Publications by authors named "Edwin Tse"

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-Alkyl Sulfamates as a New Class of nsP2 Cysteine Protease Inhibitors with Broad-Spectrum Antialphaviral Activity.
Anirban Ghoshal, John D Sears, Mohammad Anwar Hossain, Edwin G Tse, Stefanie Howell

J Med Chem· November 2025

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-Alkyl Sulfamates as a New Class of nsP2 Cysteine Protease Inhibitors with Broad Spectrum Antialphaviral Activity.
Anirban Ghoshal, John D Sears, Mohammad Anwar Hossain, Edwin G Tse, Stefanie Howell

bioRxiv· July 2025

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A covalent chemical probe for Chikungunya nsP2 cysteine protease with antialphaviral activity and proteome-wide selectivity.
Anirban Ghoshal, Edwin G Tse, Mohammad Anwar Hossain, Kesatebrhan Haile Asressu, Eric M Merten

Sci Rep· March 2025

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A Covalent Chemical Probe for nsP2 Cysteine Protease with Antialphaviral Activity and Proteome-wide Selectivity.
Anirban Ghoshal, Edwin G Tse, Mohammad Anwar Hossain, Kesatebrhan Haile Asressu, Eric M Merten

Res Sq· November 2024

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Identification of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach.
Eric M Merten, John D Sears, Tina M Leisner, P Brian Hardy, Anirban Ghoshal, Edwin G Tse

Proc Natl Acad Sci U S A· October 2024

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Open Source Code Contributions to Global Health: The Case of Antimalarial Drug Discovery.
Gemma Turon, Edwin Tse, Xin Qiu, Matthew Todd, Miquel Duran-Frigola

ACS Med Chem Lett· September 2024

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Open Source Antibiotics: Simple Diarylimidazoles Are Potent against Methicillin-Resistant .
Dana M Klug, Edwin G Tse, Daniel G Silva, Yafeng Cao, Susan A Charman

ACS Infect Dis· December 2023

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Structure-Property Optimization of a Series of Imidazopyridines for Visceral Leishmaniasis.
Maria Dichiara, Quillon J Simpson, Antonio Quotadamo, Hitesh B Jalani, Anson X Huang, Edwin G Tse

ACS Infect Dis· August 2023

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The Metallodrug BOLD-100 Is a Potent Inhibitor of SARS-CoV-2 Replication and Has Broad-Acting Antiviral Activity.
Daniel S Labach, Hinissan P Kohio, Edwin A Tse, Ermela Paparisto, Nicole J Friesen

Biomolecules· July 2023

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An Open Drug Discovery Competition: Experimental Validation of Predictive Models in a Series of Novel Antimalarials.
Edwin G Tse, Laksh Aithani, Mark Anderson, Jonathan Cardoso-Silva, Giovanni Cincilla

J Med Chem· November 2021

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-Substitution Reactions in the Synthesis of a Promising Class of 1,2,4-Triazolo[4,3-]pyrazine-Based Antimalarials.
Marat Korsik, Edwin G Tse, David G Smith, William Lewis, Peter J Rutledge

J Org Chem· November 2020

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Open science approaches to COVID-19.
Edwin G Tse, Dana M Klug, Matthew H Todd

F1000Res· November 2020

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Nonclassical Phenyl Bioisosteres as Effective Replacements in a Series of Novel Open-Source Antimalarials.
Edwin G Tse, Sevan D Houston, Craig M Williams, G Paul Savage, Louis M Rendina

J Med Chem· October 2020

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The past, present and future of anti-malarial medicines.
Edwin G Tse, Marat Korsik, Matthew H Todd

Malar J· March 2019

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Experimentally Validated Pharmacoinformatics Approach to Predict hERG Inhibition Potential of New Chemical Entities.
Saba Munawar, Monique J Windley, Edwin G Tse, Matthew H Todd, Adam P Hill

Front Pharmacol· September 2018

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Comparison of knowledge, attitudes and practice of dental safety from eight countries at the turn of the century.
Raghunath Puttaiah, Kierste Miller, Daniela Raman Bedi, Sadashiva Shetty, Khalid Almas, Edwin Tse

J Contemp Dent Pract· January 2011

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Sample infection control needs assessment survey data from eight countries.
Raghunath Puttaiah, Jay D Shulman, Dennis Youngblood, Raman Bedi, Edwin Tse

Int Dent J· October 2009

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