Publications by authors named "Donna Small"

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SLPI deficiency alters airway protease activity and induces cell recruitment in a model of muco-obstructive lung disease.
Ryan Brown, Caoifa Dougan, Peter Ferris, Rebecca Delaney, Claire J Houston, Donna Small

Front Immunol· September 2024

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PTEN Depletion Increases Radiosensitivity in Response to Ataxia Telangiectasia-Related-3 (ATR) Inhibition in Non-Small Cell Lung Cancer (NSCLC).
Victoria L Dunne, Mihaela Ghita-Pettigrew, Kelly M Redmond, Donna M Small, Sinéad Weldon

Int J Mol Sci· July 2024

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Activation of innate-adaptive immune machinery by poly(I:C) exposes a therapeutic vulnerability to prevent relapse in stroma-rich colon cancer.
Shania M Corry, Amy Mb McCorry, Tamsin Rm Lannagan, Niamh A Leonard, Natalie C Fisher, Donna M Small

Gut· December 2022

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Secretory Leucoprotease Inhibitor (SLPI) Promotes Survival during Acute Infection by Suppression of Inflammation Rather Than Microbial Killing.
Megan Osbourn, Aoife M Rodgers, Alice V Dubois, Donna M Small, Fiachra Humphries

Biomolecules· November 2022

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Cathepsin S Contributes to Lung Inflammation in Acute Respiratory Distress Syndrome.
Michael C McKelvey, Anthony A Abladey, Donna M Small, Declan F Doherty, Richard Williams

Am J Respir Crit Care Med· April 2022

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Therapeutic Inhibition of Cathepsin S Reduces Inflammation and Mucus Plugging in Adult ENaC-Tg Mice.
Ryan Brown, Donna M Small, Declan F Doherty, Leslie Holsinger, Robert Booth

Mediators Inflamm· March 2022

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IL4Rα Signaling Abrogates Hypoxic Neutrophil Survival and Limits Acute Lung Injury Responses .
Alison J Harris, Ananda S Mirchandani, Ruairi W Lynch, Fiona Murphy, Liam Delaney, Donna Small

Am J Respir Crit Care Med· July 2019

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Preclinical Evaluation of Dose-Volume Effects and Lung Toxicity Occurring In and Out-of-Field.
Mihaela Ghita, Victoria L Dunne, Stephen J McMahon, Sarah O Osman, Donna M Small

Int J Radiat Oncol Biol Phys· April 2019

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Targeting of cathepsin S reduces cystic fibrosis-like lung disease.
Donna M Small, Ryan R Brown, Declan F Doherty, Anthony Abladey, Zhe Zhou-Suckow

Eur Respir J· March 2019

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Clearance of intracellular Klebsiella pneumoniae infection using gentamicin-loaded nanoparticles.
Lai Jiang, Michelle K Greene, Jose Luis Insua, Joana Sa Pessoa, Donna M Small

J Control Release· June 2018

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Inhibition of ataxia telangiectasia related-3 (ATR) improves therapeutic index in preclinical models of non-small cell lung cancer (NSCLC) radiotherapy.
Victoria Dunne, Mihaela Ghita, Donna M Small, Caroline B M Coffey, Sinead Weldon

Radiother Oncol· September 2017

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Characterisation of eppin function: expression and activity in the lung.
Aaron Scott, Arlene Glasgow, Donna Small, Simon Carlile, Maelíosa McCrudden

Eur Respir J· July 2017

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The role of whey acidic protein four-disulfide-core proteins in respiratory health and disease.
Donna M Small, Declan F Doherty, Caoifa M Dougan, Sinéad Weldon, Clifford C Taggart

Biol Chem· April 2017

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Innate Lymphoid Cells Are the Predominant Source of IL-17A during the Early Pathogenesis of Acute Respiratory Distress Syndrome.
Roshell Muir, Megan Osbourn, Alice V Dubois, Emma Doran, Donna M Small

Am J Respir Crit Care Med· February 2016

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CCL2 is transcriptionally controlled by the lysosomal protease cathepsin S in a CD74-dependent manner.
Richard D A Wilkinson, Sinead M Magorrian, Rich Williams, Andrew Young, Donna M Small

Oncotarget· October 2015

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Targeting Siglecs with a sialic acid-decorated nanoparticle abrogates inflammation.
Shaun Spence, Michelle K Greene, François Fay, Emily Hams, Sean P Saunders, Donna M Small

Sci Transl Med· September 2015

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A role for whey acidic protein four-disulfide-core 12 (WFDC12) in the regulation of the inflammatory response in the lung.
Arlene M A Glasgow, Donna M Small, Aaron Scott, Denise T McLean, Nicolas Camper

Thorax· May 2015

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A functional variant of elafin with improved anti-inflammatory activity for pulmonary inflammation.
Donna M Small, Marie-Louise Zani, Derek J Quinn, Sandrine Dallet-Choisy, Arlene M A Glasgow

Mol Ther· January 2015

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Efficient drug delivery and induction of apoptosis in colorectal tumors using a death receptor 5-targeted nanomedicine.
Daniela Schmid, Francois Fay, Donna M Small, Jakub Jaworski, Joel S Riley

Mol Ther· December 2014

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Cathepsin S from both tumor and tumor-associated cells promote cancer growth and neovascularization.
Donna M Small, Roberta E Burden, Jakub Jaworski, Shauna M Hegarty, Shaun Spence

Int J Cancer· November 2013

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Conatumumab (AMG 655) coated nanoparticles for targeted pro-apoptotic drug delivery.
Francois Fay, Kirsty M McLaughlin, Donna M Small, Dean A Fennell, Patrick G Johnston

Biomaterials· November 2011

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Antibody targeting of cathepsin S inhibits angiogenesis and synergistically enhances anti-VEGF.
Claire Ward, Diana Kuehn, Roberta E Burden, Julie A Gormley, Thomas J Jaquin, Donna Small

PLoS One· September 2010

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Antibody-mediated inhibition of cathepsin S blocks colorectal tumor invasion and angiogenesis.
Roberta E Burden, Julie A Gormley, Thomas J Jaquin, Donna M Small, Derek J Quinn

Clin Cancer Res· October 2009

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Proving that "less is more": the emergency department at Florida's North Broward Medical Center reduces minor care turnaround time.
Donna Small, Phil Ragusa, Boris Kalitenko, Jane Neubauer

J Emerg Nurs· June 2006

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