Publications by authors named "Elizabeth Creasey"

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Bidirectional CRISPR screens decode a GLIS3-dependent fibrotic cell circuit.
Vladislav Pokatayev, Alok Jaiswal, Angela R Shih, Åsa Segerstolpe, Bihua Li, Elizabeth A Creasey

Nature· January 2026

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Autoimmune disease risk gene ANKRD55 promotes TH17 effector function through metabolic modulation.
Jinjin Xu, Lingjia Kong, Elizabeth A Creasey, Sneha Rath, Lei Deng

J Exp Med· November 2025

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Nuclear receptor coregulator NRIP1 R448G modulates T cell gut homing to control intestinal inflammation.
Xiangjun Chen, Hee Seung Hwang, Bihua Li, Yanhua Zhao, Koushik Ghosh, Elizabeth A Creasey

Proc Natl Acad Sci U S A· September 2025

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The Ulcerative Colitis-Associated Gene NXPE1 Catalyzes Glycan Modifications on Colonic Mucin.
Ranad Humeidi, Noriko Oshiro-Rapley, Xiebin Gu, Joon Soo An, Ashwin N Ananthakrishnan, Elizabeth A Creasey

J Am Chem Soc· March 2025

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Translational genetics identifies a phosphorylation switch in CARD9 required for innate inflammatory responses.
Marta Brandt, Zhifang Cao, Chirag Krishna, Jennifer L Reedy, Xiebin Gu, Elizabeth A Creasey

Cell Rep· March 2024

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The landscape of immune dysregulation in Crohn's disease revealed through single-cell transcriptomic profiling in the ileum and colon.
Lingjia Kong, Vladislav Pokatayev, Ariel Lefkovith, Grace T Carter, Elizabeth A Creasey

Immunity· December 2023

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Genetic vulnerability to Crohn's disease reveals a spatially resolved epithelial restitution program.
Toru Nakata, Chenhao Li, Toufic Mayassi, Helen Lin, Koushik Ghosh, Elizabeth A Creasey

Sci Transl Med· October 2023

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Constitutively active autophagy in macrophages dampens inflammation through metabolic and post-transcriptional regulation of cytokine production.
Jinjin Xu, Lingjia Kong, Blayne A Oliver, Bihua Li, Elizabeth A Creasey

Cell Rep· July 2023

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The landscape of immune dysregulation in Crohn's disease revealed through single-cell transcriptomic profiling in the ileum and colon.
Lingjia Kong, Vladislav Pokatayev, Ariel Lefkovith, Grace T Carter, Elizabeth A Creasey

Immunity· February 2023

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pH sensing controls tissue inflammation by modulating cellular metabolism and endo-lysosomal function of immune cells.
Xiangjun Chen, Alok Jaiswal, Zachary Costliow, Paula Herbst, Elizabeth A Creasey

Nat Immunol· July 2022

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The schizophrenia-associated variant in SLC39A8 alters protein glycosylation in the mouse brain.
Robert G Mealer, Sarah E Williams, Maxence Noel, Bo Yang, Alexandria K D'Souza, Elizabeth A Creasey

Mol Psychiatry· March 2022

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SdhA blocks disruption of the Legionella-containing vacuole by hijacking the OCRL phosphatase.
Won Young Choi, Seongok Kim, Philipp Aurass, Wenwen Huo, Elizabeth A Creasey

Cell Rep· November 2021

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A missense variant in confers risk for Crohn's disease by disrupting manganese homeostasis and intestinal barrier integrity.
Toru Nakata, Elizabeth A Creasey, Motohiko Kadoki, Helen Lin, Martin K Selig

Proc Natl Acad Sci U S A· November 2020

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Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis.
Christopher S Smillie, Moshe Biton, Jose Ordovas-Montanes, Keri M Sullivan, Grace Burgin, Elizabeth A Creasey

Cell· July 2019

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is a colitis risk gene that regulates stability of epithelial adherens junctions.
Vishnu Mohanan, Toru Nakata, A Nicole Desch, Chloé Lévesque, Angela Boroughs, Elizabeth Creasey

Science· March 2018

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Indoleacrylic Acid Produced by Commensal Peptostreptococcus Species Suppresses Inflammation.
Marta Wlodarska, Chengwei Luo, Raivo Kolde, Eva d'Hennezel, John W Annand, Elizabeth A Creasey

Cell Host Microbe· July 2017

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Maintenance of vacuole integrity by bacterial pathogens.
Elizabeth A Creasey, Ralph R Isberg

Curr Opin Microbiol· February 2014

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The protein SdhA maintains the integrity of the Legionella-containing vacuole.
Elizabeth A Creasey, Ralph R Isberg

Proc Natl Acad Sci U S A· February 2012

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A Legionella pneumophila-translocated substrate that is required for growth within macrophages and protection from host cell death.
Rita K Laguna, Elizabeth A Creasey, Zhiru Li, Nicole Valtz, Ralph R Isberg

Proc Natl Acad Sci U S A· December 2006

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Structural and functional studies of the enteropathogenic Escherichia coli type III needle complex protein EscJ.
Valérie F Crepin, Sunil Prasannan, Rob K Shaw, Rebecca K Wilson, Elizabeth Creasey

Mol Microbiol· March 2005

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SepL, a protein required for enteropathogenic Escherichia coli type III translocation, interacts with secretion component SepD.
Colin B O'Connell, Elizabeth A Creasey, Stuart Knutton, Simon Elliott, Lynette J Crowther

Mol Microbiol· June 2004

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CesAB is an enteropathogenic Escherichia coli chaperone for the type-III translocator proteins EspA and EspB.
Elizabeth A Creasey, Devorah Friedberg, Robert K Shaw, Tatiana Umanski, Stuart Knutton

Microbiology (Reading)· December 2003

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Yeast two-hybrid system survey of interactions between LEE-encoded proteins of enteropathogenic Escherichia coli.
Elizabeth A Creasey, Robin M Delahay, Sarah J Daniell, Gad Frankel

Microbiology (Reading)· August 2003

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CesT is a bivalent enteropathogenic Escherichia coli chaperone required for translocation of both Tir and Map.
Elizabeth A Creasey, Robin M Delahay, Alexandra A Bishop, Robert K Shaw, Brendan Kenny

Mol Microbiol· January 2003

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