Publications by authors named "Dirk Smith"

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Drug Repurposing: The Anthelmintics Niclosamide and Nitazoxanide Are Potent TMEM16A Antagonists That Fully Bronchodilate Airways.
Kent Miner, Katja Labitzke, Benxian Liu, Paul Wang, Kathryn Henckels, Dirk Smith

Front Pharmacol· February 2019

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IL-33 meets allergens at the gate.
Dirk E Smith

Nat Immunol· April 2018

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Large-scale gene expression profiling reveals distinct type 2 inflammatory patterns in chronic rhinosinusitis subtypes.
Matthew A Tyler, Chris B Russell, Dirk E Smith, James B Rottman, Caroline J Padro Dietz

J Allergy Clin Immunol· March 2017

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A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma.
Dirk Smith, Hannes Helgason, Patrick Sulem, Unnur Steina Bjornsdottir, Ai Ching Lim

PLoS Genet· March 2017

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IL-33 Drives Augmented Responses to Ozone in Obese Mice.
Joel A Mathews, Nandini Krishnamoorthy, David Itiro Kasahara, Youngji Cho, Allison Patricia Wurmbrand, Dirk Smith

Environ Health Perspect· February 2017

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Combinatorial targeting of TSLP, IL-25, and IL-33 in type 2 cytokine-driven inflammation and fibrosis.
Kevin M Vannella, Thirumalai R Ramalingam, Lee A Borthwick, Luke Barron, Kevin M Hart, Dirk E Smith

Sci Transl Med· May 2016

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IL-33 Drives Eosinophil Infiltration and Pathogenic Type 2 Helper T-Cell Immune Responses Leading to Chronic Experimental Ileitis.
Carlo De Salvo, Xiao-Ming Wang, Luca Pastorelli, Benedetta Mattioli, Sara Omenetti, Dirk E Smith

Am J Pathol· April 2016

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Research in progress: Medical Research Council United Kingdom Refractory Asthma Stratification Programme (RASP-UK).
Liam G Heaney, Ratko Djukanovic, Ashley Woodcock, Samantha Walker, John G Matthews, Dirk Smith

Thorax· February 2016

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Atherosclerosis severity is not affected by a deficiency in IL-33/ST2 signaling.
Praxedis Martin, Gaby Palmer, Emiliana Rodriguez, Estelle Woldt, Isabelle Mean, Dirk E Smith

Immun Inflamm Dis· September 2015

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A new mouse strain for the analysis of invariant NKT cell function.
Shilpi Chandra, Meng Zhao, Alison Budelsky, Alvaro de Mingo Pulido, Jeremy Day, Dirk Smith

Nat Immunol· August 2015

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The nucleotide-binding domain, leucine-rich repeat protein 3 inflammasome/IL-1 receptor I axis mediates innate, but not adaptive, immune responses after exposure to particulate matter under 10 μm.
Jeremy A Hirota, Matthew J Gold, Paul R Hiebert, Leigh G Parkinson, Tracee Wee, Dirk Smith

Am J Respir Cell Mol Biol· January 2015

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Increased density of intraepithelial mast cells in patients with exercise-induced bronchoconstriction regulated through epithelially derived thymic stromal lymphopoietin and IL-33.
Ying Lai, William A Altemeier, John Vandree, Adrian M Piliponsky, Brian Johnson, Dirk E Smith

J Allergy Clin Immunol· May 2014

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IL-33 mediates multi-walled carbon nanotube (MWCNT)-induced airway hyper-reactivity via the mobilization of innate helper cells in the lung.
Celine A Beamer, Teri A Girtsman, Benjamin P Seaver, Krissy J Finsaas, Christopher T Migliaccio, Dirk E Smith

Nanotoxicology· September 2013

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IL-33 drives biphasic IL-13 production for noncanonical Type 2 immunity against hookworms.
Li-Yin Hung, Ian P Lewkowich, Lucas A Dawson, Jordan Downey, Yanfen Yang, Dirk E Smith

Proc Natl Acad Sci U S A· January 2013

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Disease severity in K/BxN serum transfer-induced arthritis is not affected by IL-33 deficiency.
Praxedis Martin, Dominique Talabot-Ayer, Christian Alexander Seemayer, Solenne Vigne, Céline Lamacchia, Dirk E Smith

Arthritis Res Ther· January 2013

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Presensitizing with a Toll-like receptor 3 ligand impairs CD8 T-cell effector differentiation and IL-33 responsiveness.
Soo Mun Ngoi, Marie-Clare St Rose, Antoine M Menoret, Dirk E Smith, Michael G Tovey

Proc Natl Acad Sci U S A· June 2012

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Brain-specific interleukin-1 receptor accessory protein in sleep regulation.
Ping Taishi, Christopher J Davis, Omar Bayomy, Mark R Zielinski, Fan Liao, Dirk E Smith

J Appl Physiol (1985)· March 2012

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Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection.
Marsha Wills-Karp, Reena Rani, Krista Dienger, Ian Lewkowich, James G Fox, Dirk E Smith

J Exp Med· March 2012

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Innate lymphoid cells responding to IL-33 mediate airway hyperreactivity independently of adaptive immunity.
Hye Young Kim, Ya-Jen Chang, Srividya Subramanian, Hyun-Hee Lee, Lee A Albacker, Dirk E Smith

J Allergy Clin Immunol· January 2012

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Neuron-specific effects of interleukin-1β are mediated by a novel isoform of the IL-1 receptor accessory protein.
Yangyang Huang, Dirk E Smith, Osvaldo Ibáñez-Sandoval, John E Sims, Wilma J Friedman

J Neurosci· December 2011

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Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity.
Ya-Jen Chang, Hye Young Kim, Lee A Albacker, Nicole Baumgarth, Andrew N J McKenzie, Dirk E Smith

Nat Immunol· May 2011

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The biological paths of IL-1 family members IL-18 and IL-33.
Dirk E Smith

J Leukoc Biol· March 2011

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IL-1 family nomenclature.
Charles Dinarello, William Arend, John Sims, Dirk Smith, Hal Blumberg

Nat Immunol· November 2010

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The IL-1 family: regulators of immunity.
John E Sims, Dirk E Smith

Nat Rev Immunol· February 2010

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A central nervous system-restricted isoform of the interleukin-1 receptor accessory protein modulates neuronal responses to interleukin-1.
Dirk E Smith, Brian P Lipsky, Chris Russell, Randal R Ketchem, Jacqueline Kirchner

Immunity· June 2009

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