Publications by authors named "Duncan Hay"

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Silicone Ankle Bands as a Tool to Assess Infant Exposures to Semivolatile Organic Chemicals in Indoor Environments.
Catherine F Wise, Elizabeth Boxer, Jillian Hurst, Rebecca M Hoehn, Nicholas J Herkert, Duncan Hay

Environ Sci Technol Lett· October 2025

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Optimisation of a novel series of ENaC inhibitors, leading to the selection of the long-acting inhaled clinical candidate ETD001, a potential new treatment for cystic fibrosis.
Henry Danahay, Martin Gosling, Roy Fox, Sarah Lilley, Holly Charlton, Duncan A Hay

Eur J Med Chem· January 2025

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Characterizing firefighter's exposure to over 130 SVOCs using silicone wristbands: A pilot study comparing on-duty and off-duty exposures.
Jessica L Levasseur, Kate Hoffman, Nicholas J Herkert, Ellen Cooper, Duncan Hay

Sci Total Environ· August 2022

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Monitoring Human Exposure to Organophosphate Esters: Comparing Silicone Wristbands with Spot Urine Samples as Predictors of Internal Dose.
Kate Hoffman, Jessica L Levasseur, Sharon Zhang, Duncan Hay, Nicholas J Herkert

Environ Sci Technol Lett· September 2021

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Structure-Based Design of Highly Selective Inhibitors of the CREB Binding Protein Bromodomain.
R Aldrin Denny, Andrew C Flick, Jotham Coe, Jonathan Langille, Arindrajit Basak, Duncan A Hay

J Med Chem· July 2017

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Chemical probes and inhibitors of bromodomains outside the BET family.
Moses Moustakim, Peter G K Clark, Duncan A Hay, Darren J Dixon, Paul E Brennan

Medchemcomm· December 2016

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Generation of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia Therapy.
Sarah Picaud, Oleg Fedorov, Angeliki Thanasopoulou, Katharina Leonards, Katherine Jones, Duncan Hay

Cancer Res· December 2015

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CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responses.
Ariane Hammitzsch, Cynthia Tallant, Oleg Fedorov, Alison O'Mahony, Paul E Brennan, Duncan A Hay

Proc Natl Acad Sci U S A· August 2015

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The discovery of potent nonstructural protein 5A (NS5A) inhibitors with a unique resistance profile-Part 1.
Thien Duc Tran, Florian Wakenhut, Chris Pickford, Stephen Shaw, Mike Westby, Duncan Hay

ChemMedChem· July 2014

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The discovery of potent nonstructural protein 5A (NS5A) inhibitors with a unique resistance profile-Part 2.
Florian Wakenhut, Thien Duc Tran, Chris Pickford, Stephen Shaw, Mike Westby, Duncan Hay

ChemMedChem· July 2014

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Discovery and optimization of small-molecule ligands for the CBP/p300 bromodomains.
Duncan A Hay, Oleg Fedorov, Sarah Martin, Dean C Singleton, Cynthia Tallant

J Am Chem Soc· July 2014

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A series of potent CREBBP bromodomain ligands reveals an induced-fit pocket stabilized by a cation-π interaction.
Timothy P C Rooney, Panagis Filippakopoulos, Oleg Fedorov, Sarah Picaud, Wilian A Cortopassi, Duncan A Hay

Angew Chem Int Ed Engl· June 2014

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Fish navigation of large dams emerges from their modulation of flow field experience.
R Andrew Goodwin, Marcela Politano, Justin W Garvin, John M Nestler, Duncan Hay

Proc Natl Acad Sci U S A· April 2014

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The design and synthesis of 5- and 6-isoxazolylbenzimidazoles as selective inhibitors of the BET bromodomains.
Duncan Hay, Oleg Fedorov, Panagis Filippakopoulos, Sarah Martin, Martin Philpott

Medchemcomm· January 2013

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Progress in the development and application of small molecule inhibitors of bromodomain-acetyl-lysine interactions.
David S Hewings, Timothy P C Rooney, Laura E Jennings, Duncan A Hay, Christopher J Schofield

J Med Chem· November 2012

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New lithium-zincate approaches for the selective functionalisation of pyrazine: direct dideprotozincation vs. nucleophilic alkylation.
Sharon E Baillie, Victoria L Blair, David C Blakemore, Duncan Hay, Alan R Kennedy

Chem Commun (Camb)· February 2012

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Synthesis of novel histamine H4 receptor antagonists.
Charlotte A L Lane, Duncan Hay, Charles E Mowbray, Michael Paradowski, Matthew D Selby

Bioorg Med Chem Lett· January 2012

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Discovery of a highly potent series of TLR7 agonists.
Peter Jones, David C Pryde, Thien-Duc Tran, Fiona M Adam, Gerwyn Bish, Duncan A Hay

Bioorg Med Chem Lett· October 2011

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Design and optimisation of orally active TLR7 agonists for the treatment of hepatitis C virus infection.
Thien-Duc Tran, David C Pryde, Peter Jones, Fiona M Adam, Neil Benson, Duncan A Hay

Bioorg Med Chem Lett· April 2011

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Discovery of a small molecule inhibitor through interference with the gp120-CD4 interaction.
David H Williams, Fiona Adam, David R Fenwick, Juin Fok-Seang, Iain Gardner, Duncan Hay

Bioorg Med Chem Lett· September 2009

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Design and optimisation of potent gp120-CD4 inhibitors.
Thien-Duc Tran, Fiona M Adam, Frederick Calo, David R Fenwick, Juin Fok-Seang, Duncan A Hay

Bioorg Med Chem Lett· September 2009

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Optimization of 5-aryloxyimidazole non-nucleoside reverse transcriptase inhibitors.
Lyn H Jones, Gill Allan, Romuald Corbau, Duncan Hay, Donald S Middleton

ChemMedChem· November 2008

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Cortisone in rheumatic carditis: some preliminary observations.
E N CHAMBERLAIN, J DUNCAN HAY, D M FREEMAN

Br Med J· May 1952

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