Publications by authors named "Duane H Hamilton"

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Combination Therapy Approaches to Enhance the Efficacy of ERV-Targeting Vaccines in Cancer.
Maria Gracia-Hernandez, Maria Del Mar Maldonado, Jeffrey Schlom, Duane H Hamilton

Cancer Immunol Res· June 2025

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Combination of a therapeutic cancer vaccine targeting the endogenous retroviral envelope protein ERVMER34-1 with immune-oncology agents facilitates expansion of neoepitope-specific T cells and promotes tumor control.
Maria Del Mar Maldonado, Maria Gracia-Hernandez, Loc Huu Le, Masafumi Iida, James L Gulley, Duane H Hamilton

J Immunother Cancer· May 2025

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Hypothesis: the generation of T cells directed against neoepitopes employing immune-mediating agents other than neoepitope vaccines.
Jeffrey Schlom, Renee N Donahue, Claudia Palena, Sofia R Gameiro, James W Hodge, Duane H Hamilton

J Immunother Cancer· July 2024

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Blockade of tumor-derived colony-stimulating factor 1 (CSF1) promotes an immune-permissive tumor microenvironment.
Maria Del Mar Maldonado, Jeffrey Schlom, Duane H Hamilton

Cancer Immunol Immunother· October 2023

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Fulvestrant increases the susceptibility of enzalutamide-resistant prostate cancer cells to NK-mediated lysis.
Madeline Dahut, Kristen Fousek, Lucas A Horn, Shantel Angstadt, Haiyan Qin, Duane H Hamilton

J Immunother Cancer· September 2023

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Exploiting docetaxel-induced tumor cell necrosis with tumor targeted delivery of IL-12.
S Elizabeth Franks, Ginette S Santiago-Sanchez, Kellsye P Fabian, Kristen Solocinski, Paul L Chariou, Duane H Hamilton

Cancer Immunol Immunother· August 2023

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An Interleukin-15 Superagonist Enables Antitumor Efficacy of Natural Killer Cells Against All Molecular Variants of SCLC.
Kristen Fousek, Lucas A Horn, Haiyan Qin, Madeline Dahut, Masafumi Iida, Duane H Hamilton

J Thorac Oncol· March 2023

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Identification and validation of expressed HLA-binding breast cancer neoepitopes for potential use in individualized cancer therapy.
Hannah Reimann, Andrew Nguyen, J Zachary Sanborn, Charles J Vaske, Stephen C Benz, Duane H Hamilton

J Immunother Cancer· June 2021

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Combination therapies utilizing neoepitope-targeted vaccines.
Karin L Lee, Jeffrey Schlom, Duane H Hamilton

Cancer Immunol Immunother· April 2021

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Vaccine Increases the Diversity and Activation of Intratumoral T Cells in the Context of Combination Immunotherapy.
Lucas A Horn, Kristen Fousek, Duane H Hamilton, James W Hodge, John A Zebala

Cancers (Basel)· February 2021

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Simultaneous inhibition of CXCR1/2, TGF-β, and PD-L1 remodels the tumor and its microenvironment to drive antitumor immunity.
Lucas A Horn, Jeffrey Riskin, Heidi A Hempel, Kristen Fousek, Hanne Lind, Duane H Hamilton

J Immunother Cancer· March 2020

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Cooperative Immune-Mediated Mechanisms of the HDAC Inhibitor Entinostat, an IL15 Superagonist, and a Cancer Vaccine Effectively Synergize as a Novel Cancer Therapy.
Kristin C Hicks, Karin M Knudson, Karin L Lee, Duane H Hamilton, James W Hodge

Clin Cancer Res· February 2020

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Efficient Tumor Clearance and Diversified Immunity through Neoepitope Vaccines and Combinatorial Immunotherapy.
Karin L Lee, Stephen C Benz, Kristin C Hicks, Andrew Nguyen, Sofia R Gameiro, Duane H Hamilton

Cancer Immunol Res· August 2019

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Loss of the Cyclin-Dependent Kinase Inhibitor 1 in the Context of Brachyury-Mediated Phenotypic Plasticity Drives Tumor Resistance to Immune Attack.
Duane H Hamilton, Kristen K McCampbell, Claudia Palena

Front Oncol· May 2018

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Phase I Study of a Poxviral TRICOM-Based Vaccine Directed Against the Transcription Factor Brachyury.
Christopher R Heery, Claudia Palena, Sheri McMahon, Renee N Donahue, Lauren M Lepone, Duane H Hamilton

Clin Cancer Res· November 2017

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Brachyury-YAP Regulatory Axis Drives Stemness and Growth in Cancer.
Sagar R Shah, Justin M David, Nathaniel D Tippens, Ahmed Mohyeldin, Juan C Martinez-Gutierrez, Duane H Hamilton

Cell Rep· October 2017

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Development of Cancer Vaccines Targeting Brachyury, a Transcription Factor Associated with Tumor Epithelial-Mesenchymal Transition.
Duane H Hamilton, Justin M David, Charli Dominguez, Claudia Palena

Cells Tissues Organs· May 2017

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Targeting Estrogen Receptor Signaling with Fulvestrant Enhances Immune and Chemotherapy-Mediated Cytotoxicity of Human Lung Cancer.
Duane H Hamilton, Lesley Mathews Griner, Jonathan M Keller, Xin Hu, Noel Southall

Clin Cancer Res· December 2016

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Brachyury, a vaccine target, is overexpressed in triple-negative breast cancer.
Duane H Hamilton, Mario Roselli, Patrizia Ferroni, Leopoldo Costarelli, Francesco Cavaliere

Endocr Relat Cancer· October 2016

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IL-8 signaling is involved in resistance of lung carcinoma cells to erlotinib.
Romaine I Fernando, Duane H Hamilton, Charli Dominguez, Justin M David, Kristen K McCampbell

Oncotarget· July 2016

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The IL-8/IL-8R Axis: A Double Agent in Tumor Immune Resistance.
Justin M David, Charli Dominguez, Duane H Hamilton, Claudia Palena

Vaccines (Basel)· June 2016

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Immune Targeting of Tumor Epithelial-Mesenchymal Transition via Brachyury-Based Vaccines.
Claudia Palena, Duane H Hamilton

Adv Cancer Res· April 2016

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MUC1 upregulation promotes immune resistance in tumor cells undergoing brachyury-mediated epithelial-mesenchymal transition.
Justin M David, Duane H Hamilton, Claudia Palena

Oncoimmunology· April 2016

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Aberrant expression of the embryonic transcription factor brachyury in human tumors detected with a novel rabbit monoclonal antibody.
Duane H Hamilton, Romaine I Fernando, Jeffrey Schlom, Claudia Palena

Oncotarget· March 2015

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Overexpression of the EMT driver brachyury in breast carcinomas: association with poor prognosis.
Claudia Palena, Mario Roselli, Mary T Litzinger, Patrizia Ferroni, Leopoldo Costarelli, Duane H Hamilton

J Natl Cancer Inst· May 2014

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