Publications by authors named "Edward Dul"

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A687V EZH2 is a driver of histone H3 lysine 27 (H3K27) hypertrimethylation.
Heidi M Ott, Alan P Graves, Melissa B Pappalardi, Michael Huddleston, Wendy S Halsey, Edward Dul

Mol Cancer Ther· December 2014

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Development of a high-throughput screen to detect inhibitors of TRPS1 sumoylation.
Martin Brandt, Lawrence M Szewczuk, Hong Zhang, Xuan Hong, Patricia M McCormick, Edward Dul

Assay Drug Dev Technol· June 2013

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Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27).
Michael T McCabe, Alan P Graves, Gopinath Ganji, Elsie Diaz, Wendy S Halsey, Edward Dul

Proc Natl Acad Sci U S A· February 2012

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Potent, selective and orally bioavailable dihydropyrimidine inhibitors of Rho kinase (ROCK1) as potential therapeutic agents for cardiovascular diseases.
Clark A Sehon, Gren Z Wang, Andrew Q Viet, Krista B Goodman, Sarah E Dowdell, Edward Dul

J Med Chem· November 2008

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Novel Rho kinase inhibitors with anti-inflammatory and vasodilatory activities.
Chris Doe, Ross Bentley, David J Behm, Robert Lafferty, Robert Stavenger, Edward Dul

J Pharmacol Exp Ther· January 2007

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Discovery of aminofurazan-azabenzimidazoles as inhibitors of Rho-kinase with high kinase selectivity and antihypertensive activity.
Robert A Stavenger, Haifeng Cui, Sarah E Dowdell, Robert G Franz, Dimitri E Gaitanopoulos, Edward Dul

J Med Chem· January 2007

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Development of dihydropyridone indazole amides as selective Rho-kinase inhibitors.
Krista B Goodman, Haifeng Cui, Sarah E Dowdell, Dimitri E Gaitanopoulos, Robert L Ivy, Edward Dul

J Med Chem· January 2007

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Radioligand binding and functional characterization of recombinant human NmU1 and NmU2 receptors stably expressed in clonal human embryonic kidney-293 cells.
Nambi Aiyar, Jyoti Disa, James J Foley, Peter T Buckley, William E Wixted, Edward Dul

Pharmacology· September 2004

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Identification of novel isoform-selective inhibitors within class I histone deacetylases.
Erding Hu, Edward Dul, Chiu-Mei Sung, Zunxuan Chen, Robert Kirkpatrick

J Pharmacol Exp Ther· November 2003

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