Publications by authors named "Edward Hammond"

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Preclinical Evaluation of [Pb]Pb-ADVC001: A Prostate-Specific Membrane Antigen-Targeted α-Therapy for Prostate Cancer.
Feifei Liu, Melissa E Monterosso, Didier Boucher, Stelle Shakti, Kwong Ching Li, Edward Hammond

J Nucl Med· November 2025

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The new big is small: Leveraging knowledge from small trials for rare disease drug development: Blarcamesine for Rett syndrome.
Ene I Ette, Emmanuel O Fadiran, Christopher Missling, Edward Hammond

Br J Clin Pharmacol· April 2025

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Implementing governmental oversight of enhanced potential pandemic pathogen research.
Richard H Ebright, Raina MacIntyre, Joseph P Dudley, Colin D Butler, Andre Goffinet, Edward Hammond

J Virol· April 2024

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Population-Based Characterization of the Pharmacokinetics and Food Effect of ANAVEX3-71, a Novel Sigma-1 Receptor and Allosteric M1 Muscarinic Receptor Agonist in Development for Treatment of Frontotemporal Dementia, Schizophrenia, and Alzheimer Disease.
Emmanuel O Fadiran, Edward Hammond, James Tran, Christopher U Missling, Ene Ette

Clin Pharmacol Drug Dev· January 2024

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Concentration-QTc Relationship from a Single Ascending Dose Study of ANAVEX3-71, a Novel Sigma-1 Receptor and Allosteric M1 Muscarinic Receptor Agonist in Development for the Treatment of Frontotemporal Dementia, Schizophrenia, and Alzheimer's Disease.
Emmanuel O Fadiran, Edward Hammond, James Tran, Hongqi Xue, Janell Chen

Clin Pharmacol Drug Dev· September 2023

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PG545 sensitizes ovarian cancer cells to PARP inhibitors through modulation of RAD51-DEK interaction.
Upasana Ray, Prabhu Thirusangu, Ling Jin, Yinan Xiao, Christopher L Pathoulas, Edward Hammond

Oncogene· September 2023

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Phase Ib open-label, multicenter study of pixatimod, an activator of TLR9, in combination with nivolumab in subjects with microsatellite-stable metastatic colorectal cancer, metastatic pancreatic ductal adenocarcinoma and other solid tumors.
Charlotte Lemech, Keith Dredge, Darryn Bampton, Edward Hammond, Andrew Clouston

J Immunother Cancer· January 2023

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An Enzymatic Activity Assay for Heparanase That Is Useful for Evaluating Clinically Relevant Inhibitors and Studying Kinetics.
Edward Hammond, Vito Ferro

Methods Mol Biol· January 2023

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Health care utilization and costs of systemic lupus erythematosus in the United States: A systematic review.
Dora H Lin, Irene B Murimi-Worstell, Hong Kan, Jonothan C Tierce, Xia Wang, Edward R Hammond

Lupus· June 2022

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Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 by Disrupting the Spike-ACE2 Interaction.
Scott E Guimond, Courtney J Mycroft-West, Neha S Gandhi, Julia A Tree, Thuy T Le, Edward Hammond

ACS Cent Sci· May 2022

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Risk of malignancy in patients with systemic lupus erythematosus: Systematic review and meta-analysis.
Ann E Clarke, Nick Pooley, Zoe Marjenberg, Julia Langham, Lindsay Nicholson, Edward R Hammond

Semin Arthritis Rheum· December 2021

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Disease and economic burden increase with systemic lupus erythematosus severity 1 year before and after diagnosis: a real-world cohort study, United States, 2004-2015.
Miao Jiang, Aimee M Near, Barnabas Desta, Xia Wang, Edward R Hammond

Lupus Sci Med· September 2021

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Frequency, severity and costs of flares increase with disease severity in newly diagnosed systemic lupus erythematosus: a real-world cohort study, United States, 2004-2015.
Edward R Hammond, Barnabas Desta, Aimee M Near, Xia Wang, Miao Jiang

Lupus Sci Med· September 2021

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Health-care utilization and costs in adults with systemic lupus erythematosus in the United Kingdom: a real-world observational retrospective cohort analysis.
Mihail Samnaliev, Volkan Barut, Sharada Weir, Julia Langham, Sue Langham, Edward Hammond

Rheumatol Adv Pract· September 2021

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Disease severity, flares and treatment patterns in adults with systemic lupus erythematosus in the UK: a real-world observational retrospective cohort analysis.
Julia Langham, Volkan Barut, Mihail Samnaliev, Sue Langham, Sharada Weir, Edward Hammond

Rheumatol Adv Pract· August 2021

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Evidence of a putative glycosaminoglycan binding site on the glycosylated SARS-CoV-2 spike protein N-terminal domain.
Zachariah P Schuurs, Edward Hammond, Stefano Elli, Timothy R Rudd, Courtney J Mycroft-West

Comput Struct Biotechnol J· May 2021

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Healthcare Utilization and Costs of Systemic Lupus Erythematosus by Disease Severity in the United States.
Irene B Murimi-Worstell, Dora H Lin, Hong Kan, Jonothan Tierce, Xia Wang, Edward R Hammond

J Rheumatol· March 2021

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The Burden of Systemic Lupus Erythematosus in Germany: Incidence, Prevalence, and Healthcare Resource Utilization.
Andreas Schwarting, Heiko Friedel, Elena Garal-Pantaler, Marc Pignot, Xia Wang, Edward R Hammond

Rheumatol Ther· March 2021

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The risk of infections in adult patients with systemic lupus erythematosus: systematic review and meta-analysis.
José María Pego-Reigosa, Lindsay Nicholson, Nick Pooley, Sue Langham, Nina Embleton, Edward R Hammond

Rheumatology (Oxford)· January 2021

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Association Between Patient- and Physician-Reported Outcomes in Patients with Moderate-To-Severe Plaque Psoriasis Treated with Biologics in Real Life (PSO-BIO-REAL).
Jean-Philippe Lacour, Anthony Bewley, Edward Hammond, Jes B Hansen, Laura Horne

Dermatol Ther (Heidelb)· October 2020

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Study protocol for the international Systemic Lupus Erythematosus Prospective Observational Cohort Study (SPOCS): understanding lupus and the role of type I interferon gene signature.
Edward R Hammond, Raj Tummala, Anna Berglind, Farhat Syed, Xia Wang

BMJ Open· September 2020

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Systemic lupus erythematosus; stroke and myocardial infarction risk: a systematic review and meta-analysis.
Jinoos Yazdany, Nick Pooley, Julia Langham, Lindsay Nicholson, Sue Langham, Edward Hammond

RMD Open· September 2020

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Sulfated glycolipid PG545 induces endoplasmic reticulum stress and augments autophagic flux by enhancing anticancer chemotherapy efficacy in endometrial cancer.
Robert Hoffmann, Sayantani Sarkar Bhattacharya, Debarshi Roy, Boris Winterhoff, Ralf Schmidmaier, Edward Hammond

Biochem Pharmacol· August 2020

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Heparanase Inhibition by Pixatimod (PG545): Basic Aspects and Future Perspectives.
Edward Hammond, Keith Dredge

Adv Exp Med Biol· July 2020

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Association between organ damage and mortality in systemic lupus erythematosus: a systematic review and meta-analysis.
Irene B Murimi-Worstell, Dora H Lin, Henk Nab, Hong J Kan, Oluwadamilola Onasanya, Edward R Hammond

BMJ Open· May 2020

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