Publications by authors named "Disha Awasthy"

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Validation of whole genome sequencing from dried blood spots.
Pooja Agrawal, Shanmukh Katragadda, Arun K Hariharan, Vijayashree Gauribidanur Raghavendrachar, Arunika Agarwal, Disha Awasthy

BMC Med Genomics· April 2021

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Optimization of Compound Plate Preparation to Address Precipitation Issue in Mammalian A549 Cytotoxicity Assay.
Vijayashree Gauribidanur Raghavendra Achar, Shubhada Pramod Barde, Meenakshy Venkatesh Mallya, Disha Awasthy, Chandan Narayan

J Lab Autom· June 2016

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Discovery of benzothiazoles as antimycobacterial agents: Synthesis, structure-activity relationships and binding studies with Mycobacterium tuberculosis decaprenylphosphoryl-β-D-ribose 2'-oxidase.
Sudhir Landge, Amrita B Mullick, Kavitha Nagalapur, João Neres, Venkita Subbulakshmi, Disha Awasthy

Bioorg Med Chem· December 2015

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Genetic and chemical validation identifies Mycobacterium tuberculosis topoisomerase I as an attractive anti-tubercular target.
Sudha Ravishankar, Anisha Ambady, Disha Awasthy, Naina Vinay Mudugal, Sreenivasaiah Menasinakai

Tuberculosis (Edinb)· September 2015

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Whole cell screen based identification of spiropiperidines with potent antitubercular properties.
Subramanyam J Tantry, Giulia Degiacomi, Sreevalli Sharma, Lalit Kumar Jena, Ashwini Narayan, Disha Awasthy

Bioorg Med Chem Lett· August 2015

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Triaminopyrimidine is a fast-killing and long-acting antimalarial clinical candidate.
Shahul Hameed P, Suresh Solapure, Vikas Patil, Philipp P Henrich, Pamela A Magistrado, Disha Awasthy

Nat Commun· March 2015

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Revisiting the essentiality of glutamate racemase in Mycobacterium tuberculosis.
Sapna Morayya, Disha Awasthy, Reena Yadav, Anisha Ambady, Umender Sharma

Gene· January 2015

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Roles of the two type II NADH dehydrogenases in the survival of Mycobacterium tuberculosis in vitro.
Disha Awasthy, Anisha Ambady, Ashwini Narayana, Sapna Morayya, Umender Sharma

Gene· October 2014

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Optimization of pyrrolamides as mycobacterial GyrB ATPase inhibitors: structure-activity relationship and in vivo efficacy in a mouse model of tuberculosis.
Shahul Hameed P, Suresh Solapure, Kakoli Mukherjee, Vrinda Nandi, David Waterson, Disha Awasthy

Antimicrob Agents Chemother· September 2014

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Diarylthiazole: an antimycobacterial scaffold potentially targeting PrrB-PrrA two-component system.
Eknath Bellale, Maruti Naik, Varun V B, Anisha Ambady, Ashwini Narayan, Disha Awasthy

J Med Chem· August 2014

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N-aryl-2-aminobenzimidazoles: novel, efficacious, antimalarial lead compounds.
Sreekanth Ramachandran, Shahul Hameed P, Abhishek Srivastava, Gajanan Shanbhag, Sapna Morayya, Disha Awasthy

J Med Chem· August 2014

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Aminoazabenzimidazoles, a novel class of orally active antimalarial agents.
Shahul Hameed P, Murugan Chinnapattu, Gajanan Shanbag, Praveena Manjrekar, Krishna Koushik, Disha Awasthy

J Med Chem· July 2014

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Novel N-linked aminopiperidine-based gyrase inhibitors with improved hERG and in vivo efficacy against Mycobacterium tuberculosis.
Shahul Hameed P, Vikas Patil, Suresh Solapure, Umender Sharma, Prashanti Madhavapeddi, Disha Awasthy

J Med Chem· June 2014

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4-aminoquinolone piperidine amides: noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity.
Maruti Naik, Vaishali Humnabadkar, Subramanyam J Tantry, Manoranjan Panda, Ashwini Narayan, Disha Awasthy

J Med Chem· June 2014

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Azaindoles: noncovalent DprE1 inhibitors from scaffold morphing efforts, kill Mycobacterium tuberculosis and are efficacious in vivo.
Pravin S Shirude, Radha Shandil, Claire Sadler, Maruti Naik, Vinayak Hosagrahara, Disha Awasthy

J Med Chem· December 2013

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Evaluation of CoA biosynthesis proteins of Mycobacterium tuberculosis as potential drug targets.
Anisha Ambady, Disha Awasthy, Reena Yadav, Santhoshi Basuthkar, Kothandaraman Seshadri

Tuberculosis (Edinb)· November 2012

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Alanine racemase mutants of Mycobacterium tuberculosis require D-alanine for growth and are defective for survival in macrophages and mice.
Disha Awasthy, Sowmya Bharath, Venkita Subbulakshmi, Umender Sharma

Microbiology (Reading)· February 2012

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Essentiality and functional analysis of type I and type III pantothenate kinases of Mycobacterium tuberculosis.
Disha Awasthy, Anisha Ambady, Jyothi Bhat, Gulebahar Sheikh, Sudha Ravishankar

Microbiology (Reading)· September 2010

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Inactivation of the ilvB1 gene in Mycobacterium tuberculosis leads to branched-chain amino acid auxotrophy and attenuation of virulence in mice.
Disha Awasthy, Sheshagiri Gaonkar, R K Shandil, Reena Yadav, Sowmya Bharath

Microbiology (Reading)· September 2009

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