Publications by authors named "Diptesh Sil"

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Bioactive polymers as stimulus-responsive anti-metastatic combination agents to treat pancreatic cancer.
Sudipta Panja, Ekta Kapoor, Kasturi Siddhanta, Chinmay M Jogdeo, Diptesh Sil

Biomaterials· September 2025

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Antimalarial Dibenzannulated Medium-Ring Keto Lactams.
Rongguo Ren, Xiaofang Wang, Derek A Leas, Christian Scheurer, Sarah Hoevel, Diptesh Sil

ACS Infect Dis· October 2023

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Effect of tocopherol conjugation on polycation-mediated siRNA delivery to orthotopic pancreatic tumors.
Siyuan Tang, Ekta Kapoor, Ling Ding, Ao Yu, Weimin Tang, Diptesh Sil

Biomater Adv· February 2023

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Oral Delivery of Nucleic Acid Therapies for Local and Systemic Action.
Neha Kumari, Kasturi Siddhanta, Sudipta Panja, Vineet Joshi, Chinmay Jogdeo, Diptesh Sil

Pharm Res· January 2023

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Hyaluronate-coated perfluoroalkyl polyamine prodrugs as bioactive siRNA delivery systems for the treatment of peritoneal cancers.
Ao Yu, Siyuan Tang, Ling Ding, Jackson Foley, Weimin Tang, Diptesh Sil

Biomater Adv· May 2022

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Self-Assembled Alkylated Polyamine Analogs as Supramolecular Anticancer Agents.
Diptesh Sil, Sudipta Panja, Chinmay M Jogdeo, Raj Kumar, Ao Yu

Molecules· April 2022

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Perfluorocarbon Nanoemulsions Enhance Therapeutic siRNA Delivery in the Treatment of Pulmonary Fibrosis.
Ling Ding, Siyuan Tang, Weimin Tang, Deanna D Mosley, Ao Yu, Diptesh Sil

Adv Sci (Weinh)· March 2022

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Dually Active Polycation/miRNA Nanoparticles for the Treatment of Fibrosis in Alcohol-Associated Liver Disease.
Chuhan Zhang, Yu Hang, Weimin Tang, Diptesh Sil, Heather C Jensen-Smith

Pharmaceutics· March 2022

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Intraperitoneal siRNA Nanoparticles for Augmentation of Gemcitabine Efficacy in the Treatment of Pancreatic Cancer.
Siyuan Tang, Yu Hang, Ling Ding, Weimin Tang, Ao Yu, Diptesh Sil

Mol Pharm· December 2021

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Polycation fluorination improves intraperitoneal siRNA delivery in metastatic pancreatic cancer.
Yu Hang, Siyuan Tang, Weimin Tang, David Větvička, Chuhan Zhang, Diptesh Sil

J Control Release· May 2021

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Structure-Based Design of Human TLR8-Specific Agonists with Augmented Potency and Adjuvanticity.
Mallesh Beesu, Giuseppe Caruso, Alex C D Salyer, Karishma K Khetani, Diptesh Sil

J Med Chem· October 2015

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Determinants of activity at human Toll-like receptors 7 and 8: quantitative structure-activity relationship (QSAR) of diverse heterocyclic scaffolds.
Euna Yoo, Deepak B Salunke, Diptesh Sil, Xiaoqiang Guo, Alex C D Salyer

J Med Chem· October 2014

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Structure-based design of novel human Toll-like receptor 8 agonists.
Hari Prasad Kokatla, Diptesh Sil, Hiromi Tanji, Umeharu Ohto, Subbalakshmi S Malladi

ChemMedChem· April 2014

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Biophysical mechanisms of the neutralization of endotoxins by lipopolyamines.
Diptesh Sil, Lena Heinbockel, Yani Kaconis, Manfred Rössle, Patrick Garidel

Open Biochem J· October 2013

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Exquisite selectivity for human toll-like receptor 8 in substituted furo[2,3-c]quinolines.
Hari Prasad Kokatla, Diptesh Sil, Subbalakshmi S Malladi, Rajalakshmi Balakrishna, Alec R Hermanson

J Med Chem· September 2013

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Toll-like receptor-8 agonistic activities in C2, C4, and C8 modified thiazolo[4,5-c]quinolines.
Hari Prasad Kokatla, Euna Yoo, Deepak B Salunke, Diptesh Sil, Cameron F Ng

Org Biomol Chem· February 2013

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Imbuing aqueous solubility to amphotericin B and nystatin with a vitamin.
Timothy P Day, Diptesh Sil, Nikunj M Shukla, Asokan Anbanandam, Victor W Day

Mol Pharm· February 2011

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Development of small-molecule endotoxin sequestering agents.
Sunil A David, Diptesh Sil

Subcell Biochem· September 2010

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Synthesis of a highly water-soluble derivative of amphotericin B with attenuated proinflammatory activity.
Samusi A Adediran, Timothy P Day, Diptesh Sil, Matthew R Kimbrell, Hemamali J Warshakoon

Mol Pharm· December 2009

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Potential adjuvantic properties of innate immune stimuli.
Hemamali J Warshakoon, Jennifer D Hood, Matthew R Kimbrell, Subbalakshmi Malladi, Wen Yan Wu, Diptesh Sil

Hum Vaccin· June 2009

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Controlling plasma protein binding: structural correlates of interactions of hydrophobic polyamine endotoxin sequestrants with human serum albumin.
Thuan B Nguyen, E V K Suresh Kumar, Diptesh Sil, Stewart J Wood, Kelly A Miller

Mol Pharm· June 2009

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Structure-activity relationships of lipopolysaccharide sequestration in N-alkylpolyamines.
Anurupa Shrestha, Diptesh Sil, Subbalakshmi S Malladi, Hemamali J Warshakoon, Sunil A David

Bioorg Med Chem Lett· May 2009

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Structure-activity relationships of lipopolysaccharide sequestration in guanylhydrazone-bearing lipopolyamines.
Wenyan Wu, Diptesh Sil, Michal L Szostak, Subbalakshmi S Malladi, Hemamali J Warshakoon

Bioorg Med Chem· January 2009

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Pharmacokinetics of DS-96, an alkylpolyamine lipopolysaccharide sequestrant, in rodents.
Anurupa Shrestha, Rongti Li, Diptesh Sil, Neha N Pardeshi, Nancy Schwarting

J Pharm Sci· December 2008

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Bound to shock: protection from lethal endotoxemic shock by a novel, nontoxic, alkylpolyamine lipopolysaccharide sequestrant.
Diptesh Sil, Anurupa Shrestha, Matthew R Kimbrell, Thuan B Nguyen, Ashok K Adisechan

Antimicrob Agents Chemother· August 2007

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