Publications by authors named "Dirk M Zajonc"

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Agonism of 4-1BB for immune therapy: a perspective on possibilities and complications.
Shahram Salek-Ardakani, Dirk M Zajonc, Michael Croft

Front Immunol· September 2023

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Single-cell transcriptomes and T cell receptors of vaccine-expanded apolipoprotein B-specific T cells.
Felix Sebastian Nettersheim, Yanal Ghosheh, Holger Winkels, Kouji Kobiyama, Christopher Durant, Dirk M Zajonc

Front Cardiovasc Med· January 2023

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An Pipeline Identifying an HLA-A02:01 KRAS G12V Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients.
Michele Mishto, Artem Mansurkhodzhaev, Ge Ying, Aruna Bitra, Robert A Cordfunke, Dirk M Zajonc

Front Immunol· November 2020

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Structure-Function Implications of the Ability of Monoclonal Antibodies Against α-Galactosylceramide-CD1d Complex to Recognize β-Mannosylceramide Presentation by CD1d.
Katharine Clark, Jessica Yau, Anja Bloom, Jing Wang, David J Venzon, Dirk M Zajonc

Front Immunol· October 2020

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Unconventional Peptide Presentation by Classical MHC Class I and Implications for T and NK Cell Activation.
Dirk M Zajonc

Int J Mol Sci· October 2020

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Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin.
Espen Melum, Xiaojun Jiang, Kristi D Baker, M Fatima Macedo, Jürgen Fritsch, Dirk M Zajonc

Nat Immunol· December 2019

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A molecular switch in mouse CD1d modulates natural killer T cell activation by α-galactosylsphingamides.
Jing Wang, Joren Guillaume, Jonas Janssens, Soumya G Remesh, Ge Ying, Dirk M Zajonc

J Biol Chem· September 2019

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Catching a complex for optimal signaling.
Dirk M Zajonc

J Biol Chem· September 2019

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Structural basis of NKT cell inhibition using the T-cell receptor-blocking anti-CD1d antibody 1B1.
Ge Ying, Jing Wang, Thierry Mallevaey, Serge Van Calenbergh, Dirk M Zajonc

J Biol Chem· August 2019

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Structure of human cytomegalovirus UL144, an HVEM orthologue, bound to the B and T cell lymphocyte attenuator.
Aruna Bitra, Ivana Nemčovičová, Gaelle Picarda, Tzanko Doukov, Jing Wang, Dirk M Zajonc

J Biol Chem· July 2019

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Restriction of Human Cytomegalovirus Infection by Galectin-9.
Emily A Machala, Selmir Avdic, Lauren Stern, Dirk M Zajonc, Chris A Benedict

J Virol· February 2019

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Self-glycerophospholipids activate murine phospholipid-reactive T cells and inhibit iNKT cell activation by competing with ligands for CD1d loading.
Ramesh Chandra Halder, Cynthia Tran, Priti Prasad, Jing Wang, Dhiraj Nallapothula, Dirk M Zajonc

Eur J Immunol· February 2019

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Crystal structure of the m4-1BB/4-1BBL complex reveals an unusual dimeric ligand that undergoes structural changes upon 4-1BB receptor binding.
Aruna Bitra, Tzanko Doukov, Giuseppe Destito, Michael Croft, Dirk M Zajonc

J Biol Chem· February 2019

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4"-O-Alkylated α-Galactosylceramide Analogues as iNKT-Cell Antigens: Synthetic, Biological, and Structural Studies.
Jonas Janssens, Aruna Bitra, Jing Wang, Tine Decruy, Koen Venken, Dirk M Zajonc

ChemMedChem· January 2019

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High-Affinity Bent β-Integrin Molecules in Arresting Neutrophils Face Each Other through Binding to ICAMs In cis.
Zhichao Fan, William Bill Kiosses, Hao Sun, Marco Orecchioni, Yanal Ghosheh, Dirk M Zajonc

Cell Rep· January 2019

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Enhancing T cell responses and tumour immunity by vaccination with peptides conjugated to a weak NKT cell agonist.
Benjamin J Compton, Kathryn J Farrand, Ching-Wen Tang, Taryn L Osmond, Mary Speir, Dirk M Zajonc

Org Biomol Chem· January 2019

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Crystal structures of the human 4-1BB receptor bound to its ligand 4-1BBL reveal covalent receptor dimerization as a potential signaling amplifier.
Aruna Bitra, Tzanko Doukov, Michael Croft, Dirk M Zajonc

J Biol Chem· June 2018

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Characterization of murine antibody responses to vaccinia virus envelope protein A14 reveals an immunodominant antigen lacking of effective neutralization targets.
Xiangzhi Meng, Thomas Kaever, Bo Yan, Paula Traktman, Dirk M Zajonc

Virology· May 2018

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CD1c caves in on lipids.
Dirk M Zajonc

Nat Immunol· April 2018

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A ligand-specific blockade of the integrin Mac-1 selectively targets pathologic inflammation while maintaining protective host-defense.
Dennis Wolf, Nathaly Anto-Michel, Hermann Blankenbach, Ansgar Wiedemann, Konrad Buscher, Dirk M Zajonc

Nat Commun· February 2018

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Structure-function characterization of three human antibodies targeting the vaccinia virus adhesion molecule D8.
Michael H Matho, Andrew Schlossman, Iuliia M Gilchuk, Greg Miller, Zbigniew Mikulski, Dirk M Zajonc

J Biol Chem· January 2018

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Crystal structure of murine 4-1BB and its interaction with 4-1BBL support a role for galectin-9 in 4-1BB signaling.
Aruna Bitra, Tzanko Doukov, Jing Wang, Gaelle Picarda, Chris A Benedict, Dirk M Zajonc

J Biol Chem· January 2018

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Regulatory T Cell-Mediated Suppression of Inflammation Induced by DR3 Signaling Is Dependent on Galectin-9.
Shravan Madireddi, So-Young Eun, Amit K Mehta, Aruna Birta, Dirk M Zajonc

J Immunol· October 2017

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Crystal structure of Qa-1a with bound Qa-1 determinant modifier peptide.
Ge Ying, Jing Wang, Vipin Kumar, Dirk M Zajonc

PLoS One· September 2017

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Galactosylsphingamides: new α-GalCer analogues to probe the F'-pocket of CD1d.
Joren Guillaume, Jing Wang, Jonas Janssens, Soumya G Remesh, Martijn D P Risseeuw, Dirk M Zajonc

Sci Rep· June 2017

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