Publications by authors named "Dorothy Cheung"

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Safety, Pharmacokinetics, and Immunogenicity of Astegolimab, an Anti-ST2 Monoclonal Antibody, in Randomized, Phase I Clinical Studies.
Wenhui Zhang, Dorothy Cheung, Alice Fong, Logan Brooks, Michele A Grimbaldeston

Clin Transl Sci· October 2025

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Rapidly Progressing Melioidosis Outbreak in City Center Zoo, Hong Kong, 2024.
Christopher J Brackman, Ivan Tak-Fai Wong, Allen S L Chan, Patrick C K Pun, Dorothy Hong-Ting Cheung

Emerg Infect Dis· September 2025

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Practical media formulations for rapid growth of and other vaginal bacteria.
Daniella Serrador, Jhenielle R Campbell, Landon J Getz, Dorothy Cheung, Gelila Shefraw

Appl Environ Microbiol· August 2025

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The effectiveness of video-based exercise training program for people with intellectual disability: a multicenter study.
Rachel Kwan, Grace Szeto, Ester Ho, Annie Wu, Lavinia Wong, Dorothy Cheung

Front Sports Act Living· May 2024

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Weak to no correlation between quantitative high-resolution computed tomography metrics and lung function change in fibrotic diseases.
Yixuan Zou, Xuefeng Hou, Neha Anegondi, Mohammadreza Negahdar, Dorothy Cheung

ERJ Open Res· September 2023

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Astegolimab or Efmarodocokin Alfa in Patients With Severe COVID-19 Pneumonia: A Randomized, Phase 2 Trial.
Michael Waters, James A McKinnell, Andre C Kalil, Greg S Martin, Timothy G Buchman, Dorothy Cheung

Crit Care Med· January 2023

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Phase 2 randomized clinical trial of astegolimab in patients with moderate to severe atopic dermatitis.
Marcus Maurer, Dorothy S Cheung, Wiebke Theess, Xiaoying Yang, Michael Dolton

J Allergy Clin Immunol· December 2022

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Population Pharmacokinetics and Exposure-Response Relationships of Astegolimab in Patients With Severe Asthma.
Naoki Kotani, Michael Dolton, Robin J Svensson, Jakob Ribbing, Lena E Friberg, Dorothy Cheung

J Clin Pharmacol· July 2022

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Astegolimab, an anti-ST2, in chronic obstructive pulmonary disease (COPD-ST2OP): a phase 2a, placebo-controlled trial.
Ahmed J Yousuf, Seid Mohammed, Liesl Carr, Mohammadali Yavari Ramsheh, Claudia Micieli, Dorothy Cheung

Lancet Respir Med· May 2022

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A whole genome sequencing study of moderate to severe asthma identifies a lung function locus associated with asthma risk.
Diana Chang, Julie Hunkapiller, Tushar Bhangale, Jens Reeder, Kiran Mukhyala, Dorothy S Cheung

Sci Rep· April 2022

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Population repeated time-to-event analysis of exacerbations in asthma patients: A novel approach for predicting asthma exacerbations based on biomarkers, spirometry, and diaries/questionnaires.
Robin J Svensson, Jakob Ribbing, Naoki Kotani, Michael Dolton, Shweta Vadhavkar, Dorothy Cheung

CPT Pharmacometrics Syst Pharmacol· October 2021

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Rates of Major Cardiovascular Events in Severe Asthma: U.S. Real-World and Clinical Trial-Eligible Populations.
Parul Dayal, Carlos Iribarren, Dorothy Cheung, Michael E Rothenberg, C Victor Spain

Ann Am Thorac Soc· September 2021

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Astegolimab (anti-ST2) efficacy and safety in adults with severe asthma: A randomized clinical trial.
Steven G Kelsen, Ioana O Agache, Weily Soong, Elliot Israel, Geoffrey L Chupp, Dorothy S Cheung

J Allergy Clin Immunol· September 2021

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A phase 1, randomized study to evaluate safety, tolerability, and pharmacokinetics of GDC-3280, a potential novel anti-fibrotic small molecule, in healthy subjects.
Dorothy Cheung, Alice Fong, Han Ting Ding, Christopher R Cabanski, Jianshuang Wang

Pulm Pharmacol Ther· August 2021

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Epigenomic programming in early fetal brain development.
Luolan Li, Cecile L Maire, Misha Bilenky, Annaïck Carles, Alireza Heravi-Moussavi, Dorothy Cheung

Epigenomics· June 2020

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Determination of a novel antifibrotic small molecule GDC-3280 in human plasma and urine by liquid chromatography tandem mass spectrometry to support its first-in-human clinical trial.
Jianshuang Wang, Michael Van Parys, Lin Pan, Yuan Chen, Dorothy Cheung

Biomed Chromatogr· April 2019

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Cysteinyl leukotriene receptor 1 expression identifies a subset of neutrophils during the antiviral response that contributes to postviral atopic airway disease.
Dorothy S Cheung, Jerome A Sigua, Pippa M Simpson, Ke Yan, Syed-Rehan A Hussain

J Allergy Clin Immunol· October 2018

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Intestinal Microbiota Disruption Reduces Regulatory T Cells and Increases Respiratory Viral Infection Mortality Through Increased IFNγ Production.
Mitchell H Grayson, Lauren E Camarda, Syed-Rehan A Hussain, Sarah J Zemple, Michael Hayward, Dorothy S Cheung

Front Immunol· July 2018

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The Genome of the Beluga Whale (Delphinapterus leucas).
Steven J M Jones, Gregory A Taylor, Simon Chan, René L Warren, S Austin Hammond, Dorothy Cheung

Genes (Basel)· December 2017

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A survivor: the eosinophil as a regulator in asthma.
Dorothy S Cheung, Mitchell H Grayson

J Allergy Clin Immunol· February 2015

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Epigenetic and transcriptional determinants of the human breast.
Philippe Gascard, Misha Bilenky, Mahvash Sigaroudinia, Jianxin Zhao, Luolan Li, Dorothy Cheung

Nat Commun· February 2015

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CD49d-expressing neutrophils differentiate atopic from nonatopic individuals.
Jerome A Sigua, Becky Buelow, Dorothy S Cheung, Erika Buell, Desire Hunter

J Allergy Clin Immunol· March 2014

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Role of viruses in the development of atopic disease in pediatric patients.
Dorothy S Cheung, Mitchell H Grayson

Curr Allergy Asthma Rep· December 2012

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Expression of high-affinity IgE receptor on human peripheral blood dendritic cells in children.
Monica Vasudev, Dorothy S Cheung, Hannah Pincsak, Shun-Hwa Li, Ke Yan

PLoS One· August 2012

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Development of atopy by severe paramyxoviral infection in a mouse model.
Dorothy S Cheung, Sarah J Ehlenbach, Tom Kitchens, Desire A Riley, Mitchell H Grayson

Ann Allergy Asthma Immunol· December 2010

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