Publications by authors named "Dominique Vaur"

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Long-term patient-derived ovarian cancer organoids closely recapitulate tumor of origin and clinical response.
Lucie Thorel, Enora Dolivet, Pierre-Marie Morice, Romane Florent, Jordane Divoux, Dominique Vaur

J Exp Clin Cancer Res· October 2025

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Deciphering dual clinical entities associated with TP53 pathogenic variants: Insights from 53,085 HBOC panel analyses in French laboratories.
Edwige Kasper, Flavie Boulouard, Noémie Basset, Lisa Golmard, Hela Sassi, Dominique Vaur

Int J Cancer· September 2025

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Automated Scoring to Assess RAD51-Mediated Homologous Recombination in Ovarian Patient-Derived Tumor Organoids.
Lucie Thorel, Nicolas Elie, Pierre-Marie Morice, Louis-Bastien Weiswald, Romane Florent, Dominique Vaur

Lab Invest· April 2025

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Fine mapping of RNA isoform diversity using an innovative targeted long-read RNA sequencing protocol with novel dedicated bioinformatics pipeline.
Camille Aucouturier, Nicolas Soirat, Laurent Castéra, Denis Bertrand, Alexandre Atkinson, Dominique Vaur

BMC Genomics· September 2024

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The OVAREX study: Establishment of ex vivo ovarian cancer models to validate innovative therapies and to identify predictive biomarkers.
Lucie Thorel, Jordane Divoux, Justine Lequesne, Guillaume Babin, Pierre-Marie Morice, Dominique Vaur

BMC Cancer· June 2024

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Validation of the Clinical Use of GIScar, an Academic-developed Genomic Instability Score Predicting Sensitivity to Maintenance Olaparib for Ovarian Cancer.
Raphaël Leman, Etienne Muller, Angelina Legros, Nicolas Goardon, Imène Chentli, Dominique Vaur

Clin Cancer Res· November 2023

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The TRIPLEX study: use of patient-derived tumor organoids as an innovative tool for precision medicine in triple-negative breast cancer.
Jordane Divoux, Romane Florent, Margaux Jacobs, Justine Lequesne, Jean-Michel Grellard, Dominique Vaur

BMC Cancer· September 2023

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ORGAVADS: establishment of tumor organoids from head and neck squamous cell carcinoma to assess their response to innovative therapies.
Marion Perréard, Romane Florent, Jordane Divoux, Jean-Michel Grellard, Justine Lequesne, Dominique Vaur

BMC Cancer· March 2023

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Association and performance of polygenic risk scores for breast cancer among French women presenting or not a familial predisposition to the disease.
Yue Jiao, Thérèse Truong, Séverine Eon-Marchais, Noura Mebirouk, Sandrine M Caputo, Dominique Vaur

Eur J Cancer· January 2023

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SPiP: Splicing Prediction Pipeline, a machine learning tool for massive detection of exonic and intronic variant effects on mRNA splicing.
Raphaël Leman, Béatrice Parfait, Dominique Vidaud, Emmanuelle Girodon, Laurence Pacot, Dominique Vaur

Hum Mutat· December 2022

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Perioperative treatment in resectable gastric cancer with spartalizumab in combination with fluorouracil, leucovorin, oxaliplatin and docetaxel (FLOT): a phase II study (GASPAR).
Mélanie Dos Santos, Justine Lequesne, Alexandra Leconte, Stéphane Corbinais, Aurélie Parzy, Dominique Vaur

BMC Cancer· May 2022

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Outcomes of Patients with Metastatic Castration-Resistant Prostate Cancer According to Somatic Damage DNA Repair Gene Alterations.
Zoé Neviere, Elodie Coquan, Pierre-Emmanuel Brachet, Emeline Meriaux, Isabelle Bonnet, Dominique Vaur

