Publications by authors named "Earl Albone"

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A Novel Concept for Cleavable Linkers Applicable to Conjugation Chemistry - Design, Synthesis and Characterization.
Utpal Majumder, Xiaojie Zhu, Daniel Custar, Danyang Li, Hui Fang, Earl Albone

Chembiochem· February 2025

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Preclinical studies of BB-1701, a HER2-targeting eribulin-containing ADC with potent bystander effect and ICD activity.
Yang Wang, Bing Xia, Lixia Cao, Jianfeng Yang, Cui Feng, Earl Albone

Antib Ther· July 2024

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Antibody-drug conjugate MORAb-202 exhibits long-lasting antitumor efficacy in TNBC PDx models.
Keiji Furuuchi, Katherine Rybinski, James Fulmer, Tomoyuki Moriyama, Brian Drozdowski, Earl Albone

Cancer Sci· June 2021

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Efficient Production of Homogeneous Lysine-Based Antibody Conjugates Using Microbial Transglutaminase.
Jared L Spidel, Earl F Albone

Methods Mol Biol· April 2020

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Pre-clinical characterisation of E2814, a high-affinity antibody targeting the microtubule-binding repeat domain of tau for passive immunotherapy in Alzheimer's disease.
Malcolm Roberts, Ioanna Sevastou, Yoichi Imaizumi, Kavita Mistry, Sonia Talma, Earl Albone

Acta Neuropathol Commun· February 2020

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Specific loss of adipocyte CD248 improves metabolic health via reduced white adipose tissue hypoxia, fibrosis and inflammation.
Paul Petrus, Tara L Fernandez, Michelle M Kwon, Jenny L Huang, Victor Lei, Earl Albone

EBioMedicine· June 2019

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MORAb-202, an Antibody-Drug Conjugate Utilizing Humanized Anti-human FRα Farletuzumab and the Microtubule-targeting Agent Eribulin, has Potent Antitumor Activity.
Xin Cheng, Jing Li, Keigo Tanaka, Utpal Majumder, Andrew Z Milinichik, Earl F Albone

Mol Cancer Ther· December 2018

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Site-Specific Conjugation to Native and Engineered Lysines in Human Immunoglobulins by Microbial Transglutaminase.
Jared L Spidel, Benjamin Vaessen, Earl F Albone, Xin Cheng, Arielle Verdi

Bioconjug Chem· September 2017

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Tumor antigen CA125 suppresses antibody-dependent cellular cytotoxicity (ADCC) via direct antibody binding and suppressed Fc-γ receptor engagement.
James Bradford Kline, Rina P Kennedy, Earl Albone, Qimin Chao, Shawn Fernando

Oncotarget· August 2017

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Correlation of FCGRT genomic structure with serum immunoglobulin, albumin and farletuzumab pharmacokinetics in patients with first relapsed ovarian cancer.
Daniel J O'Shannessy, Katie Bendas, Charles Schweizer, Wenquan Wang, Earl Albone

Genomics· July 2017

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Generation of therapeutic immunoconjugates via Residue-Specific Conjugation Technology (RESPECT) utilizing a native cysteine in the light chain framework of Oryctolagus cuniculus.
Earl F Albone, Jared L Spidel, Xin Cheng, Young Chul Park, Sara Jacob

Cancer Biol Ther· May 2017

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Engineering humanized antibody framework sequences for optimal site-specific conjugation of cytotoxins.
Jared L Spidel, Earl F Albone, Xin Cheng, Benjamin Vaessen, Sara Jacob

MAbs· May 2017

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Novel antibody probes for the characterization of endosialin/TEM-1.
Daniel J O'Shannessy, Michael F Smith, Elizabeth B Somers, Stephen M Jackson, Earl Albone

Oncotarget· October 2016

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Derivatization of agelastatin A leading to bioactive analogs and a trifunctional probe.
Morgan Jouanneau, Brandon McClary, Jeremy Chris P Reyes, Rong Chen, Yuling Chen, Earl F Albone

Bioorg Med Chem Lett· April 2016

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Targeting endosialin/CD248 through antibody-mediated internalization results in impaired pericyte maturation and dysfunctional tumor microvasculature.
Katherine Rybinski, Hongxia Z Imtiyaz, Barrie Mittica, Brian Drozdowski, James Fulmer, Earl Albone

Oncotarget· September 2015

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Co-development of diagnostic vectors to support targeted therapies and theranostics: essential tools in personalized cancer therapy.
Nicholas C Nicolaides, Daniel J O'Shannessy, Earl Albone, Luigi Grasso

Front Oncol· July 2014

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The antitumor activity of the human FOLR1-specific monoclonal antibody, farletuzumab, in an ovarian cancer mouse model is mediated by antibody-dependent cellular cytotoxicity.
JianMin Lin, Jared L Spidel, Christopher J Maddage, Katherine A Rybinski, Rina P Kennedy, Earl F Albone

Cancer Biol Ther· November 2013

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Bioconjugation by native chemical tagging of C-H bonds.
Qianghui Zhou, Jinghan Gui, Chung-Mao Pan, Earl Albone, Xin Cheng

J Am Chem Soc· September 2013

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Characterization of the human folate receptor alpha via novel antibody-based probes.
Daniel J O'Shannessy, Elizabeth B Somers, Earl Albone, Xin Cheng, Young Chul Park

Oncotarget· December 2011

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Effect of chelator conjugation level and injection dose on tumor and organ uptake of 111In-labeled MORAb-009, an anti-mesothelin antibody.
In Soo Shin, Sang-Myung Lee, Hyung Sub Kim, Zhengsheng Yao, Celeste Regino, Earl F Albone

Nucl Med Biol· November 2011

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Single dose GLP-1-Tf ameliorates myocardial ischemia/reperfusion injury.
Muneaki Matsubara, Shinya Kanemoto, Bradley G Leshnower, Earl F Albone, Robin Hinmon

J Surg Res· January 2011

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Generation and characterization of high affinity human monoclonal antibodies that neutralize staphylococcal enterotoxin B.
Brian Drozdowski, Yuhong Zhou, Brad Kline, Jared Spidel, Yin Yin Chan, Earl Albone

J Immune Based Ther Vaccines· December 2010

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Synergistic effects of combined therapy using paclitaxel and [90Y-DOTA]776.1 on growth of OVCAR-3 ovarian carcinoma xenografts.
Gregg R Masters, Marc A Berger, Earl F Albone

Gynecol Oncol· September 2006

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Characterization of antibodies to CA 125 that bind preferentially to the cell-associated form of the antigen.
Judith Singleton, Darlene E Guillen, Michael S Scully, Jiyan Xue, Jennifer Moffet, Earl F Albone

Tumour Biol· June 2006

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Pharmacokinetics, biodistribution, and radioimmunotherapy with monoclonal antibody 776.1 in a murine model of human ovarian cancer.
Marc A Berger, Gregg R Masters, Judith Singleton, Michael S Scully, Lisa G Grimm, Earl F Albone

Cancer Biother Radiopharm· December 2005

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