Publications by authors named "Edward Browne"

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Customizable mRNA Lipid Nanoparticles for Transfection of Primary Human T Cells.
Rachel VanKeulen-Miller, Julia Huff, Eshan A Narasipura, Edward P Browne, Owen S Fenton

ACS Nano· December 2025

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Single cell characterization of the gastrointestinal HIV reservoir reveals heterogeneous cellular phenotypes.
Jackson J Peterson, Shipra Chandel, Katherine James, Elizabeth S Bennett, Vincent Wu, Edward P Browne

J Clin Invest· December 2025

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SARS-CoV-2 infection induces pro-fibrotic and pro-thrombotic foam cell formation.
Diana M Battaglia, Claire E Post, Wenbo Yao, Angela Wahl, Lisa E Gralinski, Edward P Browne

Nat Microbiol· October 2025

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Using single cell technologies to understand HIV latency models.
Julia S Huff, Edward P Browne

Curr Opin HIV AIDS· September 2025

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HIV-1 accessory protein Vpr possesses a cryptic p300-dependent transcription-promoting activity that is blocked by histone deacetylases in CD4+ T cells.
Catherine A Lewis, David M Margolis, Edward P Browne

PLoS Pathog· September 2025

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The role of Tat in HIV latency and reactivation.
David M Margolis, Edward P Browne

Front Immunol· September 2025

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Persistent type I interferon signaling within the brain of people with HIV on ART with cognitive impairment.
Yuyang Tang, Ling Xie, Ciniso Sylvester Shabangu, Dajiang Li, Gabriela da Silva Prates, Edward P Browne

PLoS Pathog· August 2025

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Single cell multiomic analysis of the impact of Delta-9-tetrahydrocannabinol on HIV infected CD4 T cells.
Manickam Ashokkumar, Renee Y Ge, Alicia Cooper-Volkheimer, David M Margolis, Quefeng Li, Edward P Browne

bioRxiv· June 2025

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Single cell analysis of HIV expression and integration sites reveals robust viral expression across diverse chromatin environments.
Yun Ma, Jackson J Peterson, David M Margolis, Edward P Browne

bioRxiv· June 2025

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A screen of chromatin-targeting compounds identifies TAF1 as a novel regulator of HIV latency.
Samuel D Burgos, Airlie M Ward, Manickam Ashokkumar, Kimberly P Enders, Lindsey I James, Edward P Browne

bioRxiv· May 2025

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A targeted CRISPR screen identifies ETS1 as a regulator of HIV-1 latency.
Manickam Ashokkumar, Terry L Hafer, Abby Felton, Nancie M Archin, David M Margolis, Edward P Browne

PLoS Pathog· April 2025

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Integrator complex subunit 12 knockout overcomes a transcriptional block to HIV latency reversal.
Carley N Gray, Manickam Ashokkumar, Derek H Janssens, Jennifer L Kirchherr, Brigitte Allard, Edward P Browne

Elife· April 2025

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Integrator complex subunit 12 knockout overcomes a transcriptional block to HIV latency reversal.
Carley N Gray, Manickam Ashokkumar, Derek H Janssens, Jennifer Kirchherr, Brigitte Allard, Edward P Browne

bioRxiv· February 2025

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NF-κB dependent gene expression and plasma IL-1β, TNFα and GCSF drive transcriptomic diversity and CD4:CD8 ratio in people with HIV on ART.
Yingfan Wang, German G Gornalusse, David A Siegel, Alton Barbehenn, Rebecca Hoh, Edward P Browne

bioRxiv· February 2025

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They Will Come, You Must Build It: A Modified Delphi Process Applied to Preparing Acute Care Facilities Infrastructure for High-Consequence Infectious Diseases.
Justin Chan, Eileen F Searle, Dmitry Khodyakov, Logan Denson, Andrea Echeverri, Edward M Browne

Health Secur· October 2024

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Analysis of the effect of HDAC inhibitors on the formation of the HIV reservoir.
Lijun Ling, Manse Kim, Andrew Soper, Martina Kovarova, Rae Ann Spagnuolo, Edward P Browne

mBio· September 2024

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Machine learning approaches identify immunologic signatures of total and intact HIV DNA during long-term antiretroviral therapy.
Lesia Semenova, Yingfan Wang, Shane Falcinelli, Nancie Archin, Alicia D Cooper-Volkheimer, Edward P Browne

Elife· September 2024

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A targeted CRISPR screen identifies ETS1 as a regulator of HIV latency.
Manickam Ashokkumar, Terry L Hafer, Abby Felton, Nancie M Archin, David M Margolis, Edward P Browne

bioRxiv· August 2024

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Machine learning approaches identify immunologic signatures of total and intact HIV DNA during long-term antiretroviral therapy.
Lesia Semenova, Yingfan Wang, Shane Falcinelli, Nancie Archin, Alicia D Cooper-Volkheimer, Edward P Browne

bioRxiv· June 2024

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The histone methyltransferase SETD2 regulates HIV expression and latency.
Cameron R Bussey-Sutton, Airlie Ward, Joshua A Fox, Anne-Marie W Turner, Jackson J Peterson, Edward P Browne

PLoS Pathog· June 2024

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Integrated Single-cell Multiomic Analysis of HIV Latency Reversal Reveals Novel Regulators of Viral Reactivation.
Manickam Ashokkumar, Wenwen Mei, Jackson J Peterson, Yuriko Harigaya, David M Murdoch, Edward P Browne

Genomics Proteomics Bioinformatics· May 2024

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The Rashomon Importance Distribution: Getting RID of Unstable, Single Model-based Variable Importance.
Jon Donnelly, Srikar Katta, Cynthia Rudin, Edward P Browne

ArXiv· April 2024

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A novel high-throughput microwell outgrowth assay for HIV-infected cells.
Anthony D Fenton, Nancie Archin, Anne-Marie Turner, Sarah Joseph, Matthew Moeser, Edward P Browne

J Virol· March 2024

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Azetidines Kill Multidrug-Resistant without Detectable Resistance by Blocking Mycolate Assembly.
Yixin Cui, Alice Lanne, Xudan Peng, Edward Browne, Apoorva Bhatt

J Med Chem· February 2024

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A histone deacetylase network regulates epigenetic reprogramming and viral silencing in HIV-infected cells.
Jackson J Peterson, Catherine A Lewis, Samuel D Burgos, Ashokkumar Manickam, Yinyan Xu, Edward P Browne

Cell Chem Biol· December 2023

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