Publications by authors named "Stacy Remiszewski"

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Structural basis for sirtuin 2 activity and modulation: Current state and opportunities.
Samuel P Bernhard, Francesc X Ruiz, Stacy Remiszewski, Matthew J Todd, Thomas Shenk

J Biol Chem· July 2025

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An allosteric inhibitor of sirtuin 2 blocks hepatitis B virus covalently closed circular DNA establishment and its transcriptional activity.
Liudi Tang, Stacy Remiszewski, Andrew Snedeker, Lillian W Chiang, Thomas Shenk

Antiviral Res· June 2024

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Inhibition of SIRT2 promotes death of human cytomegalovirus-infected peripheral blood monocytes via apoptosis and necroptosis.
Jennifer Cheung, Stacy Remiszewski, Lillian W Chiang, Ejaz Ahmad, Mohan Pal

Antiviral Res· September 2023

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An allosteric inhibitor of sirtuin 2 deacetylase activity exhibits broad-spectrum antiviral activity.
Kathryn L Roche, Stacy Remiszewski, Matthew J Todd, John L Kulp, Liudi Tang

J Clin Invest· June 2023

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Small-molecule inhibitors that disrupt the MTDH-SND1 complex suppress breast cancer progression and metastasis.
Minhong Shen, Yong Wei, Hahn Kim, Liling Wan, Yi-Zhou Jiang, Stacy Remiszewski

Nat Cancer· January 2022

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Benzazepinones and benzoxazepinones as antagonists of inhibitor of apoptosis proteins (IAPs) selective for the second baculovirus IAP repeat (BIR2) domain.
Andrew F Donnell, Christophe Michoud, Kenneth C Rupert, Xiaochun Han, Douglas Aguilar, Stacy W Remiszewski

J Med Chem· October 2013

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Optimization of benzodiazepinones as selective inhibitors of the X-linked inhibitor of apoptosis protein (XIAP) second baculovirus IAP repeat (BIR2) domain.
Robert F Kester, Andrew F Donnell, Yan Lou, Stacy W Remiszewski, Louis J Lombardo

J Med Chem· October 2013

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The structure of XIAP BIR2: understanding the selectivity of the BIR domains.
Christine Lukacs, Charles Belunis, Robert Crowther, Waleed Danho, Lin Gao, Stacy Remiszewski

Acta Crystallogr D Biol Crystallogr· September 2013

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Optimization of the in vitro cardiac safety of hydroxamate-based histone deacetylase inhibitors.
Michael D Shultz, Xueying Cao, Christine H Chen, Young Shin Cho, Nicole R Davis, Stacy Remiszewski

J Med Chem· July 2011

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Molecular and cellular basis for the anti-proliferative effects of the HDAC inhibitor LAQ824.
Peter Atadja, Meier Hsu, Paul Kwon, Nancy Trogani, Kapil Bhalla, Stacy Remiszewski

Novartis Found Symp· June 2004

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Use of a novel histone deacetylase inhibitor to induce apoptosis in cell lines of acute lymphoblastic leukemia.
Annette Romanski, Biserka Bacic, Gesine Bug, Heike Pfeifer, Hilal Gul, Stacy Remiszewski

Haematologica· April 2004

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Selective growth inhibition of tumor cells by a novel histone deacetylase inhibitor, NVP-LAQ824.
Peter Atadja, Lin Gao, Paul Kwon, Nancy Trogani, Heather Walker, Stacy Remiszewski

Cancer Res· January 2004

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The discovery of NVP-LAQ824: from concept to clinic.
Stacy W Remiszewski

Curr Med Chem· November 2003

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NVP-LAQ824 is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma.
Laurence Catley, Ellen Weisberg, Yu-Tzu Tai, Peter Atadja, Stacy Remiszewski

Blood· October 2003

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N-hydroxy-3-phenyl-2-propenamides as novel inhibitors of human histone deacetylase with in vivo antitumor activity: discovery of (2E)-N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide (NVP-LAQ824).
Stacy W Remiszewski, Lidia C Sambucetti, Kenneth W Bair, John Bontempo, David Cesarz

J Med Chem· October 2003

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Psammaplins from the sponge Pseudoceratina purpurea: inhibition of both histone deacetylase and DNA methyltransferase.
Ivette C Piña, Jeffrey T Gautschi, Gui-Yang-Sheng Wang, Miranda L Sanders, Francis J Schmitz, Stacy W Remiszewski

J Org Chem· May 2003

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Recent advances in the discovery of small molecule histone deacetylase inhibitors.
Stacy W Remiszewski

Curr Opin Drug Discov Devel· July 2002

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Inhibitors of human histone deacetylase: synthesis and enzyme and cellular activity of straight chain hydroxamates.
Stacy W Remiszewski, Lidia C Sambucetti, Peter Atadja, Kenneth W Bair, Wendy D Cornell

J Med Chem· February 2002

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Highly Regioselective Nitration Reactions Provide a Versatile Method of Functionalizing Benzocycloheptapyridine Tricyclic Ring Systems: Application toward Preparation of Nanomolar Inhibitors of Farnesyl Protein Transferase.
F. George Njoroge, Bancha Vibulbhan, Patrick Pinto, Tze-Ming Chan, Rebecca Osterman, Stacy Remiszewski

J Org Chem· February 1998

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