Publications by authors named "Donna Mendrick"

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Potential value of animal microphysiological systems.
Paul C Brown, Barry H Hooberman, Brianna L Skinner, Claudia Wrzesinski, Dayton M Petibone, Donna L Mendrick

ALTEX· October 2025

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Considerations from the pharmaceutical industry (IQ MPS Affiliate) workshop on animal microphysiological systems and 3Rs in drug development.
Patrick J Devine, Manti Guha, Jason E Ekert, Anna K Kopec, James R Gosset, Donna Mendrick

ALTEX· July 2025

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Biology-inspired dynamic microphysiological system approaches to revolutionize basic research, healthcare and animal welfare.
Uwe Marx, Sonja Beken, Zaozao Chen, Eva-Maria Dehne, Ann Doherty, Donna L Mendrick

ALTEX· April 2025

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Protecting Human and Animal Health: The Road from Animal Models to New Approach Methods.
Barbara L F Kaplan, Alan M Hoberman, William Slikker, Mary Alice Smith, Emanuela Corsini, Donna L Mendrick

Pharmacol Rev· February 2024

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Gaps and challenges in nonclinical assessments of pharmaceuticals: An FDA/CDER perspective on considerations for development of new approach methodologies.
Amy M Avila, Ilona Bebenek, Donna L Mendrick, Jackye Peretz, Jia Yao

Regul Toxicol Pharmacol· March 2023

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Co-Culture of Human Primary Hepatocytes and Nonparenchymal Liver Cells in the Emulate® Liver-Chip for the Study of Drug-Induced Liver Injury.
Qiang Shi, Ayesha Arefin, Lijun Ren, Katy S Papineau, Dustyn A Barnette, Donna L Mendrick

Curr Protoc· July 2022

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Perspectives on the evaluation and adoption of complex in vitro models in drug development: Workshop with the FDA and the pharmaceutical industry (IQ MPS Affiliate).
Szczepan W Baran, Paul C Brown, Andreas R Baudy, Suzanne C Fitzpatrick, Christopher Frantz, Donna L Mendrick

ALTEX· April 2022

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Biology-inspired microphysiological systems to advance patient benefit and animal welfare in drug development.
Uwe Marx, Takafumi Akabane, Tommy B Andersson, Elizabeth Baker, Mario Beilmann, Donna L Mendrick

ALTEX· July 2021

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FutureTox IV Workshop Summary: Predictive Toxicology for Healthy Children.
Thomas B Knudsen, Suzanne Compton Fitzpatrick, K Nadira De Abrew, Linda S Birnbaum, Anne Chappelle, Donna L Mendrick

Toxicol Sci· April 2021

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An FDA/CDER perspective on nonclinical testing strategies: Classical toxicology approaches and new approach methodologies (NAMs).
Amy M Avila, Ilona Bebenek, Jessica A Bonzo, Todd Bourcier, Karen L Davis Bruno, Donna L Mendrick

Regul Toxicol Pharmacol· July 2020

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The Gut Microbiome and Xenobiotics: Identifying Knowledge Gaps.
Vicki L Sutherland, Charlene A McQueen, Donna Mendrick, Donna Gulezian, Carl Cerniglia

Toxicol Sci· July 2020

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"Natural" is not synonymous with "Safe": Toxicity of natural products alone and in combination with pharmaceutical agents.
Tyler E Gaston, Donna L Mendrick, Mary F Paine, Amy L Roe, Catherine K Yeung

Regul Toxicol Pharmacol· June 2020

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The US Federal Tox21 Program: A strategic and operational plan for continued leadership.
Russell S Thomas, Richard S Paules, Anton Simeonov, Suzanne C Fitzpatrick, Kevin M Crofton, Donna L Mendrick

ALTEX· October 2018

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Metabolic Syndrome and Associated Diseases: From the Bench to the Clinic.
Donna L Mendrick, Anna Mae Diehl, Lisa S Topor, Rodney R Dietert, Yvonne Will

Toxicol Sci· March 2018

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A hybrid gene selection approach to create the S1500+ targeted gene sets for use in high-throughput transcriptomics.
Deepak Mav, Ruchir R Shah, Brian E Howard, Scott S Auerbach, Pierre R Bushel, Donna L Mendrick

PLoS One· March 2018

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Molecular Docking for Identification of Potential Targets for Drug Repurposing.
Heng Luo, William Mattes, Donna L Mendrick, Huixiao Hong

Curr Top Med Chem· February 2017

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FutureTox III: Bridges for Translation.
Daland R Juberg, Thomas B Knudsen, Miriam Sander, Nancy B Beck, Elaine M Faustman, Donna L Mendrick

Toxicol Sci· January 2017

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Proteomic analysis of acetaminophen-induced hepatotoxicity and identification of heme oxygenase 1 as a potential plasma biomarker of liver injury.
Yuan Gao, Zhijun Cao, Xi Yang, Mohamed A Abdelmegeed, Jinchun Sun, Donna L Mendrick

Proteomics Clin Appl· January 2017

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The Next Generation of Risk Assessment Multi-Year Study-Highlights of Findings, Applications to Risk Assessment, and Future Directions.
Ila Cote, Melvin E Andersen, Gerald T Ankley, Stanley Barone, Linda S Birnbaum, Donna Mendrick

Environ Health Perspect· November 2016

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Translating extracellular microRNA into clinical biomarkers for drug-induced toxicity: from high-throughput profiling to validation.
Wenjun Wang, Qiang Shi, Williams B Mattes, Donna L Mendrick, Xi Yang

Biomark Med· August 2016

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Biomarker-based drug safety assessment in the age of systems pharmacology: from foundational to regulatory science.
Chen Zhang, Huixiao Hong, Donna L Mendrick, Yun Tang, Feixiong Cheng

Biomark Med· August 2016

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Circulating mitochondrial biomarkers for drug-induced liver injury.
Qiang Shi, Xi Yang, William B Mattes, Donna L Mendrick, Alison H Harrill

Biomark Med· August 2016

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sNebula, a network-based algorithm to predict binding between human leukocyte antigens and peptides.
Heng Luo, Hao Ye, Hui Wen Ng, Sugunadevi Sakkiah, Donna L Mendrick

Sci Rep· August 2016

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Adverse outcome pathways: From research to regulation scientific workshop report.
Nicole C Kleinstreuer, Kristie Sullivan, David Allen, Stephen Edwards, Donna L Mendrick

Regul Toxicol Pharmacol· April 2016

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Machine Learning Methods for Predicting HLA-Peptide Binding Activity.
Heng Luo, Hao Ye, Hui Wen Ng, Leming Shi, Weida Tong, Donna L Mendrick

Bioinform Biol Insights· October 2015

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