Publications by authors named "Matthew Todd"

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Structure-activity relationships of fenarimol analogues with potent and activity against , the main causative agent of mycetoma.
Hung Phat Duong, Dmitrij Melechov, Wilson Lim, Jingyi Ma, Kymberley R Scroggie, Matthew H Todd

RSC Med Chem· December 2025

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Identification of spirodioxolane nsP2 helicase inhibitors with antialphaviral activity.
Hans J Oh, John D Sears, Bose Muthu Ramalingam, Rahman Shah Zaib Saleem, Zachary W Davis-Gilbert, Matthew H Todd

RSC Med Chem· October 2025

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Kinome analysis of Madurella mycetomatis identified kinases in the cell wall integrity pathway as novel potential therapeutic drug targets in eumycetoma caused by Madurella mycetomatis.
Mickey Konings, Nikolaos Strepis, Ri-Ichiroh Manabe, Akira Hasegawa, Somdatta Chaudhari, Matthew Todd

PLoS Negl Trop Dis· September 2025

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Tartrolon E rapidly blocks Toxoplasma gondii capacity to invade host cells.
Fernanda G Fumuso, Jason A Clement, Matthew J Todd, Roberta M O'Connor

Int J Parasitol Drugs Drug Resist· August 2025

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Structural basis for sirtuin 2 activity and modulation: Current state and opportunities.
Samuel P Bernhard, Francesc X Ruiz, Stacy Remiszewski, Matthew J Todd, Thomas Shenk

J Biol Chem· July 2025

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Use of imaging biomarkers and ambulatory functional endpoints in Duchenne muscular dystrophy clinical trials: Systematic review and machine learning-driven trend analysis.
Matthew Todd, Sanghoon Kang, Shunwen Wu, Devanand Adhin, Deok Yong Yoon

J Neuromuscul Dis· July 2025

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Open Source Code Contributions to Global Health: The Case of Antimalarial Drug Discovery.
Gemma Turon, Edwin Tse, Xin Qiu, Matthew Todd, Miquel Duran-Frigola

ACS Med Chem Lett· September 2024

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DNAJC9 prevents CENP-A mislocalization and chromosomal instability by maintaining the fidelity of histone supply chains.
Vinutha Balachandra, Roshan L Shrestha, Colin M Hammond, Shinjen Lin, Ivo A Hendriks, Matthew Am Todd

EMBO J· June 2024

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Identification of Dihydropyrazolo[1,5-]pyrazin-4(5)-ones as Cyclic Products of β-Amidomethyl Vinyl Sulfone Alphavirus Cysteine Protease Inhibitors.
Anirban Ghoshal, Álvaro F Magalhães, Kesatebrhan Haile Asressu, Mohammad Anwar Hossain, Matthew H Todd

Pharmaceuticals (Basel)· June 2024

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Implementing sustainable science in the lab.
Kathryn J Wattam, Matthew A M Todd, Anja Groth

Nat Cell Biol· January 2024

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Reaction hijacking inhibition of Plasmodium falciparum asparagine tRNA synthetase.
Stanley C Xie, Yinuo Wang, Craig J Morton, Riley D Metcalfe, Con Dogovski, Matthew H Todd

Nat Commun· January 2024

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Open Source Antibiotics: Simple Diarylimidazoles Are Potent against Methicillin-Resistant .
Dana M Klug, Edwin G Tse, Daniel G Silva, Yafeng Cao, Susan A Charman, Matthew H Todd

ACS Infect Dis· December 2023

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Synthesis of 1,2-Disubstituted Adamantane Derivatives by Construction of the Adamantane Framework.
Matthew Todd, Radim Hrdina

Molecules· November 2023

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Structure-Property Optimization of a Series of Imidazopyridines for Visceral Leishmaniasis.
Maria Dichiara, Quillon J Simpson, Antonio Quotadamo, Hitesh B Jalani, Anson X Huang, Matthew H Todd

ACS Infect Dis· August 2023

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Reaction hijacking inhibition of asparagine tRNA synthetase.
Stanley C Xie, Yinuo Wang, Craig J Morton, Riley D Metcalfe, Con Dogovski, Matthew H Todd

Res Sq· July 2023

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An allosteric inhibitor of sirtuin 2 deacetylase activity exhibits broad-spectrum antiviral activity.
Kathryn L Roche, Stacy Remiszewski, Matthew J Todd, John L Kulp, Liudi Tang

J Clin Invest· June 2023

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Target 2035 - an update on private sector contributions.
Suzanne Ackloo, Albert A Antolin, Jose Manuel Bartolome, Hartmut Beck, Alex Bullock, Matthew H Todd

RSC Med Chem· June 2023

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Antifungal Activity of Natural Naphthoquinones and Anthraquinones against Madurella mycetomatis.
Jingyi Ma, Matthew Todd, Wendy W J van de Sande, Bernhard Biersack

Chem Biodivers· May 2023

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VGF is required for recovery after focal stroke.
Hannah L Gillis, Alena Kalinina, Yingben Xue, Keqin Yan, Valérie Turcotte-Cardin, Matthew A M Todd

Exp Neurol· April 2023

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Perphenazine-Macrocycle Conjugates Rapidly Sequester the Aβ42 Monomer and Prevent Formation of Toxic Oligomers and Amyloid.
Sarah R Ball, Julius S P Adamson, Michael A Sullivan, Manuela R Zimmermann, Victor Lo, Matthew H Todd

ACS Chem Neurosci· January 2023

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The Marine Compound Tartrolon E Targets the Asexual and Early Sexual Stages of .
Alexis Cotto-Rosario, Emma Y D Miller, Fernanda G Fumuso, Jason A Clement, Matthew J Todd

Microorganisms· November 2022

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Pharmacologic Enhancement of Rotator Cuff Repair: A Narrative Review.
Maksim Vaysman, Matthew Alben, Matthew Todd, Charles Ruotolo

Orthop Rev (Pavia)· September 2022

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CACHE (Critical Assessment of Computational Hit-finding Experiments): A public-private partnership benchmarking initiative to enable the development of computational methods for hit-finding.
Suzanne Ackloo, Rima Al-Awar, Rommie E Amaro, Cheryl H Arrowsmith, Hatylas Azevedo, Matthew H Todd

Nat Rev Chem· April 2022

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Screening the pandemic response box identified benzimidazole carbamates, Olorofim and ravuconazole as promising drug candidates for the treatment of eumycetoma.
Wilson Lim, Bertrand Nyuykonge, Kimberly Eadie, Mickey Konings, Juli Smeets, Matthew Todd

PLoS Negl Trop Dis· February 2022

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Target 2035 - update on the quest for a probe for every protein.
Susanne Müller, Suzanne Ackloo, Arij Al Chawaf, Bissan Al-Lazikani, Albert Antolin, Matthew H Todd

RSC Med Chem· January 2022

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