Publications by authors named "Duane D Miller"

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Anti-mitotic agent SB-216 overcomes taxane resistance in castration-resistant prostate cancer and exhibits anti-tumour efficacy in pancreatic cancer.
Rui Wang, Chun Cai, Shanshan Deng, Yang Xie, Satyanarayana Pochampally, Duane D Miller

Br J Pharmacol· December 2025

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Design and synthesis of novel 4-aryl-2-benzoyl-imidazoles as colchicine binding site inhibitors.
Najah Albadari, Yang Xie, Qinghui Wang, Darcie J Miller, Judith Quadrozzi Gruntz, Duane D Miller

Eur J Med Chem· November 2025

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Discovery of potent and brain-penetrable tubulin inhibitors that effectively suppress breast cancer brain metastasis.
Raisa I Krutilina, Kelli L Adeleye, Hilaire C Playa, Satyanarayana Pochampally, Souvik Banjeree, Duane D Miller

Mol Cancer Ther· November 2025

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Corrigendum to "Advances in the understanding of androgen receptor structure and function and in the development of next-generation AR-targeted therapeutics". [Steroids 210 (2024) 109486].
Wendy Effah, Marjana Khalil, Dong-Jin Hwang, Duane D Miller, Ramesh Narayanan

Steroids· September 2025

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Modulation of occludin, NF-κB, p-STAT3, and Th17 response by DJ-X-025 decreases inflammation and ameliorates experimental colitis.
Mousumi Mandal, Md Abdullah Al Mamun, Ahmed Rakib, Santosh Kumar, Frank Park, Duane D Miller

Biomed Pharmacother· April 2025

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Structural Activity Relationship Analysis of New Diphenyl PFI-3 Analogues Targeting for the Treatment of Glioblastoma.
Dong-Jin Hwang, Chuanhe Yang, Yinan Wang, Hannah Kelso, Satyanarayana Pochampally, Duane D Miller

Pharmaceuticals (Basel)· April 2025

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Tyr1497 in the BRG1 Bromodomain of the SWI/SNF Complex is Critical for the Binding and Function of a Selective BRG1 Inhibitor.
Yinan Wang, Chuanhe Yang, Gustavo A Miranda-Carboni, Hannah Kelso, Jayaraman Seetharaman, Duane D Miller

J Cell Mol Med· March 2025

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Discovery of a potent and selective TRPC3 antagonist with neuroprotective effects.
Jiaxing Wang, Sicheng Zhang, Vijay K Boda, Hao Chen, Hyunseo Park, Duane D Miller

Bioorg Med Chem· January 2025

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VERU-111, an orally available tubulin inhibitor, suppresses ovarian tumor growth and metastasis.
Shelby Waddell, Guannan Zhao, Ziping Liu, Hao Chen, Wenjing Zhang, Duane D Miller

J Pharmacol Exp Ther· January 2025

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Advances in the understanding of androgen receptor structure and function and in the development of next-generation AR-targeted therapeutics.
Wendy Effah, Marjana Khalil, Dong-Jin Hwang, Duane D Miller, Ramesh Narayanan

Steroids· October 2024

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DJ-X-013 reduces LPS-induced inflammation, modulates Th17/ myeloid-derived suppressor cells, and alters NF-κB expression to ameliorate experimental colitis.
Mousumi Mandal, Ahmed Rakib, Md Abdullah Al Mamun, Santosh Kumar, Frank Park, Duane D Miller

Biomed Pharmacother· October 2024

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A molecular switch from tumor suppressor to oncogene in ER+ve breast cancer: Role of androgen receptor, JAK-STAT, and lineage plasticity.
Sarah Asemota, Wendy Effah, Jeremiah Holt, Daniel Johnson, Linnea Cripe, Duane D Miller

Proc Natl Acad Sci U S A· October 2024

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Biological activity of a stable 6-aryl-2-benzoyl-pyridine colchicine-binding site inhibitor, 60c, in metastatic, triple-negative breast cancer.
Damilola Oluwalana, Kelli L Adeleye, Raisa I Krutilina, Hao Chen, Hilaire Playa, Duane D Miller

