Publications by authors named "Dhavalkumar D Patel"

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Neonatal Fc receptor in human immunity: Function and role in therapeutic intervention.
Dhavalkumar D Patel, James B Bussel

J Allergy Clin Immunol· September 2020

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TNF-α-induced protein 3 (A20): The immunological rheostat.
Asher Maroof, Dhavalkumar D Patel

J Allergy Clin Immunol· August 2018

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Effective "activated PI3Kδ syndrome"-targeted therapy with the PI3Kδ inhibitor leniolisib.
V Koneti Rao, Sharon Webster, Virgil A S H Dalm, Anna Šedivá, P Martin van Hagen, Dhavalkumar D Patel

Blood· November 2017

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Phase 2 to phase 3 clinical trial transitions: Reasons for success and failure in immunologic diseases.
Dhavalkumar D Patel, Christian Antoni, Steven J Freedman, Marc C Levesque, John S Sundy

J Allergy Clin Immunol· September 2017

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β-Defensin 2 is a responsive biomarker of IL-17A-driven skin pathology in patients with psoriasis.
Frank Kolbinger, Christian Loesche, Marie-Anne Valentin, Xiaoyu Jiang, Yi Cheng, Dhavalkumar D Patel

J Allergy Clin Immunol· March 2017

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Retinoic-acid-orphan-receptor-C inhibition suppresses Th17 cells and induces thymic aberrations.
Christine Guntermann, Alessandro Piaia, Marie-Laure Hamel, Diethilde Theil, Tina Rubic-Schneider, Dhavalkumar D Patel

JCI Insight· March 2017

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Th17 Cell Pathway in Human Immunity: Lessons from Genetics and Therapeutic Interventions.
Dhavalkumar D Patel, Vijay K Kuchroo

Immunity· December 2015

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Deficiency of MALT1 paracaspase activity results in unbalanced regulatory and effector T and B cell responses leading to multiorgan inflammation.
Frédéric Bornancin, Florian Renner, Ratiba Touil, Heiko Sic, Yeter Kolb, Dhavalkumar D Patel

J Immunol· April 2015

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Preclinical target validation using patient-derived cells.
Aled M Edwards, Cheryl H Arrowsmith, Chas Bountra, Mark E Bunnage, Marc Feldmann, Dhavalkumar D Patel

Nat Rev Drug Discov· March 2015

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Effect of IL-17A blockade with secukinumab in autoimmune diseases.
Dhavalkumar D Patel, David M Lee, Frank Kolbinger, Christian Antoni

Ann Rheum Dis· April 2013

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Decreased Th17 and antigen-specific humoral responses in CX₃ CR1-deficient mice in the collagen-induced arthritis model.
Teresa K Tarrant, Peng Liu, Rishi R Rampersad, Denise Esserman, Lisa R Rothlein, Dhavalkumar D Patel

Arthritis Rheum· May 2012

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Enhanced Th17-cell responses render CCR2-deficient mice more susceptible for autoimmune arthritis.
Rishi R Rampersad, Teresa K Tarrant, Christopher T Vallanat, Tatiana Quintero-Matthews, Michael F Weeks, Dhavalkumar D Patel

PLoS One· February 2012

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Th17 cells, not IL-17+ γδ T cells, drive arthritic bone destruction in mice and humans.
Bernadette Pöllinger, Tobias Junt, Barbara Metzler, Ulrich A Walker, Alan Tyndall, Dhavalkumar D Patel

J Immunol· February 2011

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Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis.
Wolfgang Hueber, Dhavalkumar D Patel, Thaddeus Dryja, Andrew M Wright, Irina Koroleva

Sci Transl Med· October 2010

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Dual targeting of CCR2 and CX3CR1 in an arterial injury model of vascular inflammation.
Maya R Jerath, Peng Liu, Mary Struthers, Julie A Demartino, Roche Peng, Dhavalkumar D Patel

Thromb J· September 2010

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Granulocyte chemotaxis and disease expression are differentially regulated by GRK subtype in an acute inflammatory arthritis model (K/BxN).
Teresa K Tarrant, Rishi R Rampersad, Denise Esserman, Lisa R Rothlein, Peng Liu, Dhavalkumar D Patel

Clin Immunol· October 2008

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CX3CR1 deficiency impairs dendritic cell accumulation in arterial intima and reduces atherosclerotic burden.
Peng Liu, Yen-Rei A Yu, Jessica A Spencer, Ashley E Johnson, Christopher T Vallanat, Dhavalkumar D Patel

Arterioscler Thromb Vasc Biol· February 2008

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Ozone enhancement of lower airway allergic inflammation is prevented by gamma-tocopherol.
James G Wagner, Qing Jiang, Jack R Harkema, Beate Illek, Dhavalkumar D Patel

Free Radic Biol Med· October 2007

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Defective antitumor responses in CX3CR1-deficient mice.
Yen-Rei A Yu, Alan M Fong, Christophe Combadiere, Ji-Liang Gao, Philip M Murphy, Dhavalkumar D Patel

Int J Cancer· July 2007

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Rapamycin is efficacious against primary effusion lymphoma (PEL) cell lines in vivo by inhibiting autocrine signaling.
Sang-Hoon Sin, Debasmita Roy, Ling Wang, Michelle R Staudt, Farnaz D Fakhari, Dhavalkumar D Patel

Blood· March 2007

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Randomized controlled trials of autologous hematopoietic stem cell transplantation for autoimmune diseases: the evolution from myeloablative to lymphoablative transplant regimens.
Richard K Burt, Alberto Marmont, Yu Oyama, Shimon Slavin, Renate Arnold, Dhavalkumar D Patel

Arthritis Rheum· December 2006

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Elevated serum levels of interferon-regulated chemokines are biomarkers for active human systemic lupus erythematosus.
Jason W Bauer, Emily C Baechler, Michelle Petri, Franak M Batliwalla, Dianna Crawford, Dhavalkumar D Patel

PLoS Med· December 2006

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Cetuximab-associated infusion reactions: pathology and management.
Dhavalkumar D Patel, Richard M Goldberg

Oncology (Williston Park)· October 2006

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CX3CR1 deficiency confers protection from intimal hyperplasia after arterial injury.
Peng Liu, Sarita Patil, Mauricio Rojas, Alan M Fong, Susan S Smyth, Dhavalkumar D Patel

Arterioscler Thromb Vasc Biol· September 2006

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Use of intravenous immunoglobulin in human disease: a review of evidence by members of the Primary Immunodeficiency Committee of the American Academy of Allergy, Asthma and Immunology.
Jordan S Orange, Elham M Hossny, Catherine R Weiler, Mark Ballow, Melvin Berger, Dhavalkumar D Patel

J Allergy Clin Immunol· April 2006

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