Publications by authors named "Edwin Jao"

Claim this Profile
T
Toward the back-up of boceprevir (SCH 503034): discovery of new extended P4-capped ketoamide inhibitors of hepatitis C virus NS3 serine protease with improved potency and pharmacokinetic profiles.
Stéphane L Bogen, Weidong Pan, Sumei Ruan, Latha G Nair, Ashok Arasappan, Edwin Jao

J Med Chem· June 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Toward second generation hepatitis C virus NS3 serine protease inhibitors: discovery of novel P4 modified analogues with improved potency and pharmacokinetic profile.
Ashok Arasappan, Angela I Padilla, Edwin Jao, Frank Bennett, Stephane L Bogen

J Med Chem· May 2009

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
K
Key steps in the structure-based optimization of the hepatitis C virus NS3/4A protease inhibitor SCH503034.
Vincent Madison, Andrew J Prongay, Zhuyan Guo, Nanhua Yao, John Pichardo, Edwin Jao

J Synchrotron Radiat· May 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of the HCV NS3/4A protease inhibitor (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3- [2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (Sch 503034) II. Key steps in structure-based optimization.
Andrew J Prongay, Zhuyan Guo, Nanhua Yao, John Pichardo, Thierry Fischmann, Edwin Jao

J Med Chem· May 2007

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (SCH 503034), a selective, potent, orally bioavailable hepatitis C virus NS3 protease inhibitor: a potential therapeutic agent for the treatment of hepatitis C infection.
Srikanth Venkatraman, Stéphane L Bogen, Ashok Arasappan, Frank Bennett, Kevin Chen, Edwin Jao

J Med Chem· October 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of SCH446211 (SCH6): a new ketoamide inhibitor of the HCV NS3 serine protease and HCV subgenomic RNA replication.
Stéphane L Bogen, Ashok Arasappan, Frank Bennett, Kevin Chen, Edwin Jao

J Med Chem· May 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Hydroxylated analogues of the orally active broad spectrum antifungal, Sch 51048 (1), and the discovery of posaconazole [Sch 56592; 2 or (S,S)-5].
Frank Bennett, Anil K Saksena, Raymond G Lovey, Yi-Tsung Liu, Naginbhai M Patel, Edwin Jao

Bioorg Med Chem Lett· January 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Addition-Rearrangement of Aryl- and Alkoxysulfonyl Isocyanates with 5-Methyl-Substituted 3,4-Dihydro-2-methoxy-2H-pyrans. Selective Synthesis of Functionalized 2-Piperidones(1).
Edwin Jao, Paul B. Slifer, Roger Lalancette, Stan S. Hall

J Org Chem· April 1996

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis