Publications by authors named "Dmitri Simberg"

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PEGylation technology: addressing concerns, moving forward.
Dmitri Simberg, Yechezkel Barenholz, Steve R Roffler, Katharina Landfester, Alexander V Kabanov

Drug Deliv· December 2025

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Role of Serum Stability and Lipoprotein Interactions in Lipid Structure-Tumor Accumulation Relationship.
Ashlynn Barnes, Hanmant K Gaikwad, David Siegel, David Angarita, Morgan Nebbia, Dmitri Simberg

ACS Nano· October 2025

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Bi-specific T cell-engaging antibody triggers protective immune memory and glioma microenvironment remodeling in immune-competent preclinical models.
Markella Zannikou, Joseph T Duffy, Daniele Procissi, Hinda Najem, Rebecca N Levine, Dmitri Simberg

J Immunother Cancer· October 2025

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Longitudinal Imaging Reveals Tumor Uptake and Prolonged Retention of Bispecific T Cell-Engaging Antibody in GBM via Passive and Active Mechanisms.
Yutian Feng, Benedikt Haupt, Truc T Huynh, Rebecca Meshaw, Angela Martin-Regalado, Dmitri Simberg

Clin Cancer Res· August 2025

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Magnetic Nanoworm-Based Screening of Yeast Library for Anti-PEG Nanobodies.
Shashikant Ray, Sarah Jacques, Utibeabasi Ettah, Shaodong Dai, Hanmant K Gaikwad, Dmitri Simberg

Mol Pharm· August 2025

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Pathotype-Specific Expression of Granzyme-Perforin Pathway Genes and Their Association With Clinical Disease Activity in Early Rheumatoid Arthritis and in a Randomized Clinical Trial.
Francisco G La Rosa, Larry W Moreland, Luigi Nibali, Mike Curtis, Kevin D Deane, Dmitri Simberg

Immune Netw· August 2025

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Enhanced immunocompatibility and hemocompatibility of nanomedicines across multiple species using complement pathway inhibitors.
Yue Li, Sarah Jacques, Hanmant Gaikwad, Morgan Nebbia, Nirmal K Banda, Dmitri Simberg

Sci Adv· July 2025

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Analysis of human factor H-related gene and protein expressed in rheumatoid arthritis synovium identifies a novel mechanism promoting dysregulated complement pathway activation.
Nirmal K Banda, Larry W Moreland, Kevin D Deane, Dmitri Simberg, Robert I Scheinman

Sci Rep· June 2025

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Nanogels conjugated with cell-penetrating peptide as drug delivery vehicle for treating urinary tract infections.
Humberto D Escobedo, Nicholas Zawadzki, James K A Till, Andres Vazquez-Torres, Guankui Wang, Dmitri Simberg

Nanomedicine· April 2025

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Nanoparticle-Binding Immunoglobulins Predict Variable Complement Responses in Healthy and Diseased Cohorts.
Yue Li, Laura Saba, Robert I Scheinman, Nirmal K Banda, Michael Holers, Dmitri Simberg

ACS Nano· October 2024

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Optimized Enzyme-Linked Immunosorbent Assay for Anti-PEG Antibody Detection in Healthy Donors and Patients Treated with PEGylated Liposomal Doxorubicin.
Yue Li, Utibeabasi Ettah, Sarah Jacques, Hanmant Gaikwad, Andrew Monte, Dmitri Simberg

Mol Pharm· June 2024

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Mechanisms and Barriers in Nanomedicine: Progress in the Field and Future Directions.
Thomas Anchordoquy, Natalie Artzi, Irina V Balyasnikova, Yechezkel Barenholz, Ninh M La-Beck, Dmitri Simberg

ACS Nano· June 2024

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Validation of dot blot immunoassay for measurement of complement opsonization of nanoparticles.
Yue Li, Andrew Monte, Layne Dylla, S Moein Moghimi, Dmitri Simberg

J Immunol Methods· May 2024

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Decay-Accelerating Factor Differentially Associates With Complement-Mediated Damage in Synovium After Meniscus Tear as Compared to Anterior Cruciate Ligament Injury.
V Michael Holers, Rachel M Frank, Michael Zuscik, Carson Keeter, Robert I Scheinman, Dmitri Simberg

Immune Netw· April 2024

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Inhibition of acute complement responses towards bolus-injected nanoparticles using targeted short-circulating regulatory proteins.
Yue Li, Sarah Jacques, Hanmant Gaikwad, Guankui Wang, Nirmal K Banda, Dmitri Simberg

Nat Nanotechnol· February 2024

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Complement-dependent uptake of nanoparticles by blood phagocytes: brief overview and perspective.
Yue Li, Seyed Moein Moghimi, Dmitri Simberg

Curr Opin Biotechnol· February 2024

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Activation of the complement system by nanoparticles and strategies for complement inhibition.
Hajira B Haroon, Elisha Dhillon, Z Shadi Farhangrazi, Panagiotis N Trohopoulos, Dmitri Simberg

Eur J Pharm Biopharm· December 2023

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Perspectives on complement and phagocytic cell responses to nanoparticles: From fundamentals to adverse reactions.
S Moein Moghimi, Hajira B Haroon, Anan Yaghmur, A Christy Hunter, Emanuele Papini, Dmitri Simberg

J Control Release· April 2023

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Revisiting nanoparticle transendothelial migration in the liver.
Seyed Moein Moghimi, Rebecca McCullough, Dmitri Simberg

Mol Ther· March 2023

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Nanometer- and angstrom-scale characteristics that modulate complement responses to nanoparticles.
S Moein Moghimi, Hajira B Haroon, Anan Yaghmur, Dmitri Simberg, Panagiotis N Trohopoulos

J Control Release· November 2022

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Indocarbocyanine nanoparticles extravasate and distribute better than liposomes in brain tumors.
Irina V Balyasnikova, Markella Zannikou, Guankui Wang, Yue Li, Joseph T Duffy, Dmitri Simberg

J Control Release· September 2022

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Surface Modification of Erythrocytes with Lipid Anchors: Structure-Activity Relationship for Optimal Membrane Incorporation, in vivo Retention, and Immunocompatibility.
Hanmant Gaikwad, Guankui Wang, Yue Li, David Bourne, Dmitri Simberg

Adv Nanobiomed Res· August 2022

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Pro-inflammatory concerns with lipid nanoparticles.
Seyed Moein Moghimi, Dmitri Simberg

Mol Ther· June 2022

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Antibody-Dependent Complement Responses toward SARS-CoV-2 Receptor-Binding Domain Immobilized on "Pseudovirus-like" Nanoparticles.
Hanmant Gaikwad, Yue Li, Guankui Wang, Ronghui Li, Shaodong Dai, Dmitri Simberg

ACS Nano· May 2022

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PEGylated Liposomes Accumulate in the Areas Relevant to Skin Toxicities Passive Extravasation across "Leaky" Endothelium.
Yue Li, Laren Lofchy, Guankui Wang, Hanmant Gaikwad, Mayumi Fujita, Dmitri Simberg

ACS Nano· April 2022

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