Publications by authors named "Edward Rebar"

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In vivo gene editing of human hematopoietic stem and progenitor cells using envelope-engineered virus-like particles.
Vladimir V Botchkarev, Sean Harrington, Matteo Stoppato, Alexander Justen, Casey Kimber, Edward J Rebar

Nat Biotechnol· December 2025

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Persistent repression of tau in the brain using engineered zinc finger protein transcription factors.
Susanne Wegmann, Sarah L DeVos, Bryan Zeitler, Kimberly Marlen, Rachel E Bennett, Edward J Rebar

Sci Adv· March 2021

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Enhancing gene editing specificity by attenuating DNA cleavage kinetics.
Jeffrey C Miller, Deepak P Patil, Danny F Xia, Charles B Paine, Friedrich Fauser, Edward J Rebar

Nat Biotechnol· August 2019

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Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington's disease.
Bryan Zeitler, Steven Froelich, Kimberly Marlen, David A Shivak, Qi Yu, Edward J Rebar

Nat Med· July 2019

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Diversifying the structure of zinc finger nucleases for high-precision genome editing.
David E Paschon, Stephanie Lussier, Tenzin Wangzor, Danny F Xia, Patrick W Li, Edward J Rebar

Nat Commun· March 2019

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Gene editing of the multi-copy H2A.B gene and its importance for fertility.
Nur Diana Anuar, Sebastian Kurscheid, Matt Field, Lei Zhang, Edward Rebar

Genome Biol· January 2019

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Genome editing in mitochondria corrects a pathogenic mtDNA mutation in vivo.
Payam A Gammage, Carlo Viscomi, Marie-Lune Simard, Ana S H Costa, Edoardo Gaude, Edward J Rebar

Nat Med· November 2018

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Long-Term Engraftment and Fetal Globin Induction upon Gene Editing in Bone-Marrow-Derived CD34 Hematopoietic Stem and Progenitor Cells.
Kai-Hsin Chang, Sarah E Smith, Timothy Sullivan, Kai Chen, Qianhe Zhou, Edward J Rebar

Mol Ther Methods Clin Dev· March 2017

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Gene Correction of iPSCs from a Wiskott-Aldrich Syndrome Patient Normalizes the Lymphoid Developmental and Functional Defects.
Tamara J Laskowski, Yasmine Van Caeneghem, Rasoul Pourebrahim, Chao Ma, Zhenya Ni, Edward J Rebar

Stem Cell Reports· August 2016

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Long-term multilineage engraftment of autologous genome-edited hematopoietic stem cells in nonhuman primates.
Christopher W Peterson, Jianbin Wang, Krystin K Norman, Zachary K Norgaard, Olivier Humbert, Edward J Rebar

Blood· May 2016

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Mammalian interspecies substitution of immune modulatory alleles by genome editing.
Simon G Lillico, Chris Proudfoot, Tim J King, Wenfang Tan, Lei Zhang, Edward J Rebar

Sci Rep· February 2016

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Genetic editing of HLA expression in hematopoietic stem cells to broaden their human application.
Hiroki Torikai, Tiejuan Mi, Loren Gragert, Martin Maiers, Amer Najjar, Edward J Rebar

Sci Rep· February 2016

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Multi-reporter selection for the design of active and more specific zinc-finger nucleases for genome editing.
Benjamin L Oakes, Danny F Xia, Elizabeth F Rowland, Denise J Xu, Irina Ankoudinova, Edward J Rebar

Nat Commun· January 2016

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In vivo genome editing of the albumin locus as a platform for protein replacement therapy.
Rajiv Sharma, Xavier M Anguela, Yannick Doyon, Thomas Wechsler, Russell C DeKelver, Edward J Rebar

Blood· October 2015

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Functional footprinting of regulatory DNA.
Jeff Vierstra, Andreas Reik, Kai-Hsin Chang, Sandra Stehling-Sun, Yuanyue Zhou, Edward J Rebar

Nat Methods· October 2015

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Clinical Scale Zinc Finger Nuclease-mediated Gene Editing of PD-1 in Tumor Infiltrating Lymphocytes for the Treatment of Metastatic Melanoma.
Joal D Beane, Gary Lee, Zhili Zheng, Matthew Mendel, Daniel Abate-Daga, Edward J Rebar

Mol Ther· August 2015

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Improved specificity of TALE-based genome editing using an expanded RVD repertoire.
Jeffrey C Miller, Lei Zhang, Danny F Xia, John J Campo, Irina V Ankoudinova, Edward J Rebar

Nat Methods· May 2015

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Correction of the sickle cell disease mutation in human hematopoietic stem/progenitor cells.
Megan D Hoban, Gregory J Cost, Matthew C Mendel, Zulema Romero, Michael L Kaufman, Edward J Rebar

Blood· April 2015

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Human intestinal tissue with adult stem cell properties derived from pluripotent stem cells.
Ryan Forster, Kunitoshi Chiba, Lorian Schaeffer, Samuel G Regalado, Christine S Lai, Edward J Rebar

Stem Cell Reports· June 2014

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Mitochondrially targeted ZFNs for selective degradation of pathogenic mitochondrial genomes bearing large-scale deletions or point mutations.
Payam A Gammage, Joanna Rorbach, Anna I Vincent, Edward J Rebar, Michal Minczuk

EMBO Mol Med· April 2014

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Trait stacking via targeted genome editing.
William M Ainley, Lakshmi Sastry-Dent, Mary E Welter, Michael G Murray, Bryan Zeitler, Edward J Rebar

Plant Biotechnol J· December 2013

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Toward eliminating HLA class I expression to generate universal cells from allogeneic donors.
Hiroki Torikai, Andreas Reik, Frank Soldner, Edus H Warren, Carrie Yuen, Edward J Rebar

Blood· August 2013

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Translating dosage compensation to trisomy 21.
Jun Jiang, Yuanchun Jing, Gregory J Cost, Jen-Chieh Chiang, Heather J Kolpa, Edward J Rebar

Nature· August 2013

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Site-specific genome editing in Plasmodium falciparum using engineered zinc-finger nucleases.
Judith Straimer, Marcus C S Lee, Andrew H Lee, Bryan Zeitler, April E Williams, Edward J Rebar

Nat Methods· October 2012

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A designed zinc-finger transcriptional repressor of phospholamban improves function of the failing heart.
H Steve Zhang, Dingang Liu, Yan Huang, Stefan Schmidt, Reed Hickey, Edward J Rebar

Mol Ther· August 2012

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