Publications by authors named "Doreen Chan"

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Safety and efficacy of once-weekly efruxifermin versus placebo in metabolic dysfunction-associated steatohepatitis (HARMONY): 96-week results from a multicentre, randomised, double-blind, placebo-controlled, phase 2b trial.
Mazen Noureddin, Juan P Frias, Guy W Neff, K Jean Lucas, Cynthia Behling, Doreen Chan

Lancet· August 2025

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Efruxifermin in Compensated Liver Cirrhosis Caused by MASH.
Mazen Noureddin, Mary E Rinella, Naga P Chalasani, Guy W Neff, K Jean Lucas, Doreen C Chan

N Engl J Med· June 2025

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Safety and Efficacy of Efruxifermin in Combination With a GLP-1 Receptor Agonist in Patients With NASH/MASH and Type 2 Diabetes in a Randomized Phase 2 Study.
Stephen A Harrison, Juan P Frias, K Jean Lucas, Gary Reiss, Guy Neff, Doreen Chan

Clin Gastroenterol Hepatol· January 2025

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Safety and efficacy of once-weekly efruxifermin versus placebo in non-alcoholic steatohepatitis (HARMONY): a multicentre, randomised, double-blind, placebo-controlled, phase 2b trial.
Stephen A Harrison, Juan P Frias, Guy Neff, Gary A Abrams, K Jean Lucas, Doreen Chan

Lancet Gastroenterol Hepatol· December 2023

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Polyacrylamide-based hydrogel coatings improve biocompatibility of implanted pump devices.
Doreen Chan, Caitlin L Maikawa, Andrea I d'Aquino, Shyam S Raghavan, Megan L Troxell

J Biomed Mater Res A· July 2023

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Angiogenic stem cell delivery platform to augment post-infarction neovasculature and reverse ventricular remodeling.
Hye Sook Shin, Akshara Thakore, Yuko Tada, Albert J Pedroza, Gentaro Ikeda, Doreen Chan

Sci Rep· October 2022

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Combinatorial Polyacrylamide Hydrogels for Preventing Biofouling on Implantable Biosensors.
Doreen Chan, Jun-Chau Chien, Eneko Axpe, Louis Blankemeier, Samuel W Baker

Adv Mater· June 2022

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Translational Applications of Hydrogels.
Santiago Correa, Abigail K Grosskopf, Hector Lopez Hernandez, Doreen Chan, Anthony C Yu

Chem Rev· September 2021

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Full closed loop open-source algorithm performance comparison in pigs with diabetes.
Rayhan A Lal, Caitlin L Maikawa, Dana Lewis, Sam W Baker, Anton A A Smith, Doreen Chan

Clin Transl Med· April 2021

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An ultrafast insulin formulation enabled by high-throughput screening of engineered polymeric excipients.
Joseph L Mann, Caitlin L Maikawa, Anton A A Smith, Abigail K Grosskopf, Sam W Baker, Doreen Chan

Sci Transl Med· July 2020

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A co-formulation of supramolecularly stabilized insulin and pramlintide enhances mealtime glucagon suppression in diabetic pigs.
Caitlin L Maikawa, Anton A A Smith, Lei Zou, Gillie A Roth, Emily C Gale, Doreen Chan

Nat Biomed Eng· May 2020

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A human mission to Mars: Predicting the bone mineral density loss of astronauts.
Eneko Axpe, Doreen Chan, Metadel F Abegaz, Ann-Sofie Schreurs, Joshua S Alwood

PLoS One· April 2020

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Wildfire prevention through prophylactic treatment of high-risk landscapes using viscoelastic retardant fluids.
Anthony C Yu, Hector Lopez Hernandez, Andrew H Kim, Lyndsay M Stapleton, Reuben J Brand, Doreen Chan

Proc Natl Acad Sci U S A· October 2019

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A Multiscale Model for Solute Diffusion in Hydrogels.
Eneko Axpe, Doreen Chan, Giovanni S Offeddu, Yin Chang, David Merida

Macromolecules· September 2019

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A Biocompatible Therapeutic Catheter-Deliverable Hydrogel for In Situ Tissue Engineering.
Amanda N Steele, Lyndsay M Stapleton, Justin M Farry, Haley J Lucian, Michael J Paulsen, Doreen Chan

Adv Healthc Mater· March 2019

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Engineering the Mechanical Properties of Polymer Networks with Precise Doping of Primary Defects.
Doreen Chan, Yichuan Ding, Reinhold H Dauskardt, Eric A Appel

ACS Appl Mater Interfaces· December 2017

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Single-Chain Polymeric Nanocarriers: A Platform for Determining Structure-Function Correlations in the Delivery of Molecular Cargo.
Doreen Chan, Anthony C Yu, Eric A Appel

Biomacromolecules· April 2017

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Scalable manufacturing of biomimetic moldable hydrogels for industrial applications.
Anthony C Yu, Haoxuan Chen, Doreen Chan, Gillie Agmon, Lyndsay M Stapleton

Proc Natl Acad Sci U S A· December 2016

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Craniofacial profile in Southern Chinese with hypodontia.
Doreen W S Chan, Nabil Samman, Anne S McMillan

Eur J Orthod· June 2009

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