas and resistance to apoptosis.
Olga Villamizar, Christopher B Chambers, Janice M Riberdy, Derek A Persons, Andrew Wilber

Oncotarget· March 2016

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Amelioration of murine sickle cell disease by nonablative conditioning and γ-globin gene-corrected bone marrow cells.
Tamara I Pestina, Phillip W Hargrove, Huifen Zhao, Paul E Mead, Matthew P Smeltzer, Derek A Persons

Mol Ther Methods Clin Dev· December 2015

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Low-level GATA2 overexpression promotes myeloid progenitor self-renewal and blocks lymphoid differentiation in mice.
Satish K Nandakumar, Kyle Johnson, Stacy L Throm, Tamara I Pestina, Geoffrey Neale, Derek A Persons

Exp Hematol· July 2015

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High-titer foamy virus vector transduction and integration sites of human CD34(+) cell-derived SCID-repopulating cells.
Md Nasimuzzaman, Yoon-Sang Kim, Yong-Dong Wang, Derek A Persons

Mol Ther Methods Clin Dev· May 2015

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Potentially therapeutic levels of anti-sickling globin gene expression following lentivirus-mediated gene transfer in sickle cell disease bone marrow CD34+ cells.
Fabrizia Urbinati, Phillip W Hargrove, Sabine Geiger, Zulema Romero, Jennifer Wherley, Derek A Persons

Exp Hematol· May 2015

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Nfix is a novel regulator of murine hematopoietic stem and progenitor cell survival.
Per Holmfeldt, Jennifer Pardieck, Anjelica C Saulsberry, Satish Kumar Nandakumar, David Finkelstein, Derek A Persons

Blood· October 2013

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Development of gene therapy for thalassemia.
Arthur W Nienhuis, Derek A Persons

Cold Spring Harb Perspect Med· November 2012

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High-efficiency transduction of rhesus hematopoietic repopulating cells by a modified HIV1-based lentiviral vector.
Naoya Uchida, Phillip W Hargrove, Coen J Lap, Molly E Evans, Oswald Phang, Derek A Persons

Mol Ther· October 2012

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Cell Membrane-associated heparan sulfate is a receptor for prototype foamy virus in human, monkey, and rodent cells.
Md Nasimuzzaman, Derek A Persons

Mol Ther· June 2012

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Hydroxyurea therapy of a murine model of sickle cell anemia inhibits the progression of pneumococcal disease by down-modulating E-selectin.
Jeffrey D Lebensburger, Thad Howard, Yunming Hu, Tamara I Pestina, Geli Gao, Derek A Persons

Blood· February 2012

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Therapeutic in vivo selection of thymic-derived natural T regulatory cells following non-myeloablative hematopoietic stem cell transplant for IPEX.
Kimberly A Kasow, Vanessa M Morales-Tirado, David Wichlan, Sheila A Shurtleff, Allistair Abraham, Derek A Persons

Clin Immunol· November 2011

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Gene therapy for canine leukocyte adhesion deficiency with lentiviral vectors using the murine stem cell virus and human phosphoglycerate kinase promoters.
Michael J Hunter, Huifen Zhao, Laura M Tuschong, Thomas R Bauer, Tanya H Burkholder, Derek A Persons

Hum Gene Ther· June 2011

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Transcriptional regulation of fetal to adult hemoglobin switching: new therapeutic opportunities.
Andrew Wilber, Arthur W Nienhuis, Derek A Persons

Blood· April 2011

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Therapeutic levels of fetal hemoglobin in erythroid progeny of β-thalassemic CD34+ cells after lentiviral vector-mediated gene transfer.
Andrew Wilber, Phillip W Hargrove, Yoon-Sang Kim, Janice M Riberdy, Vijay G Sankaran, Derek A Persons

Blood· March 2011

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Solving the problem of γ-retroviral vectors containing long terminal repeats.
Derek A Persons, Christopher Baum

Mol Ther· February 2011

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Analysis of alpha hemoglobin stabilizing protein overexpression in murine β-thalassemia.
Md Nasimuzzaman, Eugene Khandros, Xiaomei Wang, Yi Kong, Huifen Zhao, Derek A Persons

Am J Hematol· October 2010

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Hydroxyurea therapy requires HbF induction for clinical benefit in a sickle cell mouse model.
Jeffrey D Lebensburger, Tamara I Pestina, Russell E Ware, Kelli L Boyd, Derek A Persons

Haematologica· September 2010

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Gene therapy: Targeting β-thalassaemia.
Derek A Persons

Nature· September 2010

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The challenge of obtaining therapeutic levels of genetically modified hematopoietic stem cells in beta-thalassemia patients.
Derek A Persons

Ann N Y Acad Sci· August 2010

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Transduction of human primitive repopulating hematopoietic cells with lentiviral vectors pseudotyped with various envelope proteins.
Yoon-Sang Kim, Matthew M Wielgosz, Phillip Hargrove, Steven Kepes, John Gray, Derek A Persons

Mol Ther· July 2010

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Lentiviral vector gene therapy: effective and safe?
Derek A Persons

Mol Ther· May 2010

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