Publications by authors named "Donald L Price"

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Acute Presentation of Newly Diagnosed Multiple Sclerosis Associated With Polymerase Chain Reaction-Proven Human Herpesvirus 6 Central Nervous System Infection.
Conor M Pumphrey, Joshua F Scarcella, Donald L Price

Cureus· April 2022

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Rodent models of TDP-43: recent advances.
William Tsao, Yun Ha Jeong, Sophie Lin, Jonathan Ling, Donald L Price

Brain Res· June 2012

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Increased expression of PS1 is sufficient to elevate the level and activity of γ-secretase in vivo.
Tong Li, Yue-Ming Li, Kwangwook Ahn, Donald L Price, Sangram S Sisodia

PLoS One· April 2012

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Specific domains in anterior pharynx-defective 1 determine its intramembrane interactions with nicastrin and presenilin.
Po-Min Chiang, Ryan R Fortna, Donald L Price, Tong Li, Philip C Wong

Neurobiol Aging· February 2012

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Arc/Arg3.1 regulates an endosomal pathway essential for activity-dependent β-amyloid generation.
Jing Wu, Ronald S Petralia, Hideaki Kurushima, Hiral Patel, Mi-young Jung, Donald L Price

Cell· October 2011

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Passive (amyloid-β) immunotherapy attenuates monoaminergic axonal degeneration in the AβPPswe/PS1dE9 mice.
Ying Liu, Michael K Lee, Maria M James, Donald L Price, David R Borchelt

J Alzheimers Dis· May 2011

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Reduced BACE1 activity enhances clearance of myelin debris and regeneration of axons in the injured peripheral nervous system.
Mohamed H Farah, Bao Han Pan, Paul N Hoffman, Dana Ferraris, Takashi Tsukamoto, Donald L Price

J Neurosci· April 2011

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Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism.
Po-Min Chiang, Jonathan Ling, Yun Ha Jeong, Donald L Price, Susan M Aja

Proc Natl Acad Sci U S A· September 2010

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Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice.
Xiu Shan, Po-Min Chiang, Donald L Price, Philip C Wong

Proc Natl Acad Sci U S A· September 2010

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Neuropathologic studies of the Baltimore Longitudinal Study of Aging (BLSA).
Richard J O'Brien, Susan M Resnick, Alan B Zonderman, Luigi Ferrucci, Barbara J Crain, Donald L Price

J Alzheimers Dis· June 2010

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Modeling an anti-amyloid combination therapy for Alzheimer's disease.
Vivian W Chow, Alena V Savonenko, Tatiana Melnikova, Hyunsu Kim, Donald L Price

Sci Transl Med· January 2010

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Amyloid pathology is associated with progressive monoaminergic neurodegeneration in a transgenic mouse model of Alzheimer's disease.
Ying Liu, Mi-Jeong Yoo, Alena Savonenko, Wanda Stirling, Donald L Price

J Neurosci· December 2008

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Progressive behavioral deficits in DJ-1-deficient mice are associated with normal nigrostriatal function.
Jayanth S Chandran, Xian Lin, Agustin Zapata, Ahmet Höke, Mika Shimoji, Donald L Price

Neurobiol Dis· March 2008

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Motor neuron disease occurring in a mutant dynactin mouse model is characterized by defects in vesicular trafficking.
Fiona M Laird, Mohamed H Farah, Steven Ackerley, Ahmet Hoke, Nicholas Maragakis, Donald L Price

J Neurosci· February 2008

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Epidermal growth factor receptor and notch pathways participate in the tumor suppressor function of gamma-secretase.
Tong Li, Hongjin Wen, Cory Brayton, Pritam Das, Lisa A Smithson, Donald L Price

J Biol Chem· November 2007

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Moderate reduction of gamma-secretase attenuates amyloid burden and limits mechanism-based liabilities.
Tong Li, Hongjin Wen, Cory Brayton, Fiona M Laird, Guojun Ma, Donald L Price

J Neurosci· October 2007

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The etiopathogenesis of Parkinson disease and suggestions for future research. Part I.
Irene Litvan, Glenda Halliday, Mark Hallett, Christopher G Goetz, Walter Rocca, Donald L Price

J Neuropathol Exp Neurol· April 2007

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Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking.
Chen Lai, Chengsong Xie, Stefanie G McCormack, Hsueh-Cheng Chiang, Marta K Michalak, Donald L Price

J Neurosci· November 2006

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Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death.
Lee J Martin, Yan Pan, Ann C Price, Wanda Sterling, Neal G Copeland, Donald L Price

J Neurosci· January 2006

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BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions.
Fiona M Laird, Huaibin Cai, Alena V Savonenko, Mohamed H Farah, Kaiwen He, Donald L Price

J Neurosci· December 2005

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Loss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress.
Huaibin Cai, Xian Lin, Chengsong Xie, Fiona M Laird, Chen Lai, Donald L Price

J Neurosci· August 2005

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Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities.
Alena Savonenko, Guilian M Xu, Tatiana Melnikova, Johanna L Morton, Victoria Gonzales, Donald L Price

Neurobiol Dis· April 2005

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Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: revisited.
Orly Lazarov, Gerardo A Morfini, Edward B Lee, Mohamed H Farah, Anita Szodorai, Donald L Price

J Neurosci· March 2005

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Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations.
Wenxue Li, Neva West, Emanuela Colla, Olga Pletnikova, Juan C Troncoso, Donald L Price

Proc Natl Acad Sci U S A· February 2005

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APH-1a is the principal mammalian APH-1 isoform present in gamma-secretase complexes during embryonic development.
Guojun Ma, Tong Li, Donald L Price, Philip C Wong

J Neurosci· January 2005

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