Curr Oncol· April 2022

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Diagnostic histologique et moléculaire des cancers de l'ovaire - recommandations pour la pratique clinique Saint-Paul 2021: Histological and molecular diagnosis of ovarian.
Catherine Genestie, Laurence Gladieff, Marie-Aude Le Frère-Belda, Alain Lortholary, Dominique Vaur

Bull Cancer· December 2021

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Classification of 101 BRCA1 and BRCA2 variants of uncertain significance by cosegregation study: A powerful approach.
Sandrine M Caputo, Lisa Golmard, Mélanie Léone, Francesca Damiola, Marine Guillaud-Bataille, Dominique Vaur

Am J Hum Genet· October 2021

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Concordance Between Tumor and Germline BRCA Status in High-Grade Ovarian Carcinoma Patients in the Phase III PAOLA-1/ENGOT-ov25 Trial.
Céline Callens, Dominique Vaur, Isabelle Soubeyran, Etienne Rouleau, Pierre-Alexandre Just

J Natl Cancer Inst· July 2021

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Identifying patients eligible for PARP inhibitor treatment: from NGS-based tests to 3D functional assays.
Pierre-Marie Morice, Elodie Coquan, Louis-Bastien Weiswald, Bernard Lambert, Dominique Vaur

Br J Cancer· July 2021

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TUMOSPEC: A Nation-Wide Study of Hereditary Breast and Ovarian Cancer Families with a Predicted Pathogenic Variant Identified through Multigene Panel Testing.
Fabienne Lesueur, Séverine Eon-Marchais, Sarah Bonnet-Boissinot, Juana Beauvallet, Marie-Gabrielle Dondon, Dominique Vaur

Cancers (Basel)· July 2021

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Diagnostic and prognostic value of a 7-panel mutation testing in thyroid nodules with indeterminate cytology: the SWEETMAC study.
Stéphane Bardet, Nicolas Goardon, Justine Lequesne, Dominique Vaur, Renaud Ciappuccini

Endocrine· February 2021

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Phase II study of concomitant radiotherapy with atezolizumab in oligometastatic soft tissue sarcomas: STEREOSARC trial protocol.
Jennifer le Guevelou, Colin Debaigt, Esma Saada-Bouzid, Julien Viotti, Nazim Khalladi, Dominique Vaur

BMJ Open· September 2020

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Tumor burden of persistent disease in patients with differentiated thyroid cancer: correlation with postoperative risk-stratification and impact on outcome.
Renaud Ciappuccini, Natacha Heutte, Audrey Lasne-Cardon, Virginie Saguet-Rysanek, Camille Leroy, Dominique Vaur

BMC Cancer· August 2020

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XAF1 as a modifier of p53 function and cancer susceptibility.
Emilia M Pinto, Bonald C Figueiredo, Wenan Chen, Henrique C R Galvao, Maria Nirvana Formiga, Dominique Vaur

Sci Adv· June 2020

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SpliceLauncher: a tool for detection, annotation and relative quantification of alternative junctions from RNAseq data.
Raphaël Leman, Valentin Harter, Alexandre Atkinson, Grégoire Davy, Antoine Rousselin, Dominique Vaur

Bioinformatics· March 2020

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Assessment of branch point prediction tools to predict physiological branch points and their alteration by variants.
Raphaël Leman, Hélène Tubeuf, Sabine Raad, Isabelle Tournier, Céline Derambure, Dominique Vaur

BMC Genomics· January 2020

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Alternative splicing and ACMG-AMP-2015-based classification of PALB2 genetic variants: an ENIGMA report.
Irene Lopez-Perolio, Raphaël Leman, Raquel Behar, Vanessa Lattimore, John F Pearson, Dominique Vaur

J Med Genet· July 2019

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GEMO, a National Resource to Study Genetic Modifiers of Breast and Ovarian Cancer Risk in and Pathogenic Variant Carriers.
Fabienne Lesueur, Noura Mebirouk, Yue Jiao, Laure Barjhoux, Muriel Belotti, Dominique Vaur

Front Oncol· October 2018

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