Publications by authors named "Kevin D Deane"

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Risk factors for interstitial lung disease in early rheumatoid arthritis and external validation of screening strategies: a cross-sectional analysis of the prospective SAIL-RA cohort in the USA.
Gregory C McDermott, Ritu Gill, Suzanne Byrne, Staci Gagne, Xiaosong Wang, Kevin D Deane

Lancet Rheumatol· December 2025

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Understanding the Resolution of Clinically Suspect Arthralgia: Moving Forward, but Challenges Remain.
Kevin D Deane

J Rheumatol· December 2025

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Senescent Activated Naive B Cells Promote Anti-Citrullinated Antigen T Cell Responses and the Transition to Clinical Rheumatoid Arthritis.
Xiaohao Wu, Mengrui Zhang, Jae-Seung Moon, Eun Kyung Song, Joshua C Abrams, Kevin D Deane

bioRxiv· October 2025

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Serum Proteomic Signatures Before the Diagnosis of Rheumatoid Arthritis: Evolving Biologic Pathways and Specific Periods of Disease Development.
Samir Rachid Zaim, Adam K Savage, Mark A Gillespie, Jazmine D Castillo, Christy Bennett, Kevin D Deane

Arthritis Rheumatol· September 2025

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EULAR/ACR risk stratification criteria for development of rheumatoid arthritis in the risk stage of arthralgia.
Hanna W van Steenbergen, Frank Doornkamp, Stefano Alivernini, John Backlund, Catalin Codreanu, Kevin D Deane

Ann Rheum Dis· September 2025

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Progression to rheumatoid arthritis in at-risk individuals is defined by systemic inflammation and by T and B cell dysregulation.
Ziyuan He, Marla C Glass, Pravina Venkatesan, Marie L Feser, Leander Lazaro, Kevin D Deane

Sci Transl Med· September 2025

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TNF-α impairs platelet function by inhibiting autophagy and disrupting metabolism via syntaxin 17 downregulation.
Guadalupe Rojas-Sanchez, Jorge Calzada-Martinez, Brandon McMahon, Aaron C Petrey, Gabriela Dveksler, Kevin D Deane

J Clin Invest· August 2025

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A phase 2 trial of hydroxychloroquine in individuals at risk for rheumatoid arthritis.
Kevin D Deane, Christopher C Striebich, Marie L Feser, James R O'Dell, Judith A James

Arthritis Rheumatol· August 2025

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Pathotype-Specific Expression of Granzyme-Perforin Pathway Genes and Their Association With Clinical Disease Activity in Early Rheumatoid Arthritis and in a Randomized Clinical Trial.
Francisco G La Rosa, Larry W Moreland, Luigi Nibali, Mike Curtis, Kevin D Deane

Immune Netw· August 2025

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Transforming growth factor-beta is increased in sputum from individuals with rheumatoid arthritis-associated pulmonary fibrosis.
Timothy M Wilson, Matthew Bolt, Andrew Stahly, Joyce S Lee, Tami J Bang, Kevin D Deane

Rheumatology (Oxford)· June 2025

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Analysis of human factor H-related gene and protein expressed in rheumatoid arthritis synovium identifies a novel mechanism promoting dysregulated complement pathway activation.
Nirmal K Banda, Larry W Moreland, Kevin D Deane, Dmitri Simberg, Robert I Scheinman

Sci Rep· June 2025

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EULAR/American College of Rheumatology Risk Stratification Criteria for Development of Rheumatoid Arthritis in the Risk Stage of Arthralgia.
Hanna W van Steenbergen, Frank Doornkamp, Stefano Alivernini, John Backlund, Catalin Codreanu, Kevin D Deane

Arthritis Rheumatol· May 2025

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Deep immunophenotyping reveals circulating activated lymphocytes in individuals at risk for rheumatoid arthritis.
Jun Inamo, Joshua Keegan, Alec Griffith, Tusharkanti Ghosh, Alice Horisberger, Kevin D Deane

J Clin Invest· March 2025

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Airways Abnormalities in a Prospective Cohort of Patients With Rheumatoid Arthritis.
Scott M Matson, Jiwoong Choi, Drayton Rorah, Shamir Khan, Anna Trofimoff, Kevin D Deane

Chest· February 2025

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Multi-lineage transcriptional and cell communication signatures define pathways in individuals at-risk for developing rheumatoid arthritis that initiate and perpetuate disease.
Cong Liu, E Barton Prideaux, Peiyao Wu, David L Boyle, Amy Westermann, Kevin D Deane

bioRxiv· February 2025

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Epigenetic trajectory predicts development of clinical rheumatoid arthritis in ACPA+ individuals: Targeting Immune Responses for Prevention of Rheumatoid Arthritis (TIP-RA).
E Barton Prideaux, David L Boyle, Eunice Choi, Jane H Buckner, William H Robinson, Kevin D Deane

bioRxiv· January 2025

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Therapeutic interception in individuals at risk of rheumatoid arthritis to prevent clinically impactful disease.
Kevin D Deane, V Michael Holers, Paul Emery, Kulveer Mankia, Hani El-Gabalawy

Ann Rheum Dis· January 2025

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Risk factors for interstitial lung disease in early rheumatoid arthritis and external validation of screening strategies: Baseline results of SAIL-RA.
Gregory C McDermott, Ritu Gill, Suzanne Byrne, Staci Gagne, Xiaosong Wang, Kevin D Deane

medRxiv· January 2025

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Are There Disease Endotypes in Axial Spondyloarthritis and How Would We Define Them?
Kevin D Deane, Laura T Donlin, Christopher T Ritchlin, Kristine A Kuhn

J Rheumatol· December 2024

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New insights into which ACPA-positive individuals will develop clinical rheumatoid arthritis.
Kevin D Deane

Rheumatology (Oxford)· November 2024

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Systemic inflammation and lymphocyte activation precede rheumatoid arthritis.
Ziyuan He, Marla C Glass, Pravina Venkatesan, Marie L Feser, Leander Lazaro, Kevin D Deane

bioRxiv· November 2024

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Distinct mucosal endotypes as initiators and drivers of rheumatoid arthritis.
V Michael Holers, Kristen M Demoruelle, Jane H Buckner, Eddie A James, Gary S Firestein, Kevin D Deane

Nat Rev Rheumatol· October 2024

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Multi-Autoantibody Testing Identifies Expansion of Reactivity to Targeted Antigens Before a Diagnosis of Rheumatoid Arthritis.
Salina H Goff, Dylan T Bergstedt, Marie L Feser, LauraKay Moss, Ted R Mikuls, Kevin D Deane

ACR Open Rheumatol· September 2024

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Serum levels of B-cell activating factor are associated with a reduced risk of chronic lymphocytic leukemia.
Eleanor Frost, Jonathan N Hofmann, Wen-Yi Huang, Ashley A Frazer-Abel, Kevin D Deane

Blood Cancer J· August 2024

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A comparison of anti-cyclic citrullinated peptides (CCP3 and CCP3.1) autoantibody tests in rheumatoid arthritis.
Heather A Nelson, Dipanwita Banerjee, Camille L Novis, Kevin D Deane, Marie L Feser

Pract Lab Med· August 2024

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