Publications by authors named "Dirk Remus"

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RNA polymerase II is a polar roadblock to a progressing DNA fork.
Taryn M Kay, James T Inman, Lucyna Lubkowska, Tung T Le, Jin Qian, Dirk Remus

Nat Commun· September 2025

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G-quadruplex-stalled eukaryotic replisome structure reveals helical inchworm DNA translocation.
Sahil Batra, Benjamin Allwein, Charanya Kumar, Sujan Devbhandari, Jan-Gert Brüning, Dirk Remus

Science· March 2025

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Looping out of control: R-loops in transcription-replication conflict.
Charanya Kumar, Dirk Remus

Chromosoma· January 2024

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A transcription-based approach to purify R-loop-containing plasmid DNA templates in vitro.
Charanya Kumar, Dirk Remus

STAR Protoc· March 2023

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A hypomorphic mutation in Pold1 disrupts the coordination of embryo size expansion and morphogenesis during gastrulation.
Tingxu Chen, Heather Alcorn, Sujan Devbhandari, Dirk Remus, Elizabeth Lacy

Biol Open· August 2022

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Yeast ORC sumoylation status fine-tunes origin licensing.
Gemma Regan-Mochrie, Timothy Hoggard, Nikhil Bhagwat, Gerard Lynch, Neil Hunter, Dirk Remus

Genes Dev· August 2022

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CMG helicase activity on G4-containing DNA templates.
Sahil Batra, Sujan Devbhandari, Dirk Remus

Methods Enzymol· August 2022

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Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Marina Schrecker, Juan C Castaneda, Sujan Devbhandari, Charanya Kumar, Dirk Remus

Elife· August 2022

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Mechanisms of loading and release of the 9-1-1 checkpoint clamp.
Juan C Castaneda, Marina Schrecker, Dirk Remus, Richard K Hite

Nat Struct Mol Biol· April 2022

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Mobile origin-licensing factors confer resistance to conflicts with RNA polymerase.
Matthias J Scherr, Syafiq Abd Wahab, Dirk Remus, Karl E Duderstadt

Cell Rep· March 2022

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Cdc6 is sequentially regulated by PP2A-Cdc55, Cdc14, and Sic1 for origin licensing in .
Jasmin Philip, Mihkel Örd, Andriele Silva, Shaneen Singh, John Fx Diffley, Dirk Remus

Elife· February 2022

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The interplay of RNA:DNA hybrid structure and G-quadruplexes determines the outcome of R-loop-replisome collisions.
Charanya Kumar, Sahil Batra, Jack D Griffith, Dirk Remus

Elife· September 2021

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Antagonistic control of DDK binding to licensed replication origins by Mcm2 and Rad53.
Syafiq Abd Wahab, Dirk Remus

Elife· July 2020

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Rad53 limits CMG helicase uncoupling from DNA synthesis at replication forks.
Sujan Devbhandari, Dirk Remus

Nat Struct Mol Biol· May 2020

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DNA polymerase ε relies on a unique domain for efficient replisome assembly and strand synthesis.
Xiangzhou Meng, Lei Wei, Sujan Devbhandari, Tuo Zhang, Jenny Xiang, Dirk Remus

Nat Commun· May 2020

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Checkpoint Kinase Rad53 Couples Leading- and Lagging-Strand DNA Synthesis under Replication Stress.
Haiyun Gan, Chuanhe Yu, Sujan Devbhandari, Sushma Sharma, Junhong Han, Dirk Remus

Mol Cell· October 2017

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Cdt1 stabilizes an open MCM ring for helicase loading.
Jordi Frigola, Jun He, Kerstin Kinkelin, Valerie E Pye, Ludovic Renault, Dirk Remus

Nat Commun· June 2017

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Chromatin Constrains the Initiation and Elongation of DNA Replication.
Sujan Devbhandari, Jieqing Jiang, Charanya Kumar, Iestyn Whitehouse, Dirk Remus

Mol Cell· January 2017

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Eukaryotic replication origins: Strength in flexibility.
Charanya Kumar, Dirk Remus

Nucleus· May 2016

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Post-licensing Specification of Eukaryotic Replication Origins by Facilitated Mcm2-7 Sliding along DNA.
Julien Gros, Charanya Kumar, Gerard Lynch, Tejas Yadav, Iestyn Whitehouse, Dirk Remus

Mol Cell· December 2015

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Origin plasticity during budding yeast DNA replication in vitro.
Julien Gros, Sujan Devbhandari, Dirk Remus

EMBO J· March 2014

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ATPase-dependent quality control of DNA replication origin licensing.
Jordi Frigola, Dirk Remus, Amina Mehanna, John F X Diffley

Nature· March 2013

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Eukaryotic DNA replication control: lock and load, then fire.
Dirk Remus, John F X Diffley

Curr Opin Cell Biol· December 2009

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Concerted loading of Mcm2-7 double hexamers around DNA during DNA replication origin licensing.
Dirk Remus, Fabienne Beuron, Gökhan Tolun, Jack D Griffith, Edward P Morris

Cell· November 2009

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CDK phosphorylation inhibits the DNA-binding and ATP-hydrolysis activities of the Drosophila origin recognition complex.
Dirk Remus, Marco Blanchette, Donald C Rio, Michael R Botchan

J Biol Chem· December 2005

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