Publications by authors named "Shane Falcinelli"

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Reduction of resources with mRNA host-response whole blood testing on patients presenting to the emergency department with suspected infections: a retrospective analysis of 30 cases.
Alan H B Wu, Shane Falcinelli, Rama Yakubu

J Med Microbiol· October 2025

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Correction for Raines et al., "Nanoparticle delivery of Tat synergizes with classical latency reversal agents to express HIV antigen targets".
Samuel L M Raines, Shane D Falcinelli, Jackson J Peterson, Ellen Van Gulck, Brigitte Allard

Antimicrob Agents Chemother· August 2025

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BET degraders reveal BRD4 disruption of 7SK and P-TEFb is critical for effective reactivation of latent HIV in CD4+ T-cells.
Anne-Marie W Turner, Frances M Bashore, Shane D Falcinelli, Joshua A Fox, Alana L Keller

J Virol· April 2025

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Recurrent Fever and Back Pain Associated With Septic Shock in a Healthy 16-Year-Old Girl.
Shane D Falcinelli, Emma Hignett, Eric Zwemer, Patrick O'Shea

Pediatr Rev· March 2025

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Machine learning approaches identify immunologic signatures of total and intact HIV DNA during long-term antiretroviral therapy.
Lesia Semenova, Yingfan Wang, Shane Falcinelli, Nancie Archin, Alicia D Cooper-Volkheimer

Elife· September 2024

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Nanoparticle delivery of Tat synergizes with classical latency reversal agents to express HIV antigen targets.
Samuel L M Raines, Shane D Falcinelli, Jackson J Peterson, Ellen Van Gulck, Brigitte Allard

Antimicrob Agents Chemother· July 2024

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Machine learning approaches identify immunologic signatures of total and intact HIV DNA during long-term antiretroviral therapy.
Lesia Semenova, Yingfan Wang, Shane Falcinelli, Nancie Archin, Alicia D Cooper-Volkheimer

bioRxiv· June 2024

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The Effects of Human Immunodeficiency Virus Type 1 (HIV-1) Antigen-Expanded Specific T-Cell Therapy and Vorinostat on Persistent HIV-1 Infection in People With HIV on Antiretroviral Therapy.
Cynthia L Gay, Patrick J Hanley, Shane D Falcinelli, JoAnn D Kuruc, Susan M Pedersen

J Infect Dis· March 2024

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Transient CD4+ T cell depletion during suppressive ART reduces the HIV reservoir in humanized mice.
Lijun Ling, Chandrav De, Rae Ann Spagnuolo, Nurjahan Begum, Shane D Falcinelli

PLoS Pathog· December 2023

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Impact of Cannabis Use on Immune Cell Populations and the Viral Reservoir in People With HIV on Suppressive Antiretroviral Therapy.
Shane D Falcinelli, Alicia D Cooper-Volkheimer, Lesia Semenova, Ethan Wu, Alexander Richardson

J Infect Dis· November 2023

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HIVepsilon-seq-scalable characterization of intact persistent proviral HIV reservoirs in women.
Kirston Barton, James M Ferguson, Ira W Deveson, Shane D Falcinelli, Katherine S James

J Virol· November 2023

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AZD5582 plus SIV-specific antibodies reduce lymph node viral reservoirs in antiretroviral therapy-suppressed macaques.
Amir Dashti, Sophia Sukkestad, Anna M Horner, Margaret Neja, Zain Siddiqi, Shane D Falcinelli

Nat Med· October 2023

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Combined noncanonical NF-κB agonism and targeted BET bromodomain inhibition reverse HIV latency ex vivo.
Shane D Falcinelli, Jackson J Peterson, Anne-Marie W Turner, David Irlbeck, Jenna Read

J Clin Invest· April 2022

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Stable Latent HIV Infection and Low-level Viremia Despite Treatment With the Broadly Neutralizing Antibody VRC07-523LS and the Latency Reversal Agent Vorinostat.
Cynthia L Gay, Katherine S James, Marina Tuyishime, Shane D Falcinelli, Sarah B Joseph

J Infect Dis· March 2022

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Crotonylation sensitizes IAPi-induced disruption of latent HIV by enhancing p100 cleavage into p52.
Dajiang Li, Morgan G Dewey, Li Wang, Shane D Falcinelli, Lilly M Wong

iScience· January 2022

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Longitudinal Dynamics of Intact HIV Proviral DNA and Outgrowth Virus Frequencies in a Cohort of Individuals Receiving Antiretroviral Therapy.
Shane D Falcinelli, Kayla W Kilpatrick, Jenna Read, Ross Murtagh, Brigitte Allard

J Infect Dis· July 2021

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Sequence Evaluation and Comparative Analysis of Novel Assays for Intact Proviral HIV-1 DNA.
Christian Gaebler, Shane D Falcinelli, Elina Stoffel, Jenna Read, Ross Murtagh

J Virol· February 2021

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Impact of Biological Sex on Immune Activation and Frequency of the Latent HIV Reservoir During Suppressive Antiretroviral Therapy.
Shane D Falcinelli, Bonnie E Shook-Sa, Morgan G Dewey, Sumati Sridhar, Jenna Read

J Infect Dis· November 2020

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Cellular Gene Modulation of HIV-Infected CD4 T Cells in Response to Serial Treatment with the Histone Deacetylase Inhibitor Vorinostat.
Jill W Maxwell, Shane D Falcinelli, Alexey Nefedov, Corin Dorfmeier, Guoxin Wu

J Virol· June 2020

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CTLA-4 and PD-1 dual blockade induces SIV reactivation without control of rebound after antiretroviral therapy interruption.
Justin Harper, Shari Gordon, Chi Ngai Chan, Hong Wang, Emily Lindemuth, Shane D Falcinelli

Nat Med· April 2020

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Assessing the impact of AGS-004, a dendritic cell-based immunotherapy, and vorinostat on persistent HIV-1 Infection.
Cynthia L Gay, Joann D Kuruc, Shane D Falcinelli, Joanna A Warren, Sarah A Reifeis

Sci Rep· March 2020

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Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo.
Christopher C Nixon, Maud Mavigner, Gavin C Sampey, Alyssa D Brooks, Rae Ann Spagnuolo, Shane D Falcinelli

Nature· February 2020

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New Frontiers in Measuring and Characterizing the HIV Reservoir.
Shane D Falcinelli, Cristina Ceriani, David M Margolis, Nancie M Archin

Front Microbiol· December 2019

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Characterization of Host and Bacterial Contributions to Lung Barrier Dysfunction Following Co-infection with 2009 Pandemic Influenza and Methicillin Resistant .
Michaela E Nickol, Justine Ciric, Shane D Falcinelli, Daniel S Chertow, Jason Kindrachuk

Viruses· January 2019

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The Madagascar Hissing Cockroach as an Alternative Non-mammalian Animal Model to Investigate Virulence, Pathogenesis, and Drug Efficacy.
Jennifer Chua, Nathan A Fisher, Shane D Falcinelli, David DeShazer, Arthur M Friedlander

J Vis Exp· November 2017

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