Publications by authors named "Drew Deniger"

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Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade.
Douglas C Palmer, Beau R Webber, Yogin Patel, Matthew J Johnson, Christine M Kariya, Drew C Deniger

Med· October 2022

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Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor-Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors.
Sanghyun P Kim, Nolan R Vale, Nikolaos Zacharakis, Sri Krishna, Zhiya Yu, Drew C Deniger

Cancer Immunol Res· August 2022

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Cancer genes disfavoring T cell immunity identified via integrated systems approach.
Rigel J Kishton, Shashank J Patel, Amy E Decker, Suman K Vodnala, Maggie Cam, Drew C Deniger

Cell Rep· August 2022

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Rapid Identification and Evaluation of Neoantigen-reactive T-Cell Receptors From Single Cells.
Biman C Paria, Noam Levin, Frank J Lowery, Anna Pasetto, Drew C Deniger

J Immunother· January 2021

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Antigen Experienced T Cells from Peripheral Blood Recognize p53 Neoantigens.
Parisa Malekzadeh, Rami Yossef, Gal Cafri, Biman C Paria, Frank J Lowery, Drew C Deniger

Clin Cancer Res· March 2020

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Unique Neoantigens Arise from Somatic Mutations in Patients with Gastrointestinal Cancers.
Maria R Parkhurst, Paul F Robbins, Eric Tran, Todd D Prickett, Jared J Gartner, Drew C Deniger

Cancer Discov· August 2019

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Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal Cancer.
Winifred Lo, Maria Parkhurst, Paul F Robbins, Eric Tran, Yong-Chen Lu, Drew Deniger

Cancer Immunol Res· April 2019

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Neoantigen screening identifies broad TP53 mutant immunogenicity in patients with epithelial cancers.
Parisa Malekzadeh, Anna Pasetto, Paul F Robbins, Maria R Parkhurst, Biman C Paria, Drew C Deniger

J Clin Invest· March 2019

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Tumor-infiltrating human CD4 regulatory T cells display a distinct TCR repertoire and exhibit tumor and neoantigen reactivity.
Mojgan Ahmadzadeh, Anna Pasetto, Li Jia, Drew C Deniger, Sanja Stevanović

Sci Immunol· January 2019

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Memory T cells targeting oncogenic mutations detected in peripheral blood of epithelial cancer patients.
Gal Cafri, Rami Yossef, Anna Pasetto, Drew C Deniger, Yong-Chen Lu

Nat Commun· January 2019

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T-cell Responses to "Hotspot" Mutations and Unique Neoantigens Expressed by Human Ovarian Cancers.
Drew C Deniger, Anna Pasetto, Paul F Robbins, Jared J Gartner, Todd D Prickett

Clin Cancer Res· November 2018

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Enhanced detection of neoantigen-reactive T cells targeting unique and shared oncogenes for personalized cancer immunotherapy.
Rami Yossef, Eric Tran, Drew C Deniger, Alena Gros, Anna Pasetto

JCI Insight· October 2018

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Redirecting Specificity of T cells Using the Sleeping Beauty System to Express Chimeric Antigen Receptors by Mix-and-Matching of VL and VH Domains Targeting CD123+ Tumors.
Radhika Thokala, Simon Olivares, Tiejuan Mi, Sourindra Maiti, Drew Deniger

PLoS One· July 2017

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A Pilot Trial of the Combination of Vemurafenib with Adoptive Cell Therapy in Patients with Metastatic Melanoma.
Drew C Deniger, Mei Li M Kwong, Anna Pasetto, Mark E Dudley, John R Wunderlich

Clin Cancer Res· January 2017

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Tumor- and Neoantigen-Reactive T-cell Receptors Can Be Identified Based on Their Frequency in Fresh Tumor.
Anna Pasetto, Alena Gros, Paul F Robbins, Drew C Deniger, Todd D Prickett

Cancer Immunol Res· September 2016

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Stable, Nonviral Expression of Mutated Tumor Neoantigen-specific T-cell Receptors Using the Sleeping Beauty Transposon/Transposase System.
Drew C Deniger, Anna Pasetto, Eric Tran, Maria R Parkhurst, Cyrille J Cohen

Mol Ther· June 2016

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Sleeping Beauty Transposition of Chimeric Antigen Receptors Targeting Receptor Tyrosine Kinase-Like Orphan Receptor-1 (ROR1) into Diverse Memory T-Cell Populations.
Drew C Deniger, Jianqiang Yu, M Helen Huls, Matthew J Figliola, Tiejuan Mi

PLoS One· April 2016

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Clinical applications of gamma delta T cells with multivalent immunity.
Drew C Deniger, Judy S Moyes, Laurence J N Cooper

Front Immunol· January 2015

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Activating and propagating polyclonal gamma delta T cells with broad specificity for malignancies.
Drew C Deniger, Sourindra N Maiti, Tiejuan Mi, Kirsten C Switzer, Vijaya Ramachandran

Clin Cancer Res· November 2014

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Bispecific T-cells expressing polyclonal repertoire of endogenous γδ T-cell receptors and introduced CD19-specific chimeric antigen receptor.
Drew C Deniger, Kirsten Switzer, Tiejuan Mi, Sourindra Maiti, Lenka Hurton

Mol Ther· March 2013

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Small interfering RNA profiling reveals key role of clathrin-mediated endocytosis and early endosome formation for infection by respiratory syncytial virus.
Andrey A Kolokoltsov, Drew Deniger, Elisa H Fleming, Norbert J Roberts, Jon M Karpilow

J Virol· July 2007

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Targeting and penetration of virus receptor bearing cells by nanoparticles coated with envelope proteins of Moloney murine leukemia virus.
Drew C Deniger, Andrey A Kolokoltsov, Andrew C Moore, Thomas B Albrecht, Robert A Davey

Nano Lett· November 2006

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