Publications by authors named "Dion Brocks"

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Double Peaking Phenomena in Pharmacokinetic Disposition Revisited.
Malaz Yousef, Dion R Brocks, Raimar Löbenberg, Neal M Davies

Clin Pharmacokinet· October 2025

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The stereoselective pharmacokinetics of bupivacaine after racemate, and the effects of high-fat diet and sex in Sprague-Dawley rats.
Shamima Parvin, Neal M Davies, John R Ussher, Dion R Brocks

J Pharm Pharmacol· October 2025

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Development of a succinyl CoA:3-ketoacid CoA transferase inhibitor selective for peripheral tissues that improves glycemia in obesity.
Seyed Amirhossein Tabatabaei Dakhili, Kunyan Yang, Hamdah Al Nebaihi, Amanda A Greenwell, Melinda Wuest, Dion R Brocks

iScience· May 2025

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The application of Bayesian forecasting to explore the effects of sex and high-fat diet on the pharmacokinetics of ropivacaine in the rat.
Shamima Parvin, Hamdah M Al Nebaihi, John R Ussher, Dion R Brocks

J Pharmacol Toxicol Methods· March 2025

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Quantification of Epoxyeicosatrienoic acids Enantiomers: The development of reliable and practical liquid chromatography mass Spectrometry assay.
Fadumo A Isse, Sara Helal, Ahmed A El-Sherbeni, Dion R Brocks, Ayman O S El-Kadi

J Chromatogr B Analyt Technol Biomed Life Sci· October 2024

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Evaluation of the pharmacokinetics, chylomicron inhibition, and toxicity of colchicine in rats given low doses.
Hamdah M Al Nebaihi, Neal M Davies, Dion R Brocks

Eur J Pharm Biopharm· September 2024

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16R-HETE and 16S-HETE alter human cytochrome P450 1B1 enzyme activity probably through an allosteric mechanism.
Rahmat Hidayat, Sherif M Shoieb, Farag E S Mosa, Khaled Barakat, Dion R Brocks

Mol Cell Biochem· June 2024

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Exploring various measures of the area under the curve for the assessment of dose-proportionality and estimation of bioavailability.
Dion R Brocks, Elisabeth A Minthorn, Brian E Davies

J Pharm Pharmacol· March 2024

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Pharmacokinetics of cycloheximide in rats and evaluation of its effect as a blocker of intestinal lymph formation.
Hamdah M Al Nebaihi, Neal M Davies, Dion R Brocks

Eur J Pharm Biopharm· December 2023

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Use of a common spreadsheet program to demonstrate the ability of Bayesian forecasting to estimate the pharmacokinetic parameters of antibiotics.
Dion R Brocks, Meng Wang

J Pharm Pharmacol· October 2023

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The enantioselective separation and quantitation of the hydroxy-metabolites of arachidonic acid by liquid chromatography - tandem mass spectrometry.
Fadumo Ahmed Isse, Ahmad H Alammari, Ahmed A El-Sherbeni, Dion R Brocks, Ayman O S El-Kadi

Prostaglandins Other Lipid Mediat· April 2023

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Piecing together human adult comparative pharmacokinetic trials and rodent studies: What happens to drug clearance in obesity?
Dion Brocks, Hamdah Al Nebaihi, Shamima Parvin, Amel Hamza

J Pharm Pharm Sci· March 2022

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Analysis of cycloheximide in rat specimens using liquid chromatography with tandem massspectrometry detection.
Hamdah M Al Nebaihi, Tyson S Le, Neal M Davies, Dion R Brocks

J Chromatogr B Analyt Technol Biomed Life Sci· February 2022

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Does a sudden shift of testing format from closed-book to open-book change the characteristics of test scores on summative final exams?
M Ken Cor, Dion R Brocks

Curr Pharm Teach Learn· September 2021

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Online interviews for the selection of applicants for admission into an entry to practice program in pharmacy: Relationship to performance and student perspectives.
Ken Cor, Ravina Snghera, Dion R Brocks

Curr Pharm Teach Learn· June 2021

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Bayesian estimation of pharmacokinetic parameters: an important component to include in the teaching of clinical pharmacokinetics and therapeutic drug monitoring.
Dion R Brocks, Dalia A Hamdy

Res Pharm Sci· December 2020

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Dronedarone: the effect of diet-induced obesity on its metabolism and experimental hyperlipidemia on its metabolism and tissue distribution in the rat.
Yousef A Bin Jardan, Ali Abdussalam, Ayman O S El-Kadi, Dion R Brocks

Can J Physiol Pharmacol· March 2020

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Dietary-Induced Obesity, Hepatic Cytochrome P450, and Lidocaine Metabolism: Comparative Effects of High-Fat Diets in Mice and Rats and Reversibility of Effects With Normalization of Diet.
Hamdah M Al Nebaihi, Rami Al Batran, John R Ussher, Zaid H Maayah, Ayman O S El-Kadi, Dion R Brocks

J Pharm Sci· February 2020

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Positron Emission Tomography (PET) and Pharmacokinetics: Classical Blood Sampling Versus Image-Derived Analysis of [18F]FAZA and [18F]FDG in a Murine Tumor Bearing Model.
Hans-Soenke Jans, Xiao-Hong Yang, Dion R Brocks, Piyush Kumar, Melinda Wuest

J Pharm Pharm Sci· October 2019

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Lymphatic Drug Absorption via the Enterocytes: Pharmacokinetic Simulation, Modeling, and Considerations for Optimal Drug Development.
Dion R Brocks, Neal M Davies

J Pharm Pharm Sci· October 2019

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Rectus sheath single-injection blocks: a study to quantify local anaesthetic absorption using serial ultrasound measurements and lidocaine serum concentrations.
Matthew Primrose, Hamdah Al Nebaihi, Dion R Brocks, Sandy Widder, Adrian Fairey

J Pharm Pharmacol· August 2019

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Dietary-Induced Obesity and Changes in the Biodistribution and Metabolism of Amiodarone in the Rat.
Ali Abdussalam, Marwa Al-Agili, Hamdah M Al Nebaihi, Patrick R Mayo, Raniah Q Gabr, Dion R Brocks

J Pharm Sci· November 2018

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Examining the relationship between prerequisite grades and types of academic performance in pharmacy school.
M Ken Cor, Dion R Brocks

Curr Pharm Teach Learn· June 2018

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Identification and Characterization of Novel Receptor-Interacting Serine/Threonine-Protein Kinase 2 Inhibitors Using Structural Similarity Analysis.
Mohamed Salla, Rodrigo Aguayo-Ortiz, Gaddafi I Danmaliki, Alaa Zare, Ahmed Said, Dion Brocks

J Pharmacol Exp Ther· May 2018

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A High-Performance Liquid Chromatography Assay Method for the Determination of Lidocaine in Human Serum.
Hamdah M Al Nebaihi, Matthew Primrose, James S Green, Dion R Brocks

Pharmaceutics· November 2017

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