Publications by authors named "Elaine D MacKenzie"

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Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis.
Simone Cardaci, Liang Zheng, Gillian MacKay, Niels J F van den Broek, Elaine D MacKenzie

Nat Cell Biol· October 2015

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Fumarate induces redox-dependent senescence by modifying glutathione metabolism.
Liang Zheng, Simone Cardaci, Livnat Jerby, Elaine D MacKenzie, Marco Sciacovelli

Nat Commun· January 2015

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Reversed argininosuccinate lyase activity in fumarate hydratase-deficient cancer cells.
Liang Zheng, Elaine D MacKenzie, Saadia A Karim, Ann Hedley, Karen Blyth

Cancer Metab· March 2013

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Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase.
Christian Frezza, Liang Zheng, Ori Folger, Kartik N Rajagopalan, Elaine D MacKenzie

Nature· August 2011

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Cardiolipin provides an essential activating platform for caspase-8 on mitochondria.
Francois Gonzalvez, Zachary T Schug, Riekelt H Houtkooper, Elaine D MacKenzie, David G Brooks

J Cell Biol· November 2008

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Cell-permeating alpha-ketoglutarate derivatives alleviate pseudohypoxia in succinate dehydrogenase-deficient cells.
Elaine D MacKenzie, Mary A Selak, Daniel A Tennant, Lloyd J Payne, Stuart Crosby

Mol Cell Biol· May 2007

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Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase.
Mary A Selak, Sean M Armour, Elaine D MacKenzie, Houda Boulahbel, David G Watson

Cancer Cell· January 2005

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