Publications by authors named "Dev Trivedi"

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Design of novel melanocortin receptor ligands: multiple receptors, complex pharmacology, the challenge.
Victor J Hruby, Minying Cai, James Cain, Joel Nyberg, Dev Trivedi

Eur J Pharmacol· June 2011

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Cyclic lactam hybrid α-MSH/Agouti-related protein (AGRP) analogues with nanomolar range binding affinities at the human melanocortin receptors.
Alexander V Mayorov, Minying Cai, Erin S Palmer, Dustin K Tanaka, James P Cain, Dev Trivedi

Bioorg Med Chem Lett· May 2011

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Solid-phase peptide head-to-side chain cyclodimerization: discovery of C(2)-symmetric cyclic lactam hybrid α-melanocyte-stimulating hormone (MSH)/agouti-signaling protein (ASIP) analogues with potent activities at the human melanocortin receptors.
Alexander V Mayorov, Minying Cai, Erin S Palmer, Zhihua Liu, James P Cain, Dev Trivedi

Peptides· October 2010

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Peptide and non-peptide mimetics utilize different pathways for signal transduction.
Victor J Hruby, Minying Cai, Matt Dedek, Hongchang Qu, Erin Palmer, Dev Trivedi

Adv Exp Med Biol· June 2009

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Substitution of arginine with proline and proline derivatives in melanocyte-stimulating hormones leads to selectivity for human melanocortin 4 receptor.
Hongchang Qu, Minying Cai, Alexander V Mayorov, Paolo Grieco, Morgan Zingsheim, Dev Trivedi

J Med Chem· June 2009

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Opioid and melanocortin receptors: do they have overlapping pharmacophores?
Yeon Sun Lee, Richard S Agnes, James P Cain, Vinod Kulkarni, Minying Cai, Dev Trivedi

Biopolymers· July 2008

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Design and microwave-assisted synthesis of novel macrocyclic peptides active at melanocortin receptors: discovery of potent and selective hMC5R receptor antagonists.
Paolo Grieco, Minying Cai, Lu Liu, Alexander Mayorov, Kevin Chandler, Dev Trivedi

J Med Chem· May 2008

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Structure-activity relationships of cyclic lactam analogues of alpha-melanocyte-stimulating hormone (alpha-MSH) targeting the human melanocortin-3 receptor.
Alexander V Mayorov, Minying Cai, Erin S Palmer, Matthew M Dedek, James P Cain, Dev Trivedi

J Med Chem· January 2008

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Further structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5.
Paolo Grieco, Minying Cai, Guoxia Han, Dev Trivedi, Pietro Campiglia

Peptides· June 2007

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Design, synthesis, and biological evaluation of new cyclic melanotropin peptide analogues selective for the human melanocortin-4 receptor.
Jinfa Ying, Xuyuan Gu, Minying Cai, Matthew Dedek, Josef Vagner, Dev B Trivedi

J Med Chem· November 2006

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Design, synthesis, and biological evaluation of a new class of small molecule peptide mimetics targeting the melanocortin receptors.
James P Cain, Alexander V Mayorov, Minying Cai, Hui Wang, Bahar Tan, Dev Trivedi

Bioorg Med Chem Lett· October 2006

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Cell signaling and trafficking of human melanocortin receptors in real time using two-photon fluorescence and confocal laser microscopy: differentiation of agonists and antagonists.
Minying Cai, Eva V Varga, Magda Stankova, Alexander Mayorov, Joseph W Perry, Dev Trivedi

Chem Biol Drug Des· October 2006

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Effects of macrocycle size and rigidity on melanocortin receptor-1 and -5 selectivity in cyclic lactam alpha-melanocyte-stimulating hormone analogs.
Alexander V Mayorov, So-Yeop Han, Minying Cai, Matthew R Hammer, Dev Trivedi

Chem Biol Drug Des· May 2006

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Development of cyclic gamma-MSH analogues with selective hMC3R agonist and hMC3R/hMC5R antagonist activities.
Alexander V Mayorov, Minying Cai, Kevin B Chandler, Ravil R Petrov, April R Van Scoy, Dev Trivedi

J Med Chem· March 2006

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Structure-activity studies of new melanocortin peptides containing an aromatic amino acid at the N-terminal position.
Paolo Grieco, Minying Cai, Alexander V Mayorov, Dev Trivedi, Victor J Hruby

Peptides· February 2006

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Design of novel melanotropin agonists and antagonists with high potency and selectivity for human melanocortin receptors.
Minying Cai, Alexander V Mayorov, Jinfa Ying, Magda Stankova, Dev Trivedi

Peptides· August 2005

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Novel 3D pharmacophore of alpha-MSH/gamma-MSH hybrids leads to selective human MC1R and MC3R analogues.
Minying Cai, Alexander V Mayorov, Christopher Cabello, Magda Stankova, Dev Trivedi

J Med Chem· March 2005

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Real time differentiation of G-protein coupled receptor (GPCR) agonist and antagonist by two photon fluorescence laser microscopy.
Minying Cai, Magda Stankova, Stephanie J K Pond, Alexander V Mayorov, Joseph W Perry, Dev Trivedi

J Am Chem Soc· June 2004

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Solution structures of cyclic melanocortin agonists and antagonists by NMR.
Jinfa Ying, Katalin E Kövér, Xuyuan Gu, Guoxia Han, Dev B Trivedi

Biopolymers· April 2004

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Structure-activity relationships of gamma-MSH analogues at the human melanocortin MC3, MC4, and MC5 receptors. Discovery of highly selective hMC3R, hMC4R, and hMC5R analogues.
Preeti Balse-Srinivasan, Paolo Grieco, Minying Cai, Dev Trivedi, Victor J Hruby

J Med Chem· November 2003

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Structure-activity relationships of novel cyclic alpha-MSH/beta-MSH hybrid analogues that lead to potent and selective ligands for the human MC3R and human MC5R.
Preeti Balse-Srinivasan, Paolo Grieco, Minying Cai, Dev Trivedi, Victor J Hruby

J Med Chem· August 2003

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Exploring the stereostructural requirements of peptide ligands for the melanocortin receptors.
Victor J Hruby, Minying Cai, Paolo Grieco, Guoxia Han, Malcolm Kavarana, Dev Trivedi

Ann N Y Acad Sci· June 2003

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Novel cyclic templates of alpha-MSH give highly selective and potent antagonists/agonists for human melanocortin-3/4 receptors.
Malcolm J Kavarana, Dev Trivedi, Minying Cai, Jinfa Ying, Matthew Hammer

J Med Chem· June 2002

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