Publications by authors named "Doris Rau"

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Toward generalizable prediction of antibody thermostability using machine learning on sequence and structure features.
Ameya Harmalkar, Roshan Rao, Yuxuan Richard Xie, Jonas Honer, Wibke Deisting, Doris Rau

MAbs· January 2023

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The PSMA-targeting Half-life Extended BiTE Therapy AMG 160 has Potent Antitumor Activity in Preclinical Models of Metastatic Castration-resistant Prostate Cancer.
Petra Deegen, Oliver Thomas, Olivier Nolan-Stevaux, Shyun Li, Joachim Wahl, Doris Rau, Tobias Raum

Clin Cancer Res· May 2021

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Regression of human prostate cancer xenografts in mice by AMG 212/BAY2010112, a novel PSMA/CD3-Bispecific BiTE antibody cross-reactive with non-human primate antigens.
Matthias Friedrich, Tobias Raum, Ralf Lutterbuese, Markus Voelkel, Petra Deegen, Doris Rau

Mol Cancer Ther· December 2012

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Side-by-side analysis of five clinically tested anti-EpCAM monoclonal antibodies.
Markus Münz, Alexander Murr, Majk Kvesic, Doris Rau, Susanne Mangold, Tobias Raum

Cancer Cell Int· November 2010

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T cell-engaging BiTE antibodies specific for EGFR potently eliminate KRAS- and BRAF-mutated colorectal cancer cells.
Ralf Lutterbuese, Tobias Raum, Roman Kischel, Patrick Hoffmann, Susanne Mangold, Doris Rau

Proc Natl Acad Sci U S A· July 2010

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Human IgG1 antibodies antagonizing activating receptor NKG2D on natural killer cells.
Jutta Steigerwald, Tobias Raum, Stefan Pflanz, Ronny Cierpka, Susanne Mangold, Doris Rau

MAbs· March 2010

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Antitumor activity of an EpCAM/CD3-bispecific BiTE antibody during long-term treatment of mice in the absence of T-cell anergy and sustained cytokine release.
Maria Amann, Sandrine D'Argouges, Grit Lorenczewski, Klaus Brischwein, Roman Kischel, Doris Rau, Tobias Raum

J Immunother· June 2009

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Potent control of tumor growth by CEA/CD3-bispecific single-chain antibody constructs that are not competitively inhibited by soluble CEA.
Ralf Lutterbuese, Tobias Raum, Roman Kischel, Petra Lutterbuese, Bernd Schlereth, Doris Rau

J Immunother· May 2009

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CD19-/CD3-bispecific antibody of the BiTE class is far superior to tandem diabody with respect to redirected tumor cell lysis.
Michael Mølhøj, Sandrine Crommer, Klaus Brischwein, Doris Rau, Mirnaalini Sriskandarajah

Mol Immunol· March 2007

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Single-chain Fv antibody-alkaline phosphatase fusion proteins produced by one-step cloning as rapid detection tools for ELISA.
Doris Rau, Karl Kramer, Bertold Hock

J Immunoassay Immunochem· November 2002

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Cloning, functional expression and kinetic characterization of pesticide-selective Fab fragment variants derived by molecular evolution of variable antibody genes.
Doris Rau, Karl Kramer, Bertold Hock

Anal Bioanal Chem· January 2002

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