Publications by authors named "Edwin A Lewis"

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Disruption of microtubule function in cultured human cells by a cytotoxic ruthenium(ii) polypyridyl complex.
Nagham Alatrash, Faiza H Issa, Nada S Bawazir, Savannah J West, Kathleen E Van Manen-Brush, Edwin A Lewis

Chem Sci· November 2019

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Effects of Doxorubicin on the Liquid-Liquid Phase Change Properties of Elastin-Like Polypeptides.
Valeria Zai-Rose, Savannah J West, Wolfgang H Kramer, G Reid Bishop, Edwin A Lewis

Biophys J· October 2018

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Berenil Binds Tightly to Parallel and Mixed Parallel/Antiparallel G-Quadruplex Motifs with Varied Thermodynamic Signatures.
Clinton G Mikek, Savannah J West, J Cole Gwin, Neetu Dayal, Herman O Sintim, Edwin A Lewis

ACS Omega· September 2018

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Global stability of an α-ketoglutarate-dependent dioxygenase (TauD) and its related complexes.
Kate L Henderson, Mingjie Li, Salette Martinez, Edwin A Lewis, Robert P Hausinger

Biochim Biophys Acta Gen Subj· May 2017

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ITC Methods for Assessing Buffer/Protein Interactions from the Perturbation of Steady-State Kinetics: A Reactivity Study of Homoprotocatechuate 2,3-Dioxygenase.
Kate L Henderson, Delta K Boyles, Vu H Le, Edwin A Lewis, Joseph P Emerson

Methods Enzymol· October 2016

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Alkyne-substituted diminazene as G-quadruplex binders with anticancer activities.
Changhao Wang, Brandon Carter-Cooper, Yixuan Du, Jie Zhou, Musabbir A Saeed, Edwin A Lewis

Eur J Med Chem· August 2016

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Thermodynamics of substrate binding to the metal site in homoprotocatechuate 2,3-dioxygenase: Using ITC under anaerobic conditions to study enzyme-substrate interactions.
Kate L Henderson, Danielle H Francis, Edwin A Lewis, Joseph P Emerson

Biochim Biophys Acta· May 2016

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Calorimetric and spectroscopic investigations of the binding of metallated porphyrins to G-quadruplex DNA.
Jesse I DuPont, Kate L Henderson, Amanda Metz, Vu H Le, Joseph P Emerson, Edwin A Lewis

Biochim Biophys Acta· May 2016

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Bcl-2 promoter sequence G-quadruplex interactions with three planar and non-planar cationic porphyrins: TMPyP4, TMPyP3, and TMPyP2.
Vu H Le, Narayana Nagesh, Edwin A Lewis

PLoS One· January 2015

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Thermodynamic investigations of [(phen)2Ru(tatpp)Ru(phen)2](4+) interactions with B-DNA.
Vu H Le, Matthew R McGuire, Pooja Ahuja, Frederick M MacDonnell, Edwin A Lewis

J Phys Chem B· January 2015

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Diminazene or berenil, a classic duplex minor groove binder, binds to G-quadruplexes with low nanomolar dissociation constants and the amidine groups are also critical for G-quadruplex binding.
Jie Zhou, Vu Le, Dimpy Kalia, Shizuka Nakayama, Clinton Mikek, Edwin A Lewis

Mol Biosyst· October 2014

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Thermodynamics of host-guest interactions between fullerenes and a buckycatcher.
Vu H Le, Michael Yanney, Matthew McGuire, Andrzej Sygula, Edwin A Lewis

J Phys Chem B· October 2014

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Effect of basic cell-penetrating peptides on the structural, thermodynamic, and hydrodynamic properties of a novel drug delivery vector, ELP[V5G3A2-150].
Daniel F Lyons, Vu Le, Wolfgang H Kramer, Gene L Bidwell, Edwin A Lewis

Biochemistry· February 2014

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The effect of pyridyl substituents on the thermodynamics of porphyrin binding to G-quadruplex DNA.
Gerald B Rowland, Kerry Barnett, Jesse I Dupont, Gopalakrishna Akurathi, Vu H Le, Edwin A Lewis

Bioorg Med Chem· December 2013

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Role of water in netropsin binding to an A(2)T(2) hairpin DNA site: osmotic stress experiments.
Joseph P Ramos, Vu H Le, Edwin A Lewis

J Phys Chem B· December 2013

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The effect of molecular crowding on the stability of human c-MYC promoter sequence I-motif at neutral pH.
Jingjing Cui, Phillip Waltman, Vu H Le, Edwin A Lewis

Molecules· October 2013

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Building reactive copper centers in human carbonic anhydrase II.
He Song, Andrew C Weitz, Michael P Hendrich, Edwin A Lewis, Joseph P Emerson

J Biol Inorg Chem· August 2013

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Structural and hydrodynamic analysis of a novel drug delivery vector: ELP[V5G3A2-150].
Daniel F Lyons, Vu Le, Gene L Bidwell, Wolfgang H Kramer, Edwin A Lewis

Biophys J· May 2013

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Modeling complex equilibria in isothermal titration calorimetry experiments: thermodynamic parameters estimation for a three-binding-site model.
Vu H Le, Robert Buscaglia, Jonathan B Chaires, Edwin A Lewis

Anal Biochem· March 2013

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Exploring substrate binding in homoprotocatechuate 2,3-dioxygenase using isothermal titration calorimetry.
Kate L Henderson, Vu H Le, Edwin A Lewis, Joseph P Emerson

J Biol Inorg Chem· October 2012

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Revisiting zinc coordination in human carbonic anhydrase II.
He Song, David L Wilson, Erik R Farquhar, Edwin A Lewis, Joseph P Emerson

Inorg Chem· October 2012

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Complexity in the binding of minor groove agents: netropsin has two thermodynamically different DNA binding modes at a single site.
Edwin A Lewis, Manoj Munde, Shuo Wang, Michael Rettig, Vu Le

Nucleic Acids Res· December 2011

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Effect of Ionic Strength on Porphyrin Drugs Interaction with Quadruplex DNA Formed by the Promoter Region of C-myc and Bcl2 Oncogenes.
Narayana Nagesh, Varun K Sharma, A Ganesh Kumar, Edwin A Lewis

J Nucleic Acids· July 2011

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DSC deconvolution of the structural complexity of c-MYC P1 promoter G-quadruplexes.
Jamie M Dettler, Robert Buscaglia, Vu H Le, Edwin A Lewis

Biophys J· March 2011

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Biophysical characterization of an ensemble of intramolecular i-motifs formed by the human c-MYC NHE III1 P1 promoter mutant sequence.
Jamie M Dettler, Robert Buscaglia, Jingjing Cui, Derek Cashman, Meredith Blynn, Edwin A Lewis

Biophys J· July 2010

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