Publications by authors named "Derek Nolan"

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The -Derived Ketoacids, Indole Pyruvate and Hydroxyphenylpyruvate, Induce HO-1 Expression and Suppress Inflammatory Responses in Human Dendritic Cells.
Hannah K Fitzgerald, Sinead A O'Rourke, Eva Desmond, Nuno G B Neto, Michael G Monaghan, Derek P Nolan

Antioxidants (Basel)· January 2022

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The Trypanosome-Derived Metabolite Indole-3-Pyruvate Inhibits Prostaglandin Production in Macrophages by Targeting COX2.
Ciana Diskin, Sarah E Corcoran, Victoria J Tyrrell, Anne F McGettrick, Zbigniew Zaslona, Derek P Nolan

J Immunol· November 2021

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Genetic and immunological basis of human African trypanosomiasis.
Etienne Pays, Derek P Nolan

Curr Opin Immunol· October 2021

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Secreted Aromatic Ketoacids Activate the Nrf2/HO-1 Pathway and Suppress Pro-inflammatory Responses in Primary Murine Glia and Macrophages.
Nicole K Campbell, David G Williams, Hannah K Fitzgerald, Paul J Barry, Clare C Cunningham, Derek P Nolan

Front Immunol· October 2020

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The KIFC1 Kinesin Ensures the Fast Antibody Clearance Required for Parasite Infectivity.
Laurence Lecordier, Sophie Uzureau, Gilles Vanwalleghem, Magali Deleu, Jean-Marc Crowet, Derek P Nolan

iScience· September 2020

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Queuine Micronutrient Deficiency Promotes Warburg Metabolism and Reversal of the Mitochondrial ATP Synthase in Hela Cells.
Patti Hayes, Claire Fergus, Magda Ghanim, Cansu Cirzi, Lyubomyr Burtnyak, Derek P Nolan

Nutrients· March 2020

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Metabolic reprogramming during the life cycle.
Terry K Smith, Frédéric Bringaud, Derek P Nolan, Luisa M Figueiredo

F1000Res· May 2017

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Trypanosoma brucei metabolite indolepyruvate decreases HIF-1α and glycolysis in macrophages as a mechanism of innate immune evasion.
Anne F McGettrick, Sarah E Corcoran, Paul J G Barry, Jennifer McFarland, Cécile Crès, Derek P Nolan

Proc Natl Acad Sci U S A· November 2016

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Coupling of lysosomal and mitochondrial membrane permeabilization in trypanolysis by APOL1.
Gilles Vanwalleghem, Frédéric Fontaine, Laurence Lecordier, Patricia Tebabi, Kristoffer Klewe, Derek P Nolan

Nat Commun· August 2015

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Detailed Biological Profiling of a Photoactivated and Apoptosis Inducing pdppz Ruthenium(II) Polypyridyl Complex in Cancer Cells.
Suzanne M Cloonan, Robert B P Elmes, MariaLuisa Erby, Sandra A Bright, Fergus E Poynton, Derek E Nolan

J Med Chem· June 2015

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TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei.
Sanu Shameer, Flora J Logan-Klumpler, Florence Vinson, Ludovic Cottret, Benjamin Merlet, Derek P Nolan

Nucleic Acids Res· January 2015

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Identification of Trypanosoma brucei components involved in trypanolysis by normal human serum.
Laurence Lecordier, Pierrick Uzureau, Patricia Tebabi, David Pérez-Morga, Derek Nolan

Mol Microbiol· November 2014

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Preparation, anti-trypanosomal activity and localisation of a series of dipeptide-based vinyl sulfones.
William Doherty, Jinju James, Paul Evans, Laura Martin, Nikoletta Adler, Derek Nolan

Org Biomol Chem· October 2014

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Inhibition of late-stage autophagy synergistically enhances pyrrolo-1,5-benzoxazepine-6-induced apoptotic cell death in human colon cancer cells.
Lisa M Greene, Derek P Nolan, Daniel Regan-Komito, Giuseppe Campiani, D Clive Williams

Int J Oncol· September 2013

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Vinyl sulfone-based peptidomimetics as anti-trypanosomal agents: design, synthesis, biological and computational evaluation.
Elizabeth Dunny, William Doherty, Paul Evans, J Paul G Malthouse, Derek Nolan

J Med Chem· September 2013

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Mechanism of Trypanosoma brucei gambiense resistance to human serum.
Pierrick Uzureau, Sophie Uzureau, Laurence Lecordier, Frédéric Fontaine, Patricia Tebabi, Derek P Nolan

Nature· September 2013

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Identification and characterization of a stage specific membrane protein involved in flagellar attachment in Trypanosoma brucei.
Katherine Woods, Noirin Nic a'Bhaird, Clodagh Dooley, David Perez-Morga, Derek P Nolan

PLoS One· June 2013

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The vascular targeting agent Combretastatin-A4 directly induces autophagy in adenocarcinoma-derived colon cancer cells.
Lisa M Greene, Niamh M O'Boyle, Derek P Nolan, Mary J Meegan, Daniela M Zisterer

Biochem Pharmacol· September 2012

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Identification and characterization of an unusual class I myosin involved in vesicle traffic in Trypanosoma brucei.
Diana Spitznagel, John F O'Rourke, Neal Leddy, Orla Hanrahan, Derek P Nolan

PLoS One· August 2010

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Alanine aminotransferase of Trypanosoma brucei--a key role in proline metabolism in procyclic life forms.
Diana Spitznagel, Charles Ebikeme, Marc Biran, Nóirín Nic a' Bháird, Frédéric Bringaud, Derek P Nolan

FEBS J· December 2009

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Glucose-induced remodeling of intermediary and energy metabolism in procyclic Trypanosoma brucei.
Virginie Coustou, Marc Biran, Marc Breton, Fabien Guegan, Loïc Rivière, Derek Nolan

J Biol Chem· June 2008

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Images of mitochondrial UCP 1 in mouse thymocytes using confocal microscopy.
Alison E Adams, Orla Hanrahan, Derek N Nolan, H Paul Voorheis, Padraic Fallon

Biochim Biophys Acta· February 2008

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Loss of actin does not affect export of newly synthesized proteins to the surface of Trypanosoma brucei.
Derek P Nolan, Jose A Garcia-Salcedo

Mol Biochem Parasitol· February 2008

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Anti-Trypanosoma brucei activity in Cape buffalo serum during the cryptic phase of parasitemia is mediated by antibodies.
Patrick Guirnalda, Noel B Murphy, Derek Nolan, Samuel J Black

Int J Parasitol· October 2007

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The trypanolytic factor of human serum.
Etienne Pays, Benoit Vanhollebeke, Luc Vanhamme, Françoise Paturiaux-Hanocq, Derek P Nolan

Nat Rev Microbiol· June 2006

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