Cancer Lett· August 2024

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Identification of a targetable JAK-STAT enriched androgen receptor and androgen receptor splice variant positive triple-negative breast cancer subtype.
Sarah Asemota, Wendy Effah, Kirsten L Young, Jeremiah Holt, Linnea Cripe, Duane D Miller

Cell Rep· December 2023

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Next-generation bromodomain inhibitors of the SWI/SNF complex enhance DNA damage and cell death in glioblastoma.
Chuanhe Yang, Yali He, Yinan Wang, Peter J McKinnon, Vijay Shahani, Duane D Miller

J Cell Mol Med· September 2023

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Design, Synthesis, and Biological Evaluation of Pyrimidine Dihydroquinoxalinone Derivatives as Tubulin Colchicine Site-Binding Agents That Displayed Potent Anticancer Activity Both In Vitro and In Vivo.
Satyanarayana Pochampally, Kelli L Hartman, Rui Wang, Jiaxing Wang, Mi-Kyung Yun, Duane D Miller

ACS Pharmacol Transl Sci· April 2023

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Metabolism-Guided Selective Androgen Receptor Antagonists: Design, Synthesis, and Biological Evaluation for Activity against Enzalutamide-Resistant Prostate Cancer.
Dong-Jin Hwang, Yali He, Suriyan Ponnusamy, Thirumagal Thiyagarajan, Michael L Mohler, Duane D Miller

J Med Chem· March 2023

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SB226, an inhibitor of tubulin polymerization, inhibits paclitaxel-resistant melanoma growth and spontaneous metastasis.
Shanshan Deng, Souvik Banerjee, Hao Chen, Satyanarayana Pochampally, Yuxi Wang, Duane D Miller

Cancer Lett· February 2023

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Inhibiting androgen receptor splice variants with cysteine-selective irreversible covalent inhibitors to treat prostate cancer.
Thirumagal Thiyagarajan, Suriyan Ponnusamy, Dong-Jin Hwang, Yali He, Sarah Asemota, Duane D Miller

Proc Natl Acad Sci U S A· January 2023

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Sabizabulin, a Potent Orally Bioavailable Colchicine Binding Site Agent, Suppresses HER2+ Breast Cancer and Metastasis.
Raisa I Krutilina, Kelli L Hartman, Damilola Oluwalana, Hilaire C Playa, Deanna N Parke, Duane D Miller

Cancers (Basel)· October 2022

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Colchicine-Binding Site Agent CH-2-77 as a Potent Tubulin Inhibitor Suppressing Triple-Negative Breast Cancer.
Shanshan Deng, Raisa I Krutilina, Kelli L Hartman, Hao Chen, Deanna N Parke, Duane D Miller

Mol Cancer Ther· July 2022

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Molecular interactions at the colchicine binding site in tubulin: An X-ray crystallography perspective.
Jiaxing Wang, Duane D Miller, Wei Li

Drug Discov Today· March 2022

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Novel structural-related analogs of PFI-3 (SRAPs) that target the BRG1 catalytic subunit of the SWI/SNF complex increase the activity of temozolomide in glioblastoma cells.
Yali He, Chuanhe Yang, Yinan Wang, Joshua R Sacher, Michelle M Sims, Duane D Miller

Bioorg Med Chem· January 2022

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Modulation by 17,20S(OH)pD of Fibrosis-Related Mediators in Dermal Fibroblast Lines from Healthy Donors and from Patients with Systemic Sclerosis.
Monica L Brown Lobbins, Andrzej T Slominski, Karen A Hasty, Sicheng Zhang, Duane D Miller

Int J Mol Sci· December 2021

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Drug Repurposing to Identify Nilotinib as a Potential SARS-CoV-2 Main Protease Inhibitor: Insights from a Computational and Study.
Souvik Banerjee, Shalini Yadav, Sourav Banerjee, Sayo O Fakayode, Jyothi Parvathareddy, Duane D Miller

J Chem Inf Model· November 2021